procarbazine has been researched along with Chromosomal Translocation in 7 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This has changed with the long-term follow-up analysis of the EORTC and RTOG trials on procarbazine, lomustine, and vincristine (PCV) chemotherapy in anaplastic oligodendroglioma." | 3.79 | How to use molecular markers when caring for a patient with brain cancer: 1P/19Q as a predictive and prognostic marker in the neuro-oncology clinic. ( van den Bent, MJ, 2013) |
| "Sixty-five patients with Stage I to III follicular lymphoma were randomized." | 2.71 | A prospective randomized study to compare the molecular response rates between central lymphatic irradiation and intensive alternating triple chemotherapy in the treatment of stage I-III follicular lymphoma. ( Cabanillas, F; Cox, JD; Ha, CS; Lee, MS; McLaughlin, P; Mesina, OM; Rodriguez, MA; Romaguera, JE; Tucker, SL; Younes, A, 2005) |
| "Group two included Hodgkin's disease patients who were treated 12-24 years previously and have been continuously free of disease." | 1.28 | The frequency of translocations after treatment for Hodgkin's disease. ( Brown, JM; Evans, JW; Mori, M; Smith, LM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van den Bent, MJ | 1 |
| Ha, CS | 1 |
| Cabanillas, F | 2 |
| Lee, MS | 1 |
| Tucker, SL | 1 |
| McLaughlin, P | 1 |
| Rodriguez, MA | 1 |
| Younes, A | 1 |
| Romaguera, JE | 1 |
| Mesina, OM | 1 |
| Cox, JD | 1 |
| Freireich, EJ | 1 |
| Keating, M | 1 |
| Barlogie, B | 1 |
| Osaka, M | 1 |
| Rowley, JD | 1 |
| Zeleznik-Le, NJ | 1 |
| Blijleven, WG | 1 |
| Vogel, E | 1 |
| Smith, LM | 1 |
| Evans, JW | 1 |
| Mori, M | 1 |
| Brown, JM | 1 |
| Vormittag, W | 1 |
1 review available for procarbazine and Chromosomal Translocation
| Article | Year |
|---|---|
The hematologic malignancies. Leukemia, lymphoma, and myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Doxor | 1984 |
1 trial available for procarbazine and Chromosomal Translocation
| Article | Year |
|---|---|
A prospective randomized study to compare the molecular response rates between central lymphatic irradiation and intensive alternating triple chemotherapy in the treatment of stage I-III follicular lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cyclophosphamide; | 2005 |
5 other studies available for procarbazine and Chromosomal Translocation
| Article | Year |
|---|---|
How to use molecular markers when caring for a patient with brain cancer: 1P/19Q as a predictive and prognostic marker in the neuro-oncology clinic.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosome Deletion; Chromosomes, H | 2013 |
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).
Topics: Acute Disease; Amino Acid Sequence; Animals; Antineoplastic Combined Chemotherapy Protocols; Base Se | 1999 |
The mutational spectrum of procarbazine in Drosophila melanogaster.
Topics: Administration, Oral; Animals; Chromosome Deletion; Drosophila melanogaster; Female; Genes, Dominant | 1977 |
The frequency of translocations after treatment for Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 4; Combined Modality Therap | 1992 |
[Cytostatic immunosuppressive therapy, chromosomal aberrations and carcinogenic effect (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chromosome Aberrations; Chromosomes, Human, 1-3; C | 1974 |