procarbazine and Cancer, Second Primary studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

Excerpt	Relevance	Reference
"In the last two decades, it has become evident that secondary leukemias after Hodgkin's disease (HD) are mainly caused by the treatment with alkylating agents, especially mechlorethamine."	9.08	Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. ( Creutzig, U; Gadner, H; Harbott, J; Mann, G; Riepenhausen, M; Ritter, J; Schellong, G, 1997)
"Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose."	7.85	Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017)
" Hodgkin lymphoma survivors who were treated with infradiaphragmatic radiotherapy and/or high-dose procarbazine have an increased risk to develop colorectal cancer."	5.24	Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design. ( Aleman, BM; Bisseling, TM; Bleiker, EM; Carvalho, B; Cats, A; de Boer, JP; Janus, CP; Jóźwiak, K; Lansdorp-Vogelaar, I; Lugtenburg, PJ; Meijer, GA; Moons, LM; Petersen, EJ; Raemaekers, JM; Rigter, LS; Roesink, JM; Snaebjornsson, P; Spaander, MC; Te Riele, H; van der Maazen, RW; van Leerdam, ME; van Leeuwen, FE, 2017)
"In the last two decades, it has become evident that secondary leukemias after Hodgkin's disease (HD) are mainly caused by the treatment with alkylating agents, especially mechlorethamine."	5.08	Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. ( Creutzig, U; Gadner, H; Harbott, J; Mann, G; Riepenhausen, M; Ritter, J; Schellong, G, 1997)
"We report two patients with acute myeloid leukemia (AML) following therapy for malignant glioma; one was a young women treated heavily with alkylating agents for glioblastoma and the other a young man treated with high doses of procarbazine, lomustine, and vincristine (PCV) for anaplastic astrocytoma."	4.80	Acute leukemia following treatment of malignant glioma. ( Brown, MT; Gockerman, JP; Perry, JR, 1998)
"Colorectal cancer surveillance should be considered for HL survivors who received Infradiaphragmatic radiotherapy and a high cumulative procarbazine dose."	3.85	Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. ( Aleman, BM; de Boer, JP; De Bruin, ML; Janus, CP; Kremer, LC; Krol, AD; Louwman, MW; Schaapveld, M; van der Maazen, RW; van Eggermond, AM; van Leerdam, ME; van Leeuwen, FE; Visser, O; Zijlstra, JM, 2017)
" We describe a 5-year-old boy with stage IV HD, successfully treated with MOPP (mechlorethamine, vincristine, procarbazine, and prednisone)/ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy followed by 35 Gy mantle radiotherapy who developed primary hyperparathyroidism because of benign PTA at the age of 20 years, and died of CS in thoracic vertebrae at the age of 22 years."	3.76	Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease. ( Albayrak, M; Coskun, U; Gursel, T; Kaya, Z; Keskin, EY; Kocak, U; Uluoglu, O, 2010)
"Between 1978 and 1988, 20 children with medulloblastoma (MB) of the brain were treated postoperatively with MOPP (nitrogen mustard, vincristine, prednisone, and procarbazine)."	3.68	Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. ( Hayani, A; Mahoney, DH; Taylor, LD, 1992)
"The causes of death were Hodgkin's lymphoma in 36 patients, second neoplasms in 12, cardiorespiratory diseases in 4, pulmonary diseases in 2, and unknown in 6."	2.72	MOPPEBVCAD chemotherapy with limited and conditioned radiotherapy in advanced Hodgkin's lymphoma: 10-year results, late toxicity, and second tumors. ( Broglia, C; Cavanna, L; Chisesi, T; Corazza, GR; Corbella, F; Federico, M; Gobbi, PG; Iannitto, E; La Sala, A; Levis, A; Molica, S; Pavone, V; Sacchi, S; Valentino, F, 2006)
"In early-stage Hodgkin's lymphoma (HL), subtotal nodal irradiation (STNI) and combined chemotherapy/radiotherapy produce high disease control rates but also considerable late toxicity."	2.72	Combined-modality therapy for clinical stage I or II Hodgkin's lymphoma: long-term results of the European Organisation for Research and Treatment of Cancer H7 randomized controlled trials. ( Aleman, BM; Bosq, J; Carde, P; Dupouy, N; Eghbali, H; Girinsky, T; Hagenbeek, A; Henry-Amar, M; Kluin-Nelemans, JC; Krol, AD; Monconduit, M; Noordijk, EM; Pény, AM; Raemaekers, JM; Thomas, J; Tirelli, U; Verschueren, TA; Vovk, M, 2006)
"Two cases developed a second malignancy."	2.68	Treatment of childhood Hodgkin's disease without radiotherapy. ( Behrendt, H; van den Berg, H; Zsiros, J, 1997)
"The majority of patients with advanced Hodgkin's lymphoma are cured with currently available therapy, such as ABVD (Adriamycin [doxorubicin], bleomycin, vinblastine, and dacarbazine)."	2.44	Is BEACOPP better than ABVD? ( Cheson, BD, 2007)
"We reviewed all reported cases of Burkitt's lymphoma and/or Burkitt's leukemia (BLL) occurring following therapy for Hodgkin's disease."	2.39	Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease. ( Cooper, DL; Levy, A; Salloum, E; Tallini, G, 1996)
"80% or more of patients suffering from Hodgkin's lymphoma (HD) of limited stage are cured with modern treatment."	2.39	[Current therapy concepts in early and intermediate stages of Hodgkin diseases in adults]. ( Glanzmann, C; Stahel, R, 1995)
"Thoracic and abdominal irradiation for Hodgkin's disease was performed concomitantly with chemotherapy for the non-Hodgkin's lymphoma."	2.38	Cerebral non-Hodgkin's lymphoma discovered when treating Hodgkin's disease. ( Bergeron, C; Chatel, M; Darcel, F; Edan, C; Faivre, J; Jouan, H; Le Moine, P; Le Prise-Fleury, E; Patte, C; Tass, P, 1993)
"Patients who survive Hodgkin lymphoma (HL) are at increased risk of secondary neoplasms (SNs)."	1.43	Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases. ( Çavdar, A; Ceyhan, K; Deda, H; Gökçora, İH; Gözdaşoğlu, S; Işıkman, E; Pamir, A; Taçyıldız, N; Uluoğlu, Ö; Ünal, E; Yavuz, G, 2016)
