procarbazine has been researched along with Brain Diseases in 5 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide (TMZ) has established antineoplastic activity in the central nervous system in other disease states, with a favorable toxicity profile." | 1.51 | Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma. ( Brenner, A; Butler, MJ; Faivre, G; Le, I, 2019) |
| "The disease appeared to be a diffuse encephalopathy frequently affecting the higher cortical functions." | 1.27 | Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study. ( Chak, LY; Cox, RS; Kushlan, PD; Porzig, KJ; Sikic, BI; Wasserstein, P; Zatz, LM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faivre, G | 1 |
| Butler, MJ | 1 |
| Le, I | 1 |
| Brenner, A | 1 |
| Cairncross, G | 1 |
| Swinnen, L | 1 |
| Bayer, R | 1 |
| Rosenfeld, S | 1 |
| Salzman, D | 1 |
| Paleologos, N | 1 |
| Kaminer, L | 1 |
| Forsyth, P | 1 |
| Stewart, D | 1 |
| Peterson, K | 1 |
| Hu, W | 1 |
| Macdonald, D | 1 |
| Ramsay, D | 1 |
| Smith, A | 1 |
| Greco, FA | 1 |
| Kolins, J | 1 |
| Rajjoub, RK | 1 |
| Brereton, HD | 1 |
| Ghatak, NR | 1 |
| Sawyer, DR | 1 |
| Chak, LY | 1 |
| Zatz, LM | 1 |
| Wasserstein, P | 1 |
| Cox, RS | 1 |
| Kushlan, PD | 1 |
| Porzig, KJ | 1 |
| Sikic, BI | 1 |
5 other studies available for procarbazine and Brain Diseases
| Article | Year |
|---|---|
Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Disea | 2019 |
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta | 2000 |
Hodgkin's disease and granulomatous angiitis of the central nervous system.
Topics: Adult; Brain Diseases; Cerebral Cortex; Chickenpox; Dexamethasone; Herpesvirus 3, Human; Hodgkin Dis | 1976 |
A morphologic study of opportunistic cerebral toxoplasmosis.
Topics: Aged; Brain Diseases; Carmustine; Hodgkin Disease; Humans; Male; Prednisone; Procarbazine; Radionucl | 1978 |
Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Diseases; Brain Neoplasms; | 1986 |