Page last updated: 2024-11-03

procarbazine and Brain Diseases

procarbazine has been researched along with Brain Diseases in 5 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Temozolomide (TMZ) has established antineoplastic activity in the central nervous system in other disease states, with a favorable toxicity profile."1.51Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma. ( Brenner, A; Butler, MJ; Faivre, G; Le, I, 2019)
"The disease appeared to be a diffuse encephalopathy frequently affecting the higher cortical functions."1.27Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study. ( Chak, LY; Cox, RS; Kushlan, PD; Porzig, KJ; Sikic, BI; Wasserstein, P; Zatz, LM, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faivre, G1
Butler, MJ1
Le, I1
Brenner, A1
Cairncross, G1
Swinnen, L1
Bayer, R1
Rosenfeld, S1
Salzman, D1
Paleologos, N1
Kaminer, L1
Forsyth, P1
Stewart, D1
Peterson, K1
Hu, W1
Macdonald, D1
Ramsay, D1
Smith, A1
Greco, FA1
Kolins, J1
Rajjoub, RK1
Brereton, HD1
Ghatak, NR1
Sawyer, DR1
Chak, LY1
Zatz, LM1
Wasserstein, P1
Cox, RS1
Kushlan, PD1
Porzig, KJ1
Sikic, BI1

Other Studies

5 other studies available for procarbazine and Brain Diseases

ArticleYear
Temozolomide as a Single Agent Maintenance Therapy in Elderly Patients With Primary CNS Lymphoma.
    Clinical lymphoma, myeloma & leukemia, 2019, Volume: 19, Issue:10

    Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Disea

2019
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
    Neuro-oncology, 2000, Volume: 2, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta

2000
Hodgkin's disease and granulomatous angiitis of the central nervous system.
    Cancer, 1976, Volume: 38, Issue:5

    Topics: Adult; Brain Diseases; Cerebral Cortex; Chickenpox; Dexamethasone; Herpesvirus 3, Human; Hodgkin Dis

1976
A morphologic study of opportunistic cerebral toxoplasmosis.
    Acta neuropathologica, 1978, Jun-30, Volume: 42, Issue:3

    Topics: Aged; Brain Diseases; Carmustine; Hodgkin Disease; Humans; Male; Prednisone; Procarbazine; Radionucl

1978
Neurologic dysfunction in patients treated for small cell carcinoma of the lung: a clinical and radiological study.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Diseases; Brain Neoplasms;

1986