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procarbazine and Carcinoma, Epidermoid

procarbazine has been researched along with Carcinoma, Epidermoid in 27 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
" In the absence of evidence of a dose-response curve for platinum, the lower dosage schedules that can be used with acceptable toxicity on an outpatient basis should be selected."3.75Chemotherapy for squamous cell carcinoma of the head and neck: a progress report. ( Glick, JH; Taylor, SG; Zehngebot, LM, 1980)
"2) Non-Hodgkin's lymphoma has not appeared in any of the patients in this series."1.28[Second neoplasms as a late complication of the treatment of Hodgkin's disease]. ( Alvarez, A; Colomé, JA; del Potro, E; Díaz Mediavilla, J; González, FA; Martínez, R; Morales, MD; Villegas, A, 1992)
"Three patients with Stage III or IVB Hodgkin's disease were cured with MOPP (regimen of nitrogen mustard, Oncovin, prednisone, and procarbazine) and/or B-DOPA (regimen of bleomycin, dacarbazine, Oncovin, prednisone, and Adriamycin)."1.28Secondary uncommon solid neoplasms in cured Hodgkin's disease and follow-up of the original B-DOPA chemotherapy patient group. ( Lokich, JJ, 1990)
"Despite the dramatic response of Hodgkin's disease to intensive chemotherapy, the skin lesion was rapidly transformed into squamous cell carcinoma in 10 weeks."1.26Rapid development of keratoacanthoma and accelerated transformation into squamous cell carcinoma of the skin: a mutagenic effect of polychemotherapy in a patient with Hodgkin's disease? ( Poleksic, S; Yeung, KY, 1978)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199024 (88.89)18.7374
1990's3 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glick, JH1
Zehngebot, LM1
Taylor, SG1
Veronesi, A3
Magri, MD1
Trovò, MG3
Tirelli, U3
Galligioni, E2
Tumolo, S2
Grigoletto, E3
Hoffman, PC2
Newman, SB2
Golomb, HM5
Demeester, TR4
Blough, RR1
Sovik, CA1
De Paoli, A2
Franchin, G2
Roncadin, M2
Magri, M1
Carbone, A2
Laing, AH1
Berry, RJ1
Newman, CR1
Peto, J1
Mintz, U1
Bitran, JD4
Cooksey, JA1
Desser, RK3
Palmer, RL1
Kroening, PM1
Hansen, HH1
Selawry, OS1
Simon, R1
Carr, DT1
van Wyk, CE1
Tucker, RD1
Sealy, R1
Alberto, P2
Brunner, KW1
Martz, G1
Obrecht, J1
Sonntag, RW1
Colman, M1
Evans, R1
Billings, A1
Griem, M1
Rubenstein, L1
Shapiro, C1
Weinstock, LT1
Cheng, CC1
Poleksic, S1
Yeung, KY1
DeMeester, T1
Morales, MD1
González, FA1
Villegas, A1
del Potro, E1
Díaz Mediavilla, J1
Martínez, R1
Alvarez, A1
Colomé, JA1
Lokich, JJ1
Minatel, E1
Magri, DM1
Wright, JC1
Wang, QL1
Finkelstein, DM1
Ettinger, DS1
Ruckdeschel, JC1
Shepard, KV1
Skosey, C1
Swierz, J1
Bonadonna, G1
Tancini, G1
Bajetta, E1
Hoerni, B1
Brunet, R1
Hoerni-Simon, G1
Deckers, C1
Deckers-Passau, L1
Maisin, J1
Gauthier, JM1
Mace, F1
Arseneau, JC1
Sponzo, RW1
Levin, DL1
Schnipper, LE1
Bonner, H1
Young, RC1
Canellos, GP1
Johnson, RE1
DeVita, VT1
Gottlieb, JA1
Serpick, AA1

Reviews

3 reviews available for procarbazine and Carcinoma, Epidermoid

ArticleYear
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
    American journal of otolaryngology, 1980, Volume: 1, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic;

1980
Update in cancer chemotherapy, Part III: Lung cancer, Part 1.
    Journal of the National Medical Association, 1985, Volume: 77, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin; Carcinoma; C

1985
[Current views of the treatment of non-microcellular carcinoma of the lungs].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Jun-01, Volume: 38, Issue:11

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cyc

1985

Trials

7 trials available for procarbazine and Carcinoma, Epidermoid

ArticleYear
Chemotherapy for squamous cell carcinoma of the head and neck: a progress report.
    American journal of otolaryngology, 1980, Volume: 1, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil; Clinical Trials as Topic;

1980
Metastatic non-small cell bronchogenic carcinoma: a randomized trial of sequential vs combination chemotherapy.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

