procarbazine has been researched along with Carcinoma, Anaplastic in 20 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The national Prostatic Cancer Project has evaluated single and combination chemotherapeutic agents for the treatment of patients with advanced prostatic cancer that has been unresponsive to hormonal therapy." | 3.75 | Chemotherapy of hormonally unresponsive prostatic carcinoma. ( deKernion, JB; Lindner, A, 1984) |
| " Tumours only appeared in those animals in which growth of the granuloma tissue was stimulated with a dose of croton oil." | 3.66 | Single dose carcinogenicity of procarbazine in rats. ( Maier, P; Zbinden, G, 1983) |
| "Two patients developed breast cancer after treatment of Hodgkin's disease." | 1.27 | Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease. ( Anderson, T; Cox, JD; Gillin, M; Greenberg, M; Janjan, NA; Schewe, K; Wilson, JF, 1988) |
| "Two osteosarcomas, an Ewing sarcoma, and a bronchogenic carcinoma were also studied and grew similarly." | 1.26 | Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum. ( Floersheim, GL; Nassenstein, D; Torhorst, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pisarev, MA | 1 |
| Dagrosa, MA | 1 |
| Thomasz, L | 1 |
| Juvenal, G | 1 |
| deKernion, JB | 1 |
| Lindner, A | 1 |
| Zbinden, G | 1 |
| Maier, P | 1 |
| Jacquillat, C | 1 |
| Auclerc, G | 1 |
| Weil, M | 1 |
| Auclerc, MF | 1 |
| Maral, J | 1 |
| Bacci, M | 1 |
| Cavaliere, A | 1 |
| Amorosi, A | 1 |
| Floersheim, GL | 1 |
| Nassenstein, D | 1 |
| Torhorst, J | 1 |
| Pierga, JY | 1 |
| Kalifa, C | 1 |
| Terrier-Lacombe, MJ | 1 |
| Habrand, JL | 1 |
| Lemerle, J | 1 |
| Laing, AH | 2 |
| Berry, RJ | 2 |
| Newman, CR | 2 |
| Smith, P | 1 |
| Muggia, FM | 1 |
| Hansen, HH | 1 |
| Dombernowsky, P | 1 |
| Peto, J | 1 |
| Carl, W | 1 |
| Choi, CH | 1 |
| Carey, RW | 1 |
| Wright, JC | 1 |
| Janjan, NA | 1 |
| Wilson, JF | 1 |
| Gillin, M | 1 |
| Anderson, T | 1 |
| Greenberg, M | 1 |
| Schewe, K | 1 |
| Cox, JD | 1 |
| Deckers, C | 1 |
| Deckers-Passau, L | 1 |
| Maisin, J | 1 |
| Gauthier, JM | 1 |
| Mace, F | 1 |
| Hartwich, G | 1 |
| Alberto, P | 1 |
| Spivack, SD | 1 |
| Eagan, RT | 1 |
| Maurer, LH | 1 |
| Forcier, RJ | 1 |
| Tulloh, M | 1 |
| Gottlieb, JA | 1 |
| Serpick, AA | 1 |
5 reviews available for procarbazine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
[Boron neutron capture therapy applied to undifferentiated thyroid carcinoma].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; | 2006 |
Chemotherapy of hormonally unresponsive prostatic carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cispla | 1984 |
Carcinoma of the choroid plexus: a pediatric experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemotherapy, Adjuvant; Chil | 1993 |
Update in cancer chemotherapy, Part III: Lung cancer, Part 1.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Bleomycin; Carcinoma; C | 1985 |
Drugs 5 years later: procarbazine.
Topics: Animals; Bone Neoplasms; Carcinogens; Carcinoma; Drug Evaluation; Hodgkin Disease; Humans; Lung Neop | 1974 |
3 trials available for procarbazine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Chemotherapy of hormonally unresponsive prostatic carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carmustine; Cispla | 1984 |
Treatment of small-cell carcinoma of bronchus.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Clinical Trials as | 1975 |
Treatment of inoperable carcinoma of bronchus.
Topics: Adenocarcinoma; Administration, Oral; Aged; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell | 1975 |
13 other studies available for procarbazine and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Single dose carcinogenicity of procarbazine in rats.
Topics: Adenoma; Air; Animals; Carcinoma; Croton Oil; Fibrosarcoma; Granuloma; Injections, Intraperitoneal; | 1983 |
[Acute leukemias and solid tumors in the course of Hodgkin disease].
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco | 1983 |
Procarbazine hydrochlorate carcinogenesis in Osborne-Mendel rats.
Topics: Animals; Carcinogens; Carcinoma; Female; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Medi | 1984 |
Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Antilymphocyte Serum; Bone Neoplasms; Carcinoma; Child; | 1980 |
Letter: Treatment of small-cell carcinoma of bronchus.
Topics: Bronchial Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Humans; Mechlorethamine | 1975 |
Cancer chemotherapy and dentistry.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Asparaginase; Carci | 1977 |
Small cell anaplastic carcinoma of lung. Reappraisal of current management.
Topics: Adult; Aged; Carcinoma; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplas | 1976 |
Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Hodgkin | 1988 |
Carcinogenicity of procarbazine.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Ear Canal; Ear Neoplasms; | 1974 |
[Influencing of side-effects of cytostatic drugs using metoclopramide].
Topics: Amides; Anisoles; Antineoplastic Agents; Benzoates; Carcinoma; Ethylamines; Hodgkin Disease; Humans; | 1973 |
[Prognostic factors in the chemotherapy of bronchial cancers].
Topics: Adenocarcinoma; Age Factors; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Bronc | 1974 |
Proceedings: Small cell carcinoma of the lung: staging, paraneoplastic syndromes, treatment, and survival.
Topics: Bone Marrow; Bone Neoplasms; Brain Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination | 1974 |
An evaluation of combination chemotherapy with procarbazine (NSC-77213) and 5-fluorouracil (NSC-19893) in advanced carcinoma of the lung.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Benzoates; Blood Cell Count; Carcinoma; Carcinoma, Bro | 1970 |