"Therapy-related acute myeloid leukemia and myelodysplastic syndromes (t-AML/MDS) represent severe late effects in patients treated for Hodgkin lymphoma (HL)."	1.40	Therapy-related acute myeloid leukemia and myelodysplastic syndromes in patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group. ( Behringer, K; Böll, B; Borchmann, P; Diehl, V; Eichenauer, DA; Engert, A; Franklin, J; Fuchs, M; Halbsguth, T; Haverkamp, H; Klimm, B; Rothe, A; Sasse, S; Thielen, I; von Tresckow, B, 2014)
"To quantify the incidence of thyroid cancer after Hodgkin lymphoma (HL) and determine disease characteristics, risk factors, and treatment outcomes."	1.40	Thyroid malignancies in survivors of Hodgkin lymphoma. ( Chen, YH; Marcus, KJ; Michaelson, EM; Ng, AK; Silver, B; Stevenson, MA; Tishler, RB, 2014)
"To assess therapy-related acute myeloid leukemia/myelodysplastic syndrome (t-AML/MDS) risk in patients treated for Hodgkin lymphoma (HL) on successive generations of Stanford clinical trials."	1.39	Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials. ( Advani, RH; Balise, R; Greenberg, PL; Hoppe, RT; Horning, SJ; Koontz, MZ; Rosenberg, SA, 2013)
"Ductal invasive carcinoma and ductal carcinoma in situ represented, respectively, 51 cases (71%) and 14 cases (19%)."	1.38	Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option. ( Belin, L; Bollet, MA; Campana, F; Decaudin, D; Fourquet, A; Haberer, S; Kirova, YM; Le Scodan, R; Moisson, P; Pierga, JY; Reyal, F; Savignoni, A; Stevens, D, 2012)
"The SIR for colorectal cancer was 4."	1.38	Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study. ( Armstrong, GT; Constine, LS; Crotty, C; Diller, L; Hammond, S; Henderson, TO; Inskip, P; Leisenring, W; Meadows, A; Nathan, PC; Neglia, J; Oeffinger, KC; Robison, LL; Rubin, DT; Smith, SA; Stovall, M; Whitton, J, 2012)
" Primary therapies were divided into four groups: radiotherapy alone, moderately dosed COPP/ABVD-like chemotherapies for intermediate and advanced stages and BEACOPP escalated."	1.37	Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. ( Diehl, V; Engert, A; Franklin, J; Hasenclever, D; Josting, A; Loeffler, M; Scholz, M, 2011)
"The behavior of Hodgkin's lymphoma (HL) is different in developing countries, perhaps due to differences in epidemiology and population access to health care."	1.35	Comparison between hybrid MOPPABV and ABVD chemotherapy protocols for Hodgkin's lymphoma in public hospitals of the largest South American city: a retrospective 14-year study. ( Alves, AC; Baiocchi, OC; Oliveira, JS; Souza, EM; Zanichelli, MA, 2009)
"The risk of stomach cancer was 3."	1.35	Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy. ( Aleman, BM; Besseling, G; de Bruin, ML; de Wit, R; Gietema, JA; Hauptmann, M; Kerst, JM; Noordijk, EM; Ribot, JG; van 't Veer, MB; van den Belt-Dusebout, AW; van Leeuwen, FE, 2009)
"The treatment strategies of Hodgkin's lymphoma (HL) are different according to clinical stage and risk factors, yet the optimal treatment strategy remains unclear."	1.34	[Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases]. ( Hu, DS; Hu, S; Song, QB; Tan, WY; Wei, L; Zeng, FY; Zhou, LQ, 2007)
"Actuarial risk of second malignancy for adolescents and adults was not different (P = ."	1.33	Hodgkin's lymphoma in adolescents. ( Connors, JM; Foltz, LM; Song, KW, 2006)
"We consider as second cancer all tumours other than HD observed in patients after treatment for HD."	1.32	[Second malignancies following Hodgkin's disease treatment in Tunisia. Retrospective study of 26 cases observed at the institute Salah-Azaïz]. ( Belhaj Ali, Z; Benna, F; Besbes, M; Bouaouina, N; Boussen, H; Gammoudi, A; Ghilen, L; Kochbati, L; Maalej, M; Rahal, K, 2003)
"Risk of lung cancer was borderline significantly greater in patients treated with mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) chemotherapy than those who did not receive this treatment (relative risk [RR] = 1."	1.31	Lung cancer after Hodgkin's disease: a nested case-control study of the relation to treatment. ( Allerton, R; Barber, JA; Cunningham, D; Horwich, A; Linch, DC; Lister, TA; Rohatiner, AZ; Schoemaker, MJ; Swerdlow, AJ; Vaughan Hudson, G; Williams, MV, 2001)
"Patients with neurofibromatosis type 1 (NF1) often have gliomas as a complication, most of which are benign pilocytic astrocytomas which have arisen in optic pathways."	1.31	Neurofibromatosis type 1-associated unusual pleomorphic astrocytoma displaying continual malignant progression. ( Hirato, J; Kamiya, M; Kurachi, H; Nakazato, Y; Sasaki, A; Yokoo, H, 2001)
"The majority of second cancers arise within or next to the irradiated portals, and particular attention should be paid to the irradiated sites in posttreatment follow-up."	1.30	Second cancer among long-term survivors from Hodgkin's disease. ( Joensuu, H; Muhonen, T; Nyandoto, P, 1998)
"Patients treated for Hodgkin's disease have an increased risk of developing subsequent acute leukemia."	1.30	The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con ( Anselmo, AP; Baroni, CD; Bernasconi, C; Brusamolino, E; Klersy, C; Lazzarino, M; Lunghi, F; Mandelli, F; Maurizi-Enrici, R; Orlandi, E; Pagnucco, G; Santoro, M, 1998)
"Hodgkin's disease is curable in the majority of patients, although a proportion of patients are resistant to or relapse after initial therapy."	1.30	High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML. ( Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D, 1999)
"The relative risk of second cancers overall was 27."	1.30	Second malignancy in patients with Hodgkin's disease treated at the Royal Marsden Hospital. ( Barber, JA; Cunningham, D; Horwich, A; Milan, S; Omar, RZ; Swerdlow, AJ, 1997)
