procarbazine has been researched along with Colorectal Neoplasms in 7 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To quantify the rate of colorectal cancer according to radiation dose to the large bowel and procarbazine dose among HL survivors." | 8.31 | Association of Radiation and Procarbazine Dose With Risk of Colorectal Cancer Among Survivors of Hodgkin Lymphoma. ( Aleman, BMP; Aznar, MC; Cutter, DJ; Darby, SC; Geurts, YM; Janus, CPM; John, KM; Krol, ADG; Ntentas, G; Ramroth, J; Roberti, S; Roesink, JM; Schaapveld, M; Shakir, R; van der Maazen, RWM; van Leeuwen, FE; Zijlstra, JM, 2023) |
| "Hodgkin lymphoma survivors treated with infradiaphragmatic radiotherapy (IRT) and/or procarbazine have an increased risk of developing colorectal cancer." | 8.12 | Cost-Effectiveness of Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors Treated with Procarbazine and/or Infradiaphragmatic Radiotherapy. ( Aleman, BMP; Bisseling, TM; Carvalho, B; de Boer, JP; Gini, A; Janus, CPM; Lansdorp-Vogelaar, I; Lugtenburg, PJ; Meijer, GA; Moons, LMG; Petersen, EJ; Rigter, LS; Roesink, JM; Snaebjornsson, P; Spaander, MCW; van der Maazen, RWM; van Leerdam, ME; van Leeuwen, FE; Verbeek, WHM; Ykema, BLM, 2022) |
| "Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose." | 7.85 | Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017) |
| " Hodgkin lymphoma survivors who were treated with infradiaphragmatic radiotherapy and/or high-dose procarbazine have an increased risk to develop colorectal cancer." | 5.24 | Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design. ( Aleman, BM; Bisseling, TM; Bleiker, EM; Carvalho, B; Cats, A; de Boer, JP; Janus, CP; Jóźwiak, K; Lansdorp-Vogelaar, I; Lugtenburg, PJ; Meijer, GA; Moons, LM; Petersen, EJ; Raemaekers, JM; Rigter, LS; Roesink, JM; Snaebjornsson, P; Spaander, MC; Te Riele, H; van der Maazen, RW; van Leerdam, ME; van Leeuwen, FE, 2017) |
| "To quantify the rate of colorectal cancer according to radiation dose to the large bowel and procarbazine dose among HL survivors." | 4.31 | Association of Radiation and Procarbazine Dose With Risk of Colorectal Cancer Among Survivors of Hodgkin Lymphoma. ( Aleman, BMP; Aznar, MC; Cutter, DJ; Darby, SC; Geurts, YM; Janus, CPM; John, KM; Krol, ADG; Ntentas, G; Ramroth, J; Roberti, S; Roesink, JM; Schaapveld, M; Shakir, R; van der Maazen, RWM; van Leeuwen, FE; Zijlstra, JM, 2023) |
| "Hodgkin lymphoma survivors treated with infradiaphragmatic radiotherapy (IRT) and/or procarbazine have an increased risk of developing colorectal cancer." | 4.12 | Cost-Effectiveness of Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors Treated with Procarbazine and/or Infradiaphragmatic Radiotherapy. ( Aleman, BMP; Bisseling, TM; Carvalho, B; de Boer, JP; Gini, A; Janus, CPM; Lansdorp-Vogelaar, I; Lugtenburg, PJ; Meijer, GA; Moons, LMG; Petersen, EJ; Rigter, LS; Roesink, JM; Snaebjornsson, P; Spaander, MCW; van der Maazen, RWM; van Leerdam, ME; van Leeuwen, FE; Verbeek, WHM; Ykema, BLM, 2022) |
| "Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose." | 3.85 | Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017) |
