procarbazine has been researched along with Breast Cancer in 35 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty patients with advanced breast cancer, randomised to receive CMF or weekly low dose Epirubicin, were evaluated by UICC criteria of response and WHO toxicity criteria, in addition to three QoL instruments: the 'Qualitator' daily diary card, 4 weekly Nottingham Health Profile (NHP) and Linear Analogue Self-Assessment (LASA)." | 9.07 | Combination or mild single agent chemotherapy for advanced breast cancer? CMF vs epirubicin measuring quality of life. ( Bates, T; Baum, M; Dobbs, HJ; Ebbs, SR; Fallowfield, LJ; Fraser, SC, 1993) |
| "Forty patients with advanced breast cancer, randomised to receive CMF or weekly low dose Epirubicin, were evaluated by UICC criteria of response and WHO toxicity criteria, in addition to three QoL instruments: the 'Qualitator' daily diary card, 4 weekly Nottingham Health Profile (NHP) and Linear Analogue Self-Assessment (LASA)." | 5.07 | Combination or mild single agent chemotherapy for advanced breast cancer? CMF vs epirubicin measuring quality of life. ( Bates, T; Baum, M; Dobbs, HJ; Ebbs, SR; Fallowfield, LJ; Fraser, SC, 1993) |
| "Breast cancer survivors, those treated with procarbazine or other alkylating agents and those with a higher age at diagnosis are at highest risk of diminished ovarian function." | 4.95 | Chemotherapy-related late adverse effects on ovarian function in female survivors of childhood and young adult cancer: A systematic review. ( Kaspers, GJ; Lambalk, CB; Overbeek, A; van den Berg, MH; van Dulmen-den Broeder, E; van Leeuwen, FE, 2017) |
| " After a median follow-up of more than 6 years following MOPP (mechlorethamine/vincristine/procarbazine/prednisone) chemotherapy with or without radiotherapy, 5% of patients with Hodgkin's disease developed second primaries, 60% of which were leukemias." | 4.78 | Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects. ( Petru, E; Schmähl, D, 1991) |
| "We discuss the characteristics of breast cancer that occurs after Hodgkin's lymphoma and also treatment options that could be implemented." | 2.44 | Breast cancer after treatment of Hodgkin's lymphoma: general review. ( Alm El-Din, MA; El-Badawy, SA; Taghian, AG, 2008) |
| "The most frequent pathologies were Hodgkin's lymphoma and breast cancer." | 1.62 | Evaluation of ovarian reserve before and after chemotherapy. ( Ayadi, M; Bahri, O; Berjeb, KK; Braham, M; Chakroun, N; Chtourou, S; Debbabi, L; Fadhlaoui, A; Hamdoun, M; Hannachi, H; Kacem, K; Zemni, Z; Zhioua, F, 2021) |
| "We observed a linear radiation dose-response curve with an adjusted excess odds ratio (EOR) of 6." | 1.46 | Breast Cancer Risk After Radiation Therapy for Hodgkin Lymphoma: Influence of Gonadal Hormone Exposure. ( Aleman, BMP; Broeks, A; De Bruin, ML; de Vathaire, F; Diallo, I; Fase, S; Hauptmann, M; Janus, CPM; Kesminiene, A; Kooijman, KR; Krol, ADG; Krul, IM; Lybeert, ML; Opstal-van Winden, AWJ; Russell, NS; Schaapveld, M; van der Maazen, RWM; van Eggermond, AM; van Leeuwen, FE; Zijlstra, JM, 2017) |