"In this series, risk factors for second cancer were age >/=40 years (RR = 3."	1.30	Treatment-related deaths and second cancer risk after autologous stem-cell transplantation for Hodgkin's disease. ( André, M; Attal, M; Bastion, Y; Blaise, D; Cahn, JY; Colombat, P; Fermé, C; Fleury, J; Gisselbrecht, C; Henry-Amar, M; Kuentz, M; Milpied, N; Nedellec, G; Pico, JL, 1998)
"The risk of second cancer was analyzed (1) relative to the general population and (2) between risk subgroups using the Cox proportional hazards model."	1.29	Second primary cancers in patients continuously disease-free from Hodgkin's disease: a protective role for the spleen? ( Bodis, S; Bosq, J; Cosset, JM; Dietrich, PY; Hayat, M; Henry-Amar, M, 1994)
"Thirteen patients have died of their second malignancy, including two of a third malignancy, while four have been followed for less than one year."	1.29	Second malignant neoplasms in patients with Hodgkin's disease. ( Atkinson, CH; Colls, BM; Fitzharris, BM; Robinson, BA, 1994)
"Two patients developed breast cancer 14 and 8 years after treatment of Hodgkin's disease."	1.29	Breast cancer developing after therapy for Hodgkin's disease. ( Cascinu, S; Catalano, G; Fedeli, A, 1993)
"A case of Hodgkin's disease with isolated cerebral relapse is reported here."	1.29	Meningioma-like cerebral relapse of Hodgkin's disease. ( Catarini, M; Discepoli, G; Leoni, P; Montillo, M; Rychlicki, F; Scarpelli, M, 1994)
"The occurrence of HIV associated non-Hodgkin's lymphoma (NHL) is a well recognized event."	1.29	Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. ( Brody, J; Goh, JC; Kaplan, MH; Koduru, P; Lichtman, SM; Susin, M, 1993)
"We report a 54-year-old patient with Hodgkin's disease who achieved a complete remission after combined modality treatment."	1.29	Factor VIII inhibitor prior to and during secondary acute nonlymphocytic leukemia in a patient with cured Hodgkin's disease. ( Bendandi, M; Cantagalli, F; Macchi, S; Mancino, A; Simoncelli, F; Stefanati, V; Tura, S; Visani, G; Zaccaria, A; Zinzani, PL, 1995)
"In patients with advanced Hodgkin's disease (HD), the alternation of MOPP with ABVD or hybrid MOPP/ABVD are associated with a high CR rate and a high probability of 5-year survival."	1.29	Hybrid MOPP/ABVD and radiotherapy in advanced Hodgkin's disease. ( Aversa, S; Bianco, A; Chiarion Sileni, V; Fiorentino, MV; Mazzarotto, R; Pappagallo, GL; Salvagno, L; Scarzello, G; Sorarù, M; Sotti, G, 1995)
"Two cases of malignant schwannoma are reported 13 and 15 years following combined modality treatment for Hodgkin's disease."	1.29	Malignant schwannoma following treatment for Hodgkin's disease. ( Bridges, LR; Cartwright, SC; Dodwell, DJ; Fisher, PM; Stone, J, 1994)
"2) Non-Hodgkin's lymphoma has not appeared in any of the patients in this series."	1.28	[Second neoplasms as a late complication of the treatment of Hodgkin's disease]. ( Alvarez, A; Colomé, JA; del Potro, E; Díaz Mediavilla, J; González, FA; Martínez, R; Morales, MD; Villegas, A, 1992)
"20 untreated Hodgkin's disease patients and 1 patient relapsing after radiotherapy (17 stage IIB-IV and 4 stage I-IIA) were given doxorubicin, bleomycin, etoposide and prednisone on a 21-day cycle."	1.28	ABEP as primary chemotherapy for Hodgkin's disease. ( Alberto, P; Mermillod, B; Zulian, GB, 1992)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	41 (44.09)	18.2507
2000's	32 (34.41)	29.6817
2010's	18 (19.35)	24.3611
2020's	2 (2.15)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Non Randomized, Multicenter, Prospective Pediatric Hodgkin Lymphoma Treatment Trial Stratified According to Initial Risk Factors and Response to Chemotherapy, Reduced Cumulative Doses of Antineoplastic Agents and Radiotherapy.[NCT03500133]	Phase 4	500 participants (Anticipated)	Interventional	2017-10-06	Recruiting
Phase III Randomized Trial of Adjuvant Involved-Field Radiotherapy vs No Adjuvant Therapy Following Remission Induction With MOPP/ABV Hybrid Chemotherapy in Patients With Stage III/IV Hodgkin's Disease[NCT00002462]	Phase 3	615 participants (Actual)	Interventional	1989-09-30	Active, not recruiting
Evaluation of Late Treatment Effects in Long-Term Survivors of Hodgkin's Disease Previously Treated at NIH: A Multi-Institutional Trial[NCT00924131]		157 participants (Anticipated)	Observational	2009-04-17	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Long-term overall survival and toxicities of ABVD vs BEACOPP in advanced Hodgkin lymphoma: A pooled analysis of four randomized trials. Cancer medicine, 2020, Volume: 9, Issue:18 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials,	2020
Limited-stage Hodgkin lymphoma: optimal chemotherapy and the role of radiotherapy. American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2013 Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinic	2013
Is BEACOPP better than ABVD? Current hematologic malignancy reports, 2007, Volume: 2, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamid	2007
Will BEACOPP be the standard for high risk Hodgkin lymphoma patients in advanced stages? Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2007, Volume: 37, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamid	2007
[Current therapy concepts in early and intermediate stages of Hodgkin diseases in adults]. Praxis, 1995, Oct-10, Volume: 84, Issue:41 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined	1995
Cerebral non-Hodgkin's lymphoma discovered when treating Hodgkin's disease. Medical and pediatric oncology, 1993, Volume: 21, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Carmustine; Cyc	1993
Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease. Cancer investigation, 1996, Volume: 14, Issue:6 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Cyclophosphamide	1996
