procarbazine has been researched along with Central Nervous System Disease in 6 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaplan, RS | 1 |
| Wiernik, PH | 2 |
| Sullivan, KM | 1 |
| Storb, R | 1 |
| Shulman, HM | 1 |
| Shaw, CM | 1 |
| Spence, A | 1 |
| Beckham, C | 1 |
| Clift, RA | 1 |
| Buckner, CD | 1 |
| Stewart, P | 1 |
| Thomas, ED | 2 |
| Nomura, K | 1 |
| Ohno, R | 1 |
| Weiss, GB | 1 |
| Weiden, PL | 1 |
| Chamberlain, MC | 1 |
| Levin, VA | 1 |
| Weiss, HD | 1 |
| Walker, MD | 1 |
2 reviews available for procarbazine and Central Nervous System Disease
| Article | Year |
|---|---|
[Neurologic complications of chemotherapy (vincristine etc.)].
Topics: Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Cisplatin; Humans; Peripheral | 1999 |
Neurotoxicity of commonly used antineoplastic agents (second of two parts).
Topics: Achilles Tendon; Animals; Antineoplastic Agents; Autonomic Nervous System; Central Nervous System Di | 1974 |
4 other studies available for procarbazine and Central Nervous System Disease
| Article | Year |
|---|---|
Neurotoxicity of antineoplastic drugs.
Topics: Altretamine; Antineoplastic Agents; Asparaginase; Brain; Central Nervous System Diseases; Cisplatin; | 1982 |
Immediate and delayed neurotoxicity after mechlorethamine preparation for bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Central Nervous System; Central Ne | 1982 |
Central nervous system disturbances after combined administration of procarbazine and mechlorethamine.
Topics: Adult; Central Nervous System Diseases; Drug Therapy, Combination; Humans; Male; Mechlorethamine; Pr | 1977 |
Adjuvant chemotherapy for primary lymphoma of the central nervous system.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Dise | 1990 |