| "Patients who survive Hodgkin lymphoma (HL) are at increased risk of secondary neoplasms (SNs)." | 1.43 | Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases. ( Çavdar, A; Ceyhan, K; Deda, H; Gökçora, İH; Gözdaşoğlu, S; Işıkman, E; Pamir, A; Taçyıldız, N; Uluoğlu, Ö; Ünal, E; Yavuz, G, 2016) |
| "Ductal invasive carcinoma and ductal carcinoma in situ represented, respectively, 51 cases (71%) and 14 cases (19%)." | 1.38 | Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option. ( Belin, L; Bollet, MA; Campana, F; Decaudin, D; Fourquet, A; Haberer, S; Kirova, YM; Le Scodan, R; Moisson, P; Pierga, JY; Reyal, F; Savignoni, A; Stevens, D, 2012) |
| "A past history of treated Hodgkin disease is a factor of risk for breast cancer and suggests the need for annual mammography screening 10 years after the end of treatment." | 1.29 | [Breast cancer after treatment of Hodgkin's disease]. ( Blanchot, J; Dugast, J; Grall, JY; Le Prise, E; Levêque, J; Meunier, B; Poulain, P, 1995) |
| "Two patients developed breast cancer 14 and 8 years after treatment of Hodgkin's disease." | 1.29 | Breast cancer developing after therapy for Hodgkin's disease. ( Cascinu, S; Catalano, G; Fedeli, A, 1993) |
| "Neoadjuvant chemotherapy in Hodgkin's disease has improved survival time and tolerance to irradiation, allowing a lowering of the total doses used and the volumes irradiated." | 1.28 | [Radiotherapy with neoadjuvant chemotherapy]. ( Alapetite, C; Baillet, F; Dessard-Diana, B; Housset, M; Jacquillat, C; Michel-Langlet, P, 1989) |
| "Two patients developed breast cancer after treatment of Hodgkin's disease." | 1.27 | Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease. ( Anderson, T; Cox, JD; Gillin, M; Greenberg, M; Janjan, NA; Schewe, K; Wilson, JF, 1988) |
| "A case of recurrent Hodgkin's disease of the "sarcomatoid" or "syncytial variant" type was seen that occurred as an extension from the mediastinum to a previously uninvolved extranodal site (breast) and pericardium after treatment of classical nodular sclerosing Hodgkin's disease based in the lymph nodes." | 1.27 | Recurrent "syncytial variant" of Hodgkin's disease: an immunohistologic diagnosis. ( Blaustein, JC; Lewkow, L, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (60.00) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 3 (8.57) | 29.6817 |
| 2010's | 5 (14.29) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Berjeb, KK | 1 |
| Debbabi, L | 1 |
| Braham, M | 1 |
| Zemni, Z | 1 |
| Chtourou, S | 1 |
| Hannachi, H | 1 |
| Hamdoun, M | 1 |
| Ayadi, M | 1 |
| Kacem, K | 1 |
| Zhioua, F | 1 |
| Fadhlaoui, A | 1 |
| Bahri, O | 1 |
| Chakroun, N | 1 |
| Krul, IM | 1 |
| Opstal-van Winden, AWJ | 1 |
| Aleman, BMP | 1 |
| Janus, CPM | 1 |
| van Eggermond, AM | 1 |
| De Bruin, ML | 1 |
| Hauptmann, M | 1 |
| Krol, ADG | 1 |
| Schaapveld, M | 1 |
| Broeks, A | 1 |
| Kooijman, KR | 1 |
| Fase, S | 1 |