[Outcome of 70 patients diagnosed with Hodgkin's disease after first-line and salvage treatment: experience at one center]. Sangre, 1998, Volume: 43, Issue:3 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Combined	1998
Acute leukemia following treatment of malignant glioma. Journal of neuro-oncology, 1998, Volume: 40, Issue:1 Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Fatal Outcome	1998
Problems in Hodgkin's disease management. Blood, 1999, Feb-01, Volume: 93, Issue:3 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant	1999
The use of combination chemotherapy in the treatment of early stage Hodgkin's disease. Important advances in oncology, 1992 Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality	1992

Article	Year
Long-Term Follow-Up of Contemporary Treatment in Early-Stage Hodgkin Lymphoma: Updated Analyses of the German Hodgkin Study Group HD7, HD8, HD10, and HD11 Trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Jun-20, Volume: 35, Issue:18 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	2017
Long-Term Results of the HD2000 Trial Comparing ABVD Versus BEACOPP Versus COPP-EBV-CAD in Untreated Patients With Advanced Hodgkin Lymphoma: A Study by Fondazione Italiana Linfomi. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Apr-10, Volume: 34, Issue:11 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazin	2016
Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design. BMC cancer, 2017, Feb-07, Volume: 17, Issue:1 Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Protocols; Colonoscopy; Colo	2017
Randomized comparison of low-dose involved-field radiotherapy and no radiotherapy for children with Hodgkin's disease who achieve a complete response to chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Sep-15, Volume: 20, Issue:18 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschoo	2002
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease. The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclopho	2003
Involved-field radiotherapy for advanced Hodgkin's lymphoma. The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	2003
MOPPEBVCAD chemotherapy with limited and conditioned radiotherapy in advanced Hodgkin's lymphoma: 10-year results, late toxicity, and second tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jan-15, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	2006
Long-term results and competing risk analysis of the H89 trial in patients with advanced-stage Hodgkin lymphoma: a study by the Groupe d'Etude des Lymphomes de l'Adulte (GELA). Blood, 2006, Jun-15, Volume: 107, Issue:12 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Com	2006
Combined-modality therapy for clinical stage I or II Hodgkin's lymphoma: long-term results of the European Organisation for Research and Treatment of Cancer H7 randomized controlled trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jul-01, Volume: 24, Issue:19 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	2006
Involved-field radiotherapy for patients in partial remission after chemotherapy for advanced Hodgkin's lymphoma. International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	2007
Extended-field radiotherapy in favorable stage IA-IIA Hodgkin's disease (prognostic role of stage). International journal of radiation oncology, biology, physics, 1994, Nov-15, Volume: 30, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	1994
Treatment of childhood Hodgkin's disease without radiotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8 Suppl 1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Combined Modality Ther	1997
Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:6 Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child	1997
Are ABVD and MOPP/ABV truly equivalent for treating Hodgkin's disease at advanced stages? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Disease-Free Survival; Doxor	1998
Moderate dose escalation for advanced stage Hodgkin's disease using the bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone scheme and adjuvant radiotherapy: a study of the German Hodgkin's Lymphoma Study Group. Blood, 1998, Dec-15, Volume: 92, Issue:12 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dose	1998
Cyclophosphamide-based, seven-drug hybrid and low-dose involved field radiation for the treatment of childhood and adolescent Hodgkin disease. Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Combined Modality Ther	2001
ChlVPP/EVA hybrid versus the weekly VAPEC-B regimen for previously untreated Hodgkin's disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jul-01, Volume: 20, Issue:13 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cy	2002
The use of combination chemotherapy in the treatment of early stage Hodgkin's disease. Important advances in oncology, 1992 Topics: Actuarial Analysis; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality	1992

Article	Year
Small lymphocytic lymphoma secondary to young patient with a history of classical Hodgkin Lymphoma. International journal of laboratory hematology, 2022, Volume: 44, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Dox	2022
Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors. British journal of cancer, 2017, Jul-25, Volume: 117, Issue:3 Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colon; Colo	2017
Therapy-related acute myeloid leukemia and myelodysplastic syndromes in patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group. Blood, 2014, Mar-13, Volume: 123, Issue:11 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide	2014
