procarbazine has been researched along with Complications, Neoplastic Pregnancy in 12 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The association between Hodgkin's disease and pregnancy is rare." | 2.38 | [Hodgkin's disease and pregnancy. 3 case reports and a review of the literature]. ( Abboud, J; Chahine, G; Nasnas, R; Nasrallah, T, 1993) |
| "Twelve women (12%) experienced 13 miscarriages after a median of 50 months (range, 13-120) from the end of therapy." | 1.38 | Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma. ( Alfò, M; Annechini, G; Cavalieri, E; De Sanctis, V; Enrici, RM; Filippone, FR; Minniti, G; Muni, R; Osti, MF; Pulsoni, A; Valeriani, M, 2012) |
| "The peak incidence of Hodgkin's disease occurs during the reproductive age, and its association with pregnancy is at a rate of between 1:1,000-1:6,000." | 1.28 | Maternal and foetal outcome following Hodgkin's disease in pregnancy. ( Degendorfer, P; Koren, G; Lishner, M; Panzarella, T; Sutcliffe, SB; Zemlickis, D, 1992) |
| "Procarbazine and BCNU were given for 5 months before conception and throughout the first and second trimesters, and streptozotocin was given throughout the third trimester." | 1.27 | Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy. ( Chudley, AE; Schapira, DV, 1984) |
| "Br." | 1.27 | [Pregnancy and fetal development after therapy of Hodgkin's disease]. ( Slanina, J; Spratler, J; Wannenmacher, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Russell, J | 1 |
| Collins, A | 1 |
| Fowler, A | 1 |
| Karanth, M | 1 |
| Saha, C | 1 |
| Docherty, S | 1 |
| Padayatty, J | 1 |
| Maw, K | 1 |
| Lentell, I | 1 |
| Cooke, L | 1 |
| Hodson, A | 1 |
| Shah, N | 1 |
| Sadullah, S | 1 |
| Grigoropoulos, N | 1 |
| Qian, W | 1 |
| Kirkwood, AA | 1 |
| Uttenthal, BJ | 1 |
| Johnson, P | 1 |
| Follows, GA | 1 |
| De Sanctis, V | 1 |
| Filippone, FR | 1 |
| Alfò, M | 1 |
| Muni, R | 1 |
| Cavalieri, E | 1 |
| Pulsoni, A | 1 |
| Annechini, G | 1 |
| Valeriani, M | 1 |
| Osti, MF | 1 |
| Minniti, G | 1 |
| Enrici, RM | 1 |
| Schapira, DV | 1 |
| Chudley, AE | 1 |
| Dein, RA | 1 |
| Mennuti, MT | 1 |
| Kovach, P | 1 |
| Gabbe, SG | 1 |
| Abboud, J | 1 |
| Nasrallah, T | 1 |
| Chahine, G | 1 |
| Nasnas, R | 1 |
| Avilés, A | 3 |
| Neri, N | 1 |
| Díaz-Maqueo, JC | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| García, EL | 1 |
| Zepeda, G | 1 |
| Cruz, J | 1 |
| Lishner, M | 1 |
| Zemlickis, D | 1 |
| Degendorfer, P | 1 |
| Panzarella, T | 1 |
| Sutcliffe, SB | 1 |
| Koren, G | 1 |
| Lacher, MJ | 1 |
| Toner, K | 1 |
| Baĭsogolov, GD | 1 |
| Slanina, J | 1 |
| Wannenmacher, M | 1 |
| Spratler, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for procarbazine and Complications, Neoplastic Pregnancy
| Article | Year |
|---|---|
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
[Hodgkin's disease and pregnancy. 3 case reports and a review of the literature].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Bone Marrow Examination; C | 1993 |
10 other studies available for procarbazine and Complications, Neoplastic Pregnancy
| Article | Year |
|---|---|
Advanced Hodgkin lymphoma in the East of England: a 10-year comparative analysis of outcomes for real-world patients treated with ABVD or escalated-BEACOPP, aged less than 60 years, compared with 5-year extended follow-up from the RATHL trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Top | 2021 |
Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma.
Topics: Abortion, Spontaneous; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Congenital | 2012 |
Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Fema | 1984 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
[Hodgkin's disease during pregnancy. Study of late effects in the newborn infants].
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chrom | 1991 |
Maternal and foetal outcome following Hodgkin's disease in pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Birth Weight; Case-Control Studies; Cesarean | 1992 |
Pregnancies and menstrual function before and after combined radiation (RT) and chemotherapy (TVPP) for Hodgkin's disease.
Topics: Adolescent; Adult; Age Factors; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Combined | 1986 |
[Clinical studies of the diagnosis and treatment of Hodgkin's disease (1967-1986)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Female; | 1987 |
[Pregnancy and fetal development after therapy of Hodgkin's disease].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Embryonic and Fetal Develop | 1985 |