| Lybeert, ML | 1 |
| Zijlstra, JM | 1 |
| van der Maazen, RWM | 1 |
| Kesminiene, A | 1 |
| Diallo, I | 1 |
| de Vathaire, F | 1 |
| Russell, NS | 1 |
| van Leeuwen, FE | 2 |
| Gözdaşoğlu, S | 1 |
| Pamir, A | 1 |
| Ünal, E | 1 |
| Gökçora, İH | 1 |
| Uluoğlu, Ö | 1 |
| Ceyhan, K | 1 |
| Deda, H | 1 |
| Işıkman, E | 1 |
| Yavuz, G | 1 |
| Taçyıldız, N | 1 |
| Çavdar, A | 1 |
| Conway, JL | 1 |
| Connors, JM | 1 |
| Tyldesley, S | 1 |
| Savage, KJ | 1 |
| Campbell, BA | 1 |
| Zheng, YY | 1 |
| Hamm, J | 1 |
| Pickles, T | 1 |
| Overbeek, A | 1 |
| van den Berg, MH | 1 |
| Kaspers, GJ | 1 |
| Lambalk, CB | 1 |
| van Dulmen-den Broeder, E | 1 |
| Alm El-Din, MA | 1 |
| El-Badawy, SA | 1 |
| Taghian, AG | 1 |
| Haberer, S | 1 |
| Belin, L | 1 |
| Le Scodan, R | 1 |
| Kirova, YM | 1 |
| Savignoni, A | 1 |
| Stevens, D | 1 |
| Moisson, P | 1 |
| Decaudin, D | 1 |
| Pierga, JY | 1 |
| Reyal, F | 1 |
| Campana, F | 1 |
| Fourquet, A | 1 |
| Bollet, MA | 1 |
| Longo, DL | 1 |
| Neuwelt, EA | 1 |
| Hill, SA | 1 |
| Frenkel, EP | 1 |
| Moser, K | 1 |
| Pohl, A | 1 |
| Greig, NH | 1 |
| Senapati, N | 1 |
| Houchens, D | 1 |
| Ovejera, A | 1 |
| Beard, R | 1 |
| Nines, R | 1 |
| Levêque, J | 1 |
| Meunier, B | 1 |
| Poulain, P | 1 |
| Blanchot, J | 1 |
| Dugast, J | 1 |
| Le Prise, E | 1 |
| Grall, JY | 1 |
| Cascinu, S | 1 |
| Fedeli, A | 1 |
| Catalano, G | 1 |
| Fraser, SC | 1 |
| Dobbs, HJ | 1 |
| Ebbs, SR | 1 |
| Fallowfield, LJ | 1 |
| Bates, T | 1 |
| Baum, M | 1 |
| Kaba, SE | 1 |
| Kyritsis, AP | 1 |
| Hess, K | 1 |
| Yung, WK | 1 |
| Mercier, R | 1 |
| Dakhil, S | 1 |
| Jaeckle, KA | 1 |
| Levin, VA | 1 |
| Sauter, C | 1 |
| Mattern, J | 2 |
| Kaufmann, M | 2 |
| Hinderer, H | 1 |
| Wayss, K | 2 |
| Volm, M | 2 |
| DeVita, VT | 1 |
| Baumgartner, G | 1 |
| Petru, E | 1 |
| Schmähl, D | 1 |
| Lowenthal, RM | 1 |
| Jestrimski, KW | 1 |
| Baillet, F | 1 |
| Housset, M | 1 |
| Dessard-Diana, B | 1 |
| Jacquillat, C | 1 |
| Michel-Langlet, P | 1 |
| Alapetite, C | 1 |
| Wang, QL | 1 |
| Love, RR | 1 |
| Leventhal, H | 1 |
| Easterling, DV | 1 |
| Nerenz, DR | 1 |
| Janjan, NA | 1 |
| Wilson, JF | 1 |
| Gillin, M | 1 |
| Anderson, T | 1 |
| Greenberg, M | 1 |
| Schewe, K | 1 |
| Cox, JD | 1 |
| España, P | 1 |
| Bonilla, F | 1 |
| Yebra, M | 1 |
| Diego, J | 1 |
| Alvarez de Mon, M | 1 |
| Marazuela, M | 1 |
| Durántez, A | 1 |
| Blaustein, JC | 1 |
| Lewkow, L | 1 |
| Carpenter, JT | 1 |
| Raney, M | 1 |
| Logan, T | 1 |
| Lehnert, M | 1 |
| Biffl, G | 1 |
| Wascher, H | 1 |
| Jordis-Lohausen, K | 1 |
| Wählby, S | 1 |
| Wilmanns, W | 1 |
| Binsack, T | 1 |
| Sauer, H | 1 |
| Lemon, HM | 1 |
| Goldenson, Y | 1 |
| Lev, L | 1 |
| Robinson, E | 1 |
| Frei, E | 1 |
| Schütze, U | 1 |
| Goerttler, K | 1 |
| Tasca, C | 1 |
8 reviews available for procarbazine and Breast Cancer
| Article | Year |
|---|---|
Chemotherapy-related late adverse effects on ovarian function in female survivors of childhood and young adult cancer: A systematic review.