Thyroid malignancies in survivors of Hodgkin lymphoma. International journal of radiation oncology, biology, physics, 2014, Mar-01, Volume: 88, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc	2014
Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases. Turkish journal of haematology : official journal of Turkish Society of Haematology, 2016, Mar-05, Volume: 33, Issue:1 Topics: Adenoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Du	2016
Lung cancer and other second neoplasms after treatment of Hodgkin lymphoma. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2016, Volume: 18, Issue:1 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Dox	2016
High-Risk, Advanced-Stage Hodgkin Lymphoma: The Impact of Combined Escalated BEACOPP and ABVD Treatment in Patients Who Rapidly Achieve Metabolic Complete Remission on Interim FDG-PET/CT Scan. Acta haematologica, 2016, Volume: 135, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici	2016
Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma. International journal of radiation oncology, biology, physics, 2017, 01-01, Volume: 97, Issue:1 Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy	2017
Comparison between hybrid MOPPABV and ABVD chemotherapy protocols for Hodgkin's lymphoma in public hospitals of the largest South American city: a retrospective 14-year study. Annals of hematology, 2009, Volume: 88, Issue:7 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brazil; Dacarbaz	2009
Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy. International journal of radiation oncology, biology, physics, 2009, Dec-01, Volume: 75, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cohort Studies; Combine	2009
Radiation-induced glioblastoma occurring 35 years after radiation therapy for medulloblastoma: case report. Brain tumor pathology, 2010, Volume: 27, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Glioblastoma; Humans; M	2010
Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:3 Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine	2011
Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease. Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:7 Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child, Preschool; Chondrosarcoma	2010
Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option. International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms	2012
Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study. Annals of internal medicine, 2012, Jun-05, Volume: 156, Issue:11 Topics: Adolescent; Adult; Antineoplastic Agents; Canada; Child; Colorectal Neoplasms; Gastrointestinal Neop	2012
Summaries for patients. Increased risk for gastrointestinal cancer in childhood cancer survivors. Annals of internal medicine, 2012, Jun-05, Volume: 156, Issue:11 Topics: Adolescent; Adult; Antineoplastic Agents; Canada; Child; Colorectal Neoplasms; Gastrointestinal Neop	2012
Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Feb-10, Volume: 31, Issue:5 Topics: Academic Medical Centers; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Californ	2013
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study. Blood, 2003, Mar-01, Volume: 101, Issue:5 Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth	2003
Hodgkin's disease--clinical trials and travails. The New England journal of medicine, 2003, Jun-12, Volume: 348, Issue:24 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclophosphami	2003
Radiation therapy in the treatment of Hodgkin's disease--do you see what I see? Journal of the National Cancer Institute, 2003, Jul-02, Volume: 95, Issue:13 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Chemotherapy, Adjuvant;	2003
[Second malignancies following Hodgkin's disease treatment in Tunisia. Retrospective study of 26 cases observed at the institute Salah-Azaïz]. Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2003, Volume: 7, Issue:5 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Dacarbazine; Do	2003
ChlVPP/ABVVP, a first line 'hybrid' combination chemotherapy for advanced Hodgkin's lymphoma: a retrospective analysis. British journal of haematology, 2004, Volume: 125, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Di	2004
Combination chemotherapy plus low-dose involved-field radiotherapy for early clinical stage Hodgkin's lymphoma. International journal of radiation oncology, biology, physics, 2004, Jul-01, Volume: 59, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemothera	2004
[A case of secondary non-Hodgkin's lymphoma of the colon after the treatment for Hodgkin's disease]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2005, Volume: 102, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Therapy;	2005
Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease. Cancer genetics and cytogenetics, 2005, Volume: 159, Issue:1 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Chromosome	2005
Survival in Hodgkin's disease patients--report of 25 years of experience at the Milan Cancer Institute. European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:7 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Dacarbazine; Disea	2005
Occurrence of multiple myeloma 13 years after Hodgkin's disease: chance or consequence? Annals of hematology, 2005, Volume: 84, Issue:12 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carmustine; Combined Modality	2005
Benign pleural schwannoma secondary to radiotherapy for Hodgkin disease. American journal of clinical oncology, 2005, Volume: 28, Issue:6 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Basal Cell; Combin	2005
Hodgkin's lymphoma in adolescents. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-01, Volume: 24, Issue:16 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; British Columbia; Chem	2006
