procarbazine has been researched along with Chemical and Drug Induced Liver Injury in 7 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Procarbazine hydrochloride is an oral alkylating agent primarily used as a component of chemotherapy regimens for Hodgkin's lymphoma, as well as in regimens for primary central nervous system lymphoma and high-grade gliomas." | 2.46 | Procarbazine-induced hepatotoxicity: case report and review of the literature. ( Becker-Koepke, S; Di Bisceglie, AM; Fesler, MJ; Petruska, PJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Fesler, MJ | 1 |
| Becker-Koepke, S | 1 |
| Di Bisceglie, AM | 1 |
| Petruska, PJ | 1 |
| Mian, M | 1 |
| Farsad, M | 1 |
| Pescosta, N | 1 |
| Casini, M | 1 |
| Cavattoni, IM | 1 |
| Deola, S | 1 |
| Cortelazzo, S | 1 |
| Schein, PS | 1 |
| Winokur, SH | 1 |
| Konrad, H | 1 |
| Engelmann, C | 1 |
| Zubaidi, G | 1 |
3 reviews available for procarbazine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Procarbazine-induced hepatotoxicity: case report and review of the literature.
Topics: Aged; Alanine Transaminase; Antineoplastic Agents, Alkylating; Chemical and Drug Induced Liver Injur | 2010 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical a | 1975 |
4 other studies available for procarbazine and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Bendamustine salvage for the treatment of relapsed Hodgkin's lymphoma after allogeneic bone marrow transplantation.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Alkylating; Antineoplastic Combined C | 2013 |
[Cytostatic therapy of lymphogranulomatosis].
Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Cysti | 1972 |