Topics: Age Factors; Amenorrhea; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Breast Neoplasms; | 2017 |
Breast cancer after treatment of Hodgkin's lymphoma: general review.
Topics: Adolescent; Adult; Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast N | 2008 |
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
Chemotherapy of brain metastases: current status.
Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Humans; Injections, S | 1984 |
Human models of human diseases; breast cancer and the lymphomas.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Drug Therapy, Combination; | 1979 |
Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hod | 1991 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast | 1986 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
2 trials available for procarbazine and Breast Cancer
| Article | Year |
|---|---|
Combination or mild single agent chemotherapy for advanced breast cancer? CMF vs epirubicin measuring quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ep | 1993 |
TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neop | 1997 |
25 other studies available for procarbazine and Breast Cancer
| Article | Year |
|---|---|
Evaluation of ovarian reserve before and after chemotherapy.
Topics: Adolescent; Adult; Anti-Mullerian Hormone; Antineoplastic Combined Chemotherapy Protocols; Bleomycin | 2021 |
Breast Cancer Risk After Radiation Therapy for Hodgkin Lymphoma: Influence of Gonadal Hormone Exposure.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Breast; Breast Neoplasms; Carcinoma | 2017 |
Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases.
Topics: Adenoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Du | 2016 |
Secondary Breast Cancer Risk by Radiation Volume in Women With Hodgkin Lymphoma.
Topics: Adolescent; Adult; Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 2017 |
Locoregional treatment for breast carcinoma after Hodgkin's lymphoma: the breast conservation option.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms | 2012 |
Radiation therapy in the treatment of Hodgkin's disease--do you see what I see?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Chemotherapy, Adjuvant; | 2003 |
Osmotic blood-brain barrier modification and combination chemotherapy: concurrent tumor regression in areas of barrier opening and progression in brain regions distant to barrier opening.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; B | 1984 |
Ultrasonic hyperthermia and drugs as therapy for human tumor xenografts.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Female; Hot Temp | 1982 |
[Breast cancer after treatment of Hodgkin's disease].
Topics: Adenocarcinoma; Adult; Aftercare; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 1995 |
Breast cancer developing after therapy for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intr | 1993 |
[Diagnostic problems due to alternative medicine].
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast N | 2000 |
Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Count; Cell Division; Culture Techniq | 1975 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
[Radiotherapy with neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorub | 1989 |
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neop | 1989 |
Side effects and emotional distress during cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Cyclophosphamide; Doxor | 1989 |
Mammary carcinoma developing after radiotherapy and chemotherapy for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Female; Hodgkin | 1988 |
[Second tumors in patients treated for Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modali | 1988 |
Recurrent "syncytial variant" of Hodgkin's disease: an immunohistologic diagnosis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hodgkin Disease; Hu | 1987 |
Phase II evaluation of procarbazine in metastatic breast cancer: a Southeastern Cancer Study Group Trial.
Topics: Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Gastrointestin | 1986 |
A preliminary analysis of combination therapy with vincristine, adriamycin, and prednimustine (VAP) in advanced breast cancer: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dac | 1986 |
[Cytostatic polychemotherapy in the aged].
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dac | 1985 |
Oestriol and prevention of breast cancer.
Topics: Adolescent; Adult; Animals; Benz(a)Anthracenes; Breast Neoplasms; Estriol; Female; Humans; Hydroxyla | 1973 |
Status and perspectives in chemotherapy of Hodgkin's disease.
Topics: Animals; Antineoplastic Agents; Benzoates; Breast Neoplasms; Burkitt Lymphoma; Cyclophosphamide; Cyt | 1973 |
[Sensitivity testing of malignant human tumors against cytostatic agents. II].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; DNA, Neoplasm; Female; Humans; | 1972 |