procarbazine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of Hodgkin's disease resulted in complete remission and complete disappearance of the pontine abnormality." | 1.29 | Hodgkin's disease associated with central pontine myelinolysis. ( Carrol, CL; Chintagumpala, MM; Dreyer, ZE; Fishman, MA; Mahoney, DH; McClain, K; Steuber, CP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, R | 1 |
| Abrey, LE | 1 |
| Rosenblum, MK | 1 |
| DeAngelis, LM | 1 |
| Chintagumpala, MM | 1 |
| Mahoney, DH | 1 |
| McClain, K | 1 |
| Dreyer, ZE | 1 |
| Fishman, MA | 1 |
| Carrol, CL | 1 |
| Steuber, CP | 1 |
1 review available for procarbazine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cranial Irradia | 2004 |
1 other study available for procarbazine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Hodgkin's disease associated with central pontine myelinolysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Dacarbazine; Demyelinating Disease | 1993 |