Long-term outcome in children with Hodgkin's lymphoma: the United Kingdom Children's Cancer Study Group HD82 trial. European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:7 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chlorambucil; D	2007
[Treatment results of stage IA Hodgkin lymphoma: a report of 97 cases]. Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Co	2007
Early-stage Hodgkin's disease: long-term results with radiotherapy alone or combined radiotherapy and chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Combin	1994
Hybrid MOPP/ABVD and radiotherapy in advanced Hodgkin's disease. Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:2 Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc	1995
Factor VIII inhibitor prior to and during secondary acute nonlymphocytic leukemia in a patient with cured Hodgkin's disease. Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6 Topics: Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Transfusion; Combined Modality	1995
Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. Leukemia & lymphoma, 1993, Volume: 9, Issue:4-5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Dexametha	1993
Peripheral T-cell non-Hodgkin's lymphoma following treatment of nodular lymphocyte predominance Hodgkin's disease. Archives of pathology & laboratory medicine, 1995, Volume: 119, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Lymphocytes; Lymphoma, B-Ce	1995
Meningioma-like cerebral relapse of Hodgkin's disease. Leukemia & lymphoma, 1994, Volume: 14, Issue:1-2 Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fatal Outcome; Female; Ho	1994
Second malignant neoplasms in patients with Hodgkin's disease. Australian and New Zealand journal of medicine, 1994, Volume: 24, Issue:4 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Moda	1994
Second primary cancers in patients continuously disease-free from Hodgkin's disease: a protective role for the spleen? Blood, 1994, Aug-15, Volume: 84, Issue:4 Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modal	1994
Malignant schwannoma following treatment for Hodgkin's disease. Clinical oncology (Royal College of Radiologists (Great Britain)), 1994, Volume: 6, Issue:3 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Female	1994
Breast cancer developing after therapy for Hodgkin's disease. Clinical oncology (Royal College of Radiologists (Great Britain)), 1993, Volume: 5, Issue:1 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intr	1993
Second malignant tumours in childhood Hodgkin's disease. Medical and pediatric oncology, 1996, Volume: 26, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Protocols; Cohort	1996
Therapy-related leukemia with a novel 21q22 rearrangement. Cancer genetics and cytogenetics, 1996, Volume: 90, Issue:1 Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosomes, Human, Pair 21;	1996
Chemotherapy-induced non-Hodgkin's lymphoma in a patient with Hodgkin's disease--a case report. JPMA. The Journal of the Pakistan Medical Association, 1996, Volume: 46, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bleomycin; Cyclophosphamide; D	1996
Second malignancy in patients with Hodgkin's disease treated at the Royal Marsden Hospital. British journal of cancer, 1997, Volume: 75, Issue:1 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protoc	1997
Detection of a dormant 20q- leukemia clone in bone marrow cultures with hematopoietic growth factors: implications for secondary leukemia post-transplant. Bone marrow transplantation, 1997, Volume: 19, Issue:5 Topics: Acute Disease; Adult; Anemia, Refractory, with Excess of Blasts; Antimetabolites, Antineoplastic; An	1997
A cure model with time-changing risk factor: an application to the analysis of secondary leukaemia. A report from the International Database on Hodgkin's Disease. Statistics in medicine, 1998, Jan-15, Volume: 17, Issue:1 Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Fr	1998
The clonal relationship between nodular sclerosis Hodgkin's disease with a clonal Reed-Sternberg cell population and a subsequent B-cell small noncleaved cell lymphoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1998, Volume: 11, Issue:5 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Combined Modality Therapy; Cycloph	1998
Treatment-related deaths and second cancer risk after autologous stem-cell transplantation for Hodgkin's disease. Blood, 1998, Sep-15, Volume: 92, Issue:6 Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Female; Hematopoietic Stem	1998
Second cancer among long-term survivors from Hodgkin's disease. International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2 Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bleom	1998
Hodgkin's disease and the risk of acute leukemia in successfully treated patients. Haematologica, 1998, Volume: 83, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Dacarbazine; D	1998
The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con Haematologica, 1998, Volume: 83, Issue:9 Topics: Abdomen; Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over;	1998
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma. Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6 Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberra	1998
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML. British journal of cancer, 1999, Volume: 81, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine;	1999
Early occurrence of a secondary thyroid carcinoma in a child treated for Hodgkin disease. Medical and pediatric oncology, 2001, Volume: 36, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Papillary; Chemotherapy, Adjuvant; Child;	2001