1983
Treatment of inoperable carcinoma of bronchus.
    Lancet (London, England), 1975, Dec-13, Volume: 2, Issue:7946

    Topics: Adenocarcinoma; Administration, Oral; Aged; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell

1975
Hexamethylmelamine, bleomycin, and CCNU chemotherapy for patients with squamous cell carcinoma, large cell carcinoma, and adenocarcinoma of the lung unresponsive to cyclophosphamide, adriamycin, methotrexate, and procarbazine.
    Cancer treatment reports, 1978, Volume: 62, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Altretamine; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell

1978
Combination chemotherapy of advanced lung cancer: a randomized trial.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell;

1976
Treatment of bronchogenic carcinoma with simultaneous or sequential combination chemotherapy, including methotrexate, cyclophosphamide, procarbazine and vincristine.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cel

1976
Combined radiotherapy and chemotherapy versus radiotherapy alone in locally advanced epidermoid bronchogenic carcinoma. A randomized study.
    Cancer, 1990, Feb-01, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; C

1990

Other Studies

18 other studies available for procarbazine and Carcinoma, Epidermoid

ArticleYear
Combination chemotherapy with vincristine, carmustine, carmustine (BCNU), and bleomycin in patients with squamous cell bronchial carcinoma resistant to cyclophosphamide, doxorubicin, methotrexate, and procarbazine (CAMP).
    Cancer treatment reports, 1982, Volume: 66, Issue:10

    Topics: Adult; Aged; Bleomycin; Bronchial Neoplasms; Carcinoma, Squamous Cell; Carmustine; Cyclophosphamide;

1982
Combined radiotherapy and chemotherapy with cyclophosphamide, adriamycin, methotrexate, procarbazine (CAMP) in 64 consecutive patients with epidermoid bronchogenic carcinoma, limited disease: a prospective study.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:6

    Topics: Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophosphamide; Doxorubicin; Drug

1982
Comparison of low dose radiation therapy alone or combined with procarbazine (NSC-77213) for unresectable epidermoid carcinoma of the lung, state T3, N1, N2, or M1.
    Cancer, 1978, Volume: 42, Issue:2

    Topics: Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Neoplasm St

1978
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; C

1976
A structural modification study of procarbazine.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Humans; In Vitro Techniques; Leukemia L121

1979
Rapid development of keratoacanthoma and accelerated transformation into squamous cell carcinoma of the skin: a mutagenic effect of polychemotherapy in a patient with Hodgkin's disease?
    Cancer, 1978, Volume: 41, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Hodgkin Disease; Humans;

1978
Metastatic non-oat-cell bronchogenic carcinoma. Therapy with cyclophosphamide, doxorubicin, methotrexate, and procarbazine (CAMP).
    JAMA, 1978, Dec-15, Volume: 240, Issue:25

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Squamous Cel

1978
[Second neoplasms as a late complication of the treatment of Hodgkin's disease].
    Sangre, 1992, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinom

1992
Secondary uncommon solid neoplasms in cured Hodgkin's disease and follow-up of the original B-DOPA chemotherapy patient group.
    American journal of clinical oncology, 1990, Volume: 13, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Dacarbaz

1990
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1989, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neop

1989
Long-term survivors in metastatic non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Body Wei

1986
CAMP chemotherapy for metastatic non-oat cell bronchogenic carcinoma. A 7-year experience (1975-1981) with 160 patients.
    Cancer, 1985, Nov-15, Volume: 56, Issue:10

    Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Car

1985
Chemotherapy of lung cancer: the experience of the National Cancer Institute of Milan.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Bleomycin; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Doxorubicin; Fluoroura

1973
[Richter's syndrome. 4 cases and an attempt at analysis].
    Acta haematologica, 1973, Volume: 50, Issue:4

    Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Deglutition Disorders; Drug Therapy,

1973
Carcinogenicity of procarbazine.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1974, Volume: 81, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Ear Canal; Ear Neoplasms;

1974
[Prognostic factors in the chemotherapy of bronchial cancers].
    Schweizerische medizinische Wochenschrift, 1974, Feb-23, Volume: 104, Issue:8

    Topics: Adenocarcinoma; Age Factors; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Bronc

1974
Nonlymphomatous malignant tumors complicating Hodgkin's disease. Possible association with intensive therapy.
    The New England journal of medicine, 1972, Nov-30, Volume: 287, Issue:22

    Topics: Adolescent; Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Drug-Related S

1972
An evaluation of combination chemotherapy with procarbazine (NSC-77213) and 5-fluorouracil (NSC-19893) in advanced carcinoma of the lung.
    Cancer chemotherapy reports, 1970, Volume: 54, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Benzoates; Blood Cell Count; Carcinoma; Carcinoma, Bro

1970