procarbazine has been researched along with Cataract in 1 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The induction of dominant cataract mutations by procarbazine was studied concomitantly with the induction of specific-locus mutations in treated male mice." | 7.67 | Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice. ( Favor, J; Kratochvilova, J; Neuhäuser-Klaus, A, 1988) |
| "The induction of dominant cataract mutations by procarbazine was studied concomitantly with the induction of specific-locus mutations in treated male mice." | 3.67 | Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice. ( Favor, J; Kratochvilova, J; Neuhäuser-Klaus, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kratochvilova, J | 1 |
| Favor, J | 1 |
| Neuhäuser-Klaus, A | 1 |
1 other study available for procarbazine and Cataract
| Article | Year |
|---|---|
Dominant cataract and recessive specific-locus mutations detected in offspring of procarbazine-treated male mice.
Topics: Abnormalities, Drug-Induced; Animals; Cataract; Epistasis, Genetic; Fertility; Genes, Dominant; Gene | 1988 |