Lung cancer after Hodgkin's disease: a nested case-control study of the relation to treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Mar-15, Volume: 19, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Female; Hodgkin D	2001
The risk of second malignant tumors and its consequences for the overall survival of Hodgkin's disease patients and for the choice of their treatment at presentation: analysis of a series of 1524 cases consecutively treated at the Florence University Hosp International journal of radiation oncology, biology, physics, 2001, Apr-01, Volume: 49, Issue:5 Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Confidence Intervals; F	2001
Neurofibromatosis type 1-associated unusual pleomorphic astrocytoma displaying continual malignant progression. Pathology international, 2001, Volume: 51, Issue:7 Topics: Adolescent; Antigens, Nuclear; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biomarke	2001
Transformation of Hodgkin's disease to high-grade B-cell lymphoma: remission after Rituximab monotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:8 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti	2001
[Second neoplasms as a late complication of the treatment of Hodgkin's disease]. Sangre, 1992, Volume: 37, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinom	1992
Hodgkin's disease and acute leukemia. Is it a true association? Archives of medical research, 1992,Spring, Volume: 23, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil	1992
Management of stage II Hodgkin's disease: 15 years experience at St. Bartholomew's Hospital. Annals of oncology : official journal of the European Society for Medical Oncology, 1992, Volume: 3, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit	1992
ABEP as primary chemotherapy for Hodgkin's disease. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:10 Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabin	1992
Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. Journal of neuro-oncology, 1992, Volume: 14, Issue:1 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool	1992
Carcinoma of the duodenum after trauma, radiotherapy and chemotherapy. The Netherlands journal of surgery, 1991, Volume: 43, Issue:5 Topics: Abdominal Injuries; Adenocarcinoma; Combined Modality Therapy; Duodenal Neoplasms; Hodgkin Disease;	1991

procarbazine and Cancer, Second Primary

Research Excerpts

Research

Studies (93)

Authors

Clinical Trials (3)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
André, MPE	1
Carde, P	3
Viviani, S	3
Bellei, M	1
Fortpied, C	1
Hutchings, M	1
Gianni, AM	2
Brice, P	2
Casasnovas, O	2
Gobbi, PG	3
Zinzani, PL	2
Dupuis, J	1
Iannitto, E	2
Rambaldi, A	1
Brière, J	1
Clément-Filliatre, L	1
Heczko, M	1
Valagussa, P	3
Douxfils, J	1
Depaus, J	1
Federico, M	3
Mounier, N	2
Yan, J	1
Cui, F	1
Zhao, S	1
Sasse, S	2
Bröckelmann, PJ	1
Goergen, H	1
Plütschow, A	1
Müller, H	1
Kreissl, S	1
Buerkle, C	1
Borchmann, S	1
Fuchs, M	3
Borchmann, P	2
Diehl, V	6
Engert, A	4
van Eggermond, AM	1
Schaapveld, M	1
Janus, CP	2
de Boer, JP	2
Krol, AD	2
Zijlstra, JM	1
van der Maazen, RW	4
Kremer, LC	1
van Leerdam, ME	2
Louwman, MW	1
Visser, O	1
De Bruin, ML	2
Aleman, BM	6
van Leeuwen, FE	3
Bartlett, NL	1
Eichenauer, DA	1
Thielen, I	1
Haverkamp, H	1
Franklin, J	4
Behringer, K	1
Halbsguth, T	1
Klimm, B	1
Rothe, A	1
Böll, B	1
von Tresckow, B	1
Michaelson, EM	1
Chen, YH	1
Silver, B	1
Tishler, RB	1
Marcus, KJ	1
Stevenson, MA	1
Ng, AK	1
Gözdaşoğlu, S	1
Pamir, A	1
Ünal, E	1
Gökçora, İH	1
Uluoğlu, Ö	2
Ceyhan, K	1
Deda, H	1
Işıkman, E	1
Yavuz, G	1
Taçyıldız, N	1
Çavdar, A	1
Almagro-Casado, E	1
Sánchez, A	1
Cantos, B	1
Salas, C	1
Pérez-Callejo, D	1
Provencio, M	1
Kedmi, M	1
Apel, A	1
Davidson, T	1
Levi, I	1
Dann, EJ	1
Polliack, A	1
Ben-Bassat, I	1
Nagler, A	2
Avigdor, A	1
Merli, F	1
Luminari, S	1
Cascavilla, N	1
Mammi, C	1
Ilariucci, F	1
Stelitano, C	1
Musso, M	1
Baldini, L	1
Galimberti, S	1
Angrilli, F	1
Polimeno, G	1
Scalzulli, PR	1
Ferrari, A	1
Marcheselli, L	1
Conway, JL	1
Connors, JM	2
Tyldesley, S	1
Savage, KJ	1
Campbell, BA	1
Zheng, YY	1
Hamm, J	1
Pickles, T	1
Rigter, LS	1
Spaander, MC	1
Moons, LM	1
Bisseling, TM	1
Lugtenburg, PJ	2
Petersen, EJ	1
Roesink, JM	1
Raemaekers, JM	4
Cats, A	1
Bleiker, EM	1
Snaebjornsson, P	1
Carvalho, B	1
Lansdorp-Vogelaar, I	1
Jóźwiak, K	1
Te Riele, H	1
Meijer, GA	1
Souza, EM	1
Baiocchi, OC	1
Zanichelli, MA	1
Alves, AC	1
Oliveira, JS	1
van den Belt-Dusebout, AW	1
Besseling, G	1
Hauptmann, M	1
van 't Veer, MB	2
de Wit, R	1
Ribot, JG	1
Noordijk, EM	2
Kerst, JM	1
Gietema, JA	1
Hamasaki, K	1
Nakamura, H	1
Ueda, Y	1
Makino, K	1
Kuratsu, J	1
Cheson, BD	1
Scholz, M	1
Josting, A	1
Hasenclever, D	3
Loeffler, M	4
Keskin, EY	1
Gursel, T	1
Albayrak, M	1
Kaya, Z	1
Coskun, U	1
Kocak, U	1
Haberer, S	1
Belin, L	1
Le Scodan, R	1
Kirova, YM	1
Savignoni, A	1
Stevens, D	1
Moisson, P	1
Decaudin, D	1
Pierga, JY	1
Reyal, F	1
Campana, F	1
Fourquet, A	1
Bollet, MA	1
Henderson, TO	2
Oeffinger, KC	2
Whitton, J	2
Leisenring, W	2
Neglia, J	2
Meadows, A	2
Crotty, C	2
Rubin, DT	2
Diller, L	2
Inskip, P	2
Smith, SA	2
Stovall, M	2
Constine, LS	2
Hammond, S	2
Armstrong, GT	2
Robison, LL	2
Nathan, PC	2
Koontz, MZ	1
Horning, SJ	1
Balise, R	1
Greenberg, PL	1
Rosenberg, SA	1
Hoppe, RT	1
Advani, RH	1
Nachman, JB	1
Sposto, R	1
Herzog, P	1
Gilchrist, GS	1
Wolden, SL	1
Thomson, J	1
Kadin, ME	1
Pattengale, P	1
Davis, PC	1
Hutchinson, RJ	1
White, K	1
Metayer, C	1
Curtis, RE	1
Vose, J	1
Sobocinski, KA	1
Horowitz, MM	1
Bhatia, S	1
Fay, JW	1
Freytes, CO	1
Goldstein, SC	1
Herzig, RH	1
Keating, A	1
Miller, CB	1
Nevill, TJ	1
Pecora, AL	1
Rizzo, JD	1
Williams, SF	1
Li, CY	1
Travis, LB	1
Weisdorf, DJ	1
DeVita, VT	2
Pfreundschuh, M	2
Lathan, B	2
Paulus, U	1
Tesch, H	2
Herrmann, R	1
Dörken, B	1
Müller-Hermelink, HK	1
Dühmke, E	1
Tirelli, U	2
Bortolus, R	2
