procarbazine has been researched along with Cafe-au-Lait Spots with Pulmonic Stenosis in 3 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate tumor responses, event-free survival (EFS), overall survival (OS), and toxicity of chemotherapy, children with neurofibromatosis type 1 (NF1) and progressive low-grade glioma were enrolled into the Children's Oncology Group (COG) A9952 protocol and treated with carboplatin and vincristine (CV)." | 9.22 | Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children's Oncology Group. ( Ater, JL; Booth, TN; Freyer, DR; Mazewski, CM; Packer, RJ; Pollack, IF; Sposto, R; Vezina, G; Xia, C, 2016) |
| "To evaluate tumor responses, event-free survival (EFS), overall survival (OS), and toxicity of chemotherapy, children with neurofibromatosis type 1 (NF1) and progressive low-grade glioma were enrolled into the Children's Oncology Group (COG) A9952 protocol and treated with carboplatin and vincristine (CV)." | 5.22 | Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children's Oncology Group. ( Ater, JL; Booth, TN; Freyer, DR; Mazewski, CM; Packer, RJ; Pollack, IF; Sposto, R; Vezina, G; Xia, C, 2016) |
| "Patients with neurofibromatosis type 1 (NF1) often have gliomas as a complication, most of which are benign pilocytic astrocytomas which have arisen in optic pathways." | 1.31 | Neurofibromatosis type 1-associated unusual pleomorphic astrocytoma displaying continual malignant progression. ( Hirato, J; Kamiya, M; Kurachi, H; Nakazato, Y; Sasaki, A; Yokoo, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ater, JL | 1 |
| Xia, C | 1 |
| Mazewski, CM | 1 |
| Booth, TN | 1 |
| Freyer, DR | 1 |
| Packer, RJ | 1 |
| Sposto, R | 1 |
| Vezina, G | 1 |
| Pollack, IF | 1 |
| Nicolin, G | 1 |
| Parkin, P | 1 |
| Mabbott, D | 1 |
| Hargrave, D | 1 |
| Bartels, U | 1 |
| Tabori, U | 1 |
| Rutka, J | 1 |
| Buncic, JR | 1 |
| Bouffet, E | 1 |
| Yokoo, H | 1 |
| Kamiya, M | 1 |
| Sasaki, A | 1 |
| Hirato, J | 1 |
| Nakazato, Y | 1 |
| Kurachi, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)[NCT05555550] | Early Phase 1 | 30 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for procarbazine and Cafe-au-Lait Spots with Pulmonic Stenosis
| Article | Year |
|---|---|
Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Child, Preschoo | 2016 |
2 other studies available for procarbazine and Cafe-au-Lait Spots with Pulmonic Stenosis
| Article | Year |
|---|---|
Natural history and outcome of optic pathway gliomas in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chronic; Carboplatin; Chil | 2009 |
Neurofibromatosis type 1-associated unusual pleomorphic astrocytoma displaying continual malignant progression.
Topics: Adolescent; Antigens, Nuclear; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biomarke | 2001 |