| "The SIR for colorectal cancer was 4." | 1.38 | Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study. ( Armstrong, GT; Constine, LS; Crotty, C; Diller, L; Hammond, S; Henderson, TO; Inskip, P; Leisenring, W; Meadows, A; Nathan, PC; Neglia, J; Oeffinger, KC; Robison, LL; Rubin, DT; Smith, SA; Stovall, M; Whitton, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Ykema, BLM | 1 |
| Gini, A | 1 |
| Rigter, LS | 3 |
| Spaander, MCW | 2 |
| Moons, LMG | 1 |
| Bisseling, TM | 3 |
| de Boer, JP | 4 |
| Verbeek, WHM | 1 |
| Lugtenburg, PJ | 3 |
| Janus, CPM | 3 |
| Petersen, EJ | 3 |
| Roesink, JM | 4 |
| van der Maazen, RWM | 3 |
| Aleman, BMP | 3 |
| Meijer, GA | 3 |
| van Leeuwen, FE | 5 |
| Snaebjornsson, P | 3 |
| Carvalho, B | 2 |
| van Leerdam, ME | 4 |
| Lansdorp-Vogelaar, I | 2 |
| Geurts, YM | 1 |
| Shakir, R | 1 |
| Ntentas, G | 1 |
| Roberti, S | 1 |
| Aznar, MC | 1 |
| John, KM | 1 |
| Ramroth, J | 1 |
| Krol, ADG | 1 |
| Zijlstra, JM | 2 |
| Darby, SC | 1 |
| Cutter, DJ | 1 |
| Schaapveld, M | 2 |
| van Eggermond, AM | 1 |
| Janus, CP | 2 |
| Krol, AD | 1 |
| van der Maazen, RW | 2 |
| Kremer, LC | 1 |
| Louwman, MW | 1 |
| Visser, O | 1 |
| De Bruin, ML | 1 |
| Aleman, BM | 2 |
| Moons, LM | 2 |
| Cats, A | 2 |
| Kuipers, EJ | 1 |
| Bruno, MJ | 1 |
| Dekker, E | 1 |
| Spaander, MC | 1 |
| Raemaekers, JM | 1 |
| Bleiker, EM | 1 |
| Jóźwiak, K | 1 |
| Te Riele, H | 1 |
| Henderson, TO | 2 |
| Oeffinger, KC | 2 |
| Whitton, J | 2 |
| Leisenring, W | 2 |
| Neglia, J | 2 |
| Meadows, A | 2 |
| Crotty, C | 2 |
| Rubin, DT | 2 |
| Diller, L | 2 |
| Inskip, P | 2 |
| Smith, SA | 2 |
| Stovall, M | 2 |
| Constine, LS | 2 |
| Hammond, S | 2 |
| Armstrong, GT | 2 |
| Robison, LL | 2 |
| Nathan, PC | 2 |
1 trial available for procarbazine and Colorectal Neoplasms
| Article | Year |
|---|---|
Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design.
Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Protocols; Colonoscopy; Colo | 2017 |
6 other studies available for procarbazine and Colorectal Neoplasms
| Article | Year |
|---|---|
Cost-Effectiveness of Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors Treated with Procarbazine and/or Infradiaphragmatic Radiotherapy.
Topics: Adult; Aged; Colonoscopy; Colorectal Neoplasms; Cost-Benefit Analysis; Early Detection of Cancer; Ho | 2022 |
Association of Radiation and Procarbazine Dose With Risk of Colorectal Cancer Among Survivors of Hodgkin Lymphoma.
Topics: Case-Control Studies; Child; Colorectal Neoplasms; Female; Hodgkin Disease; Humans; Male; Procarbazi | 2023 |
Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colon; Colo | 2017 |
High prevalence of advanced colorectal neoplasia and serrated polyposis syndrome in Hodgkin lymphoma survivors.
Topics: Aged; Cancer Survivors; Cohort Studies; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Female; H | 2019 |
Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study.
Topics: Adolescent; Adult; Antineoplastic Agents; Canada; Child; Colorectal Neoplasms; Gastrointestinal Neop | 2012 |
Summaries for patients. Increased risk for gastrointestinal cancer in childhood cancer survivors.
Topics: Adolescent; Adult; Antineoplastic Agents; Canada; Child; Colorectal Neoplasms; Gastrointestinal Neop | 2012 |