Lybeert, ML	2
Keuning, JJ	1
Girinsky, T	3
Tomsic, R	1
Vovk, M	2
van Hoof, A	1
Demeestere, G	2
Thomas, J	2
Schroyens, W	1
De Boeck, K	1
Baars, JW	1
Kluin-Nelemans, JC	2
Carrie, C	1
Aoudjhane, M	1
Bron, D	1
Eghbali, H	2
Smit, WG	1
Meerwaldt, JH	2
Hagenbeek, A	2
Pinna, A	2
Henry-Amar, M	5
Longo, DL	2
Kochbati, L	1
Boussen, H	1
Benna, F	1
Belhaj Ali, Z	1
Gammoudi, A	1
Bouaouina, N	1
Besbes, M	1
Ghilen, L	1
Rahal, K	1
Maalej, M	1
Martinelli, G	1
Cocorocchio, E	1
Peccatori, F	1
Zucca, E	1
Saletti, PC	1
Calabrese, L	1
Pastano, R	1
Pruneri, G	1
Mazzetta, C	1
Ghielmini, M	1
Cavalli, F	1
Vassilakopoulos, TP	1
Angelopoulou, MK	1
Siakantaris, MP	1
Kontopidou, FN	1
Dimopoulou, MN	1
Kokoris, SI	1
Kyrtsonis, MC	1
Tsaftaridis, P	1
Karkantaris, C	1
Anargyrou, K	1
Boutsis, DE	1
Variamis, E	1
Michalopoulos, T	1
Boussiotis, VA	1
Panayiotidis, P	1
Papavassiliou, C	1
Pangalis, GA	1
Yamamoto, R	1
Hashiguchi, K	1
Iwai, A	1
Satoh, S	1
Hanaoka, N	1
Okudaira, K	1
Inoue, T	1
Miyazaki, J	1
Matsuzaki, K	1
Tsuzuki, Y	1
Kawaguchi, A	1
Nagao, S	1
Itoh, K	1
Miura, S	1
Hatano, B	1
Kneller, A	1
Cohen, N	1
Berkowicz, M	1
Reichart, M	1
Rosner, E	1
Sokolovski, M	1
Rechavi, G	1
Amariglio, N	1
Trakhtenbrot, L	1
Bonadonna, G	2
Bonfante, V	2
Strobel, ES	1
Bauchmüller, K	1
Schmitt-Gräff, A	1
Engelhardt, M	1
Morbidini-Gaffney, S	1
Alpert, TE	1
Hatoum, GF	1
Sagerman, RH	1
Broglia, C	1
Levis, A	1
La Sala, A	1
Valentino, F	1
Chisesi, T	1
Sacchi, S	1
Corbella, F	1
Cavanna, L	1
Pavone, V	1
Molica, S	1
Corazza, GR	1
Fermé, C	2
Divine, M	1
Sonet, A	1
Bouafia, F	1
Bastard-Stamatoullas, A	1
Bordessoule, D	1
Voillat, L	1
Reman, O	1
Blanc, M	1
Gisselbrecht, C	2
Foltz, LM	1
Song, KW	1
Dupouy, N	1
Monconduit, M	1
Bosq, J	2
Verschueren, TA	1
Pény, AM	1
Tomiŝiĉ, R	1
Baaijens, MH	1
Lugtenburg, P	1
Lievens, Y	1
de Jong, D	1
Capra, M	1
Hewitt, M	1
Radford, M	1
Hayward, J	1
Weston, CL	1
Machin, D	1
Tan, WY	1
Hu, DS	1
Zeng, FY	1
Song, QB	1
Hu, S	1
Wei, L	1
Zhou, LQ	1
Glanzmann, C	1
Stahel, R	1
Brusamolino, E	2
Lazzarino, M	2
Orlandi, E	2
Canevari, A	1
Morra, E	1
Castelli, G	1
Alessandrino, EP	1
Pagnucco, G	2
Astori, C	1
Livraghi, A	1
Zanini, M	1
Santoro, A	1
Soncini, F	1
Devizzi, L	1
Villani, F	1
Castellani, MR	1
Negretti, E	1
Zucali, R	1
Salvagno, L	1
Sorarù, M	1
Sotti, G	1
Aversa, S	1
Chiarion Sileni, V	1
Mazzarotto, R	1
Scarzello, G	1
Bianco, A	1
Pappagallo, GL	1
Fiorentino, MV	1
Bendandi, M	1
Zaccaria, A	1
Visani, G	1
Stefanati, V	1
Cantagalli, F	1
Mancino, A	1
Macchi, S	1
Simoncelli, F	1
Tura, S	1
Lichtman, SM	1
Brody, J	1
Kaplan, MH	1
Susin, M	1
Koduru, P	1
Goh, JC	1
Rysenga, E	1
Linden, MD	1
Carey, JL	1
Ross, CW	1
Schnitzer, B	1
Sawdyk, M	1
Maeda, K	1
Montillo, M	1
Scarpelli, M	1
Discepoli, G	1
Catarini, M	1
Rychlicki, F	1
Leoni, P	1
Robinson, BA	1
Colls, BM	1
Fitzharris, BM	1
Atkinson, CH	1
Dietrich, PY	1
Cosset, JM	1
Bodis, S	1
Hayat, M	1
Fisher, PM	1
Dodwell, DJ	1
Bridges, LR	1
Cartwright, SC	1
Stone, J	1
Cascinu, S	1
Fedeli, A	1
Catalano, G	1
Bergeron, C	1
Le Moine, P	1
Le Prise-Fleury, E	1
Jouan, H	1
Tass, P	1
Darcel, F	1
Chatel, M	1
Edan, C	1
Patte, C	1
Faivre, J	1
Jenkin, D	1
Greenberg, M	1
Fitzgerald, A	1
Izumi, T	1
Ohtsuki, T	1
Ohya, K	1
Ogawa, Y	1
Yoshida, M	1
Muroi, K	1
Imagawa, S	1
Hatake, K	1
Kuriki, K	1
Saito, K	1
Miura, Y	1
Burney, IA	1
Malik, IA	1
Salloum, E	1
Tallini, G	1
Levy, A	1
Cooper, DL	1
Swerdlow, AJ	2
Barber, JA	2
Horwich, A	2
Cunningham, D	2
Milan, S	1
Omar, RZ	1
Redei, I	1
Mangan, KF	1
Ming, PL	1
Mullaney, MT	1
Rao, PN	1
Goldberg, SL	1
Klumpp, TR	1
van den Berg, H	1
Zsiros, J	1
Behrendt, H	1
Schellong, G	1
Riepenhausen, M	1
Creutzig, U	1
Ritter, J	1
Harbott, J	1
Mann, G	1
Gadner, H	1
Tsodikov, A	1
Yakovlev, A	1
Ohno, T	1
Trenn, G	1
Wu, G	1
Abou-Elella, A	1
Reis, HE	1
Chan, WC	1
Andrieu, JM	1
Colonna, P	1
André, M	1
Blaise, D	1
Colombat, P	1
Fleury, J	1
Milpied, N	1
Cahn, JY	1
Pico, JL	1
Bastion, Y	1
Kuentz, M	1
Nedellec, G	1
Attal, M	1
Arranz, R	1
Gil-Fernández, JJ	1
Muñoz, E	1
Acevedo, A	1
Sobrino, MP	1
Fernández-Rañada, JM	1
Nyandoto, P	1
Muhonen, T	1
Joensuu, H	1
Anselmo, AP	1
Klersy, C	1
Santoro, M	1
Lunghi, F	1
Maurizi-Enrici, R	1
Baroni, CD	1
Mandelli, F	1
Bernasconi, C	1
Sieber, M	1
Rüffer, U	1
Schalk, KP	1
Schwieder, G	1
Wulf, G	1
Dölken, G	1
Worst, P	1
Koch, P	1
Schmitz, N	1
Bruntsch, U	1
Tirier, C	1
Müller, U	1
Perry, JR	1
Brown, MT	1
Gockerman, JP	1
Aisenberg, AC	1
Kaplan, SS	1
Rybka, WB	1
Blom, J	1
Shekhter-Levin, S	1
Harrison, CN	1
Gregory, W	1
Hudson, GV	1
Devereux, S	1
Goldstone, AH	1
Hancock, B	1
Winfield, D	1
MacMillan, AK	1
Hoskin, P	1
Newland, AC	1
Milligan, D	1
Linch, DC	2
Hamilton, VM	1
Norris, C	1
Bunin, N	1
Goldwein, JW	1
Bunin, GR	1
Lange, B	1
Meadows, AT	1
Garaventa, A	1
Haupt, R	1
Panarello, C	1
Dodero, P	1
Gambini, C	1
Gambaro, M	1
Schoemaker, MJ	1
Allerton, R	1
Lister, TA	3
Rohatiner, AZ	2
Vaughan Hudson, G	1
Williams, MV	1
Cellai, E	1
Magrini, SM	1
Masala, G	1
Alterini, R	1
Costantini, AS	1
Rigacci, L	1
Olmastroni, L	1
Papi, MG	1
Spediacci, MA	1
Innocenti, F	1
Bellesi, G	1
Ferrini, PR	1
Biti, G	1
Yokoo, H	1
Kamiya, M	1
Sasaki, A	1
Hirato, J	1
Nakazato, Y	1
Kurachi, H	1
Kirchner, EM	1
Ebsen, M	1
Kirchner, J	1
Theegarten, D	1
Voigtmann, R	1
Radford, JA	1
Ryder, WD	1
Deakin, DP	1
Barbui, T	1
Lucie, NP	1
Rossi, A	1
Dunlop, DJ	1
Cowan, RA	1
Wilkinson, PM	1
Gupta, RK	1
James, RD	1
Shamash, J	1
Chang, J	1
Crowther, D	1
Morales, MD	1
González, FA	1
Villegas, A	1
del Potro, E	1
Díaz Mediavilla, J	1
Martínez, R	1
Alvarez, A	1
Colomé, JA	1
Avilés, A	1
Díaz-Maqueo, JC	1
Ayala, JR	1
Cortés, HD	1
García, EL	1
Ganesan, TS	1
Oza, A	1
Perry, N	1
D'Ardenne, J	1
Arnott, S	1
Stansfeld, AG	1
Shand, WS	1
Wrigley, PF	1
Zulian, GB	1
Mermillod, B	1
Alberto, P	1
Hayani, A	1
Mahoney, DH	1
Taylor, LD	1
Bayens, YC	1
Wiggers, T	1
Vroom, TM	1
Van Geel, AN	1