procarbazine has been researched along with Bone Cancer in 16 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fourteen consecutive melanoma patients with evaluable metastatic disease were treated with combination chemotherapy including procarbazine, vincristine and lomustine (POC)." | 7.67 | Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC). ( Ardizzoni, A; Grimaldi, A; Repetto, L; Rosso, R; Sertoli, MR, 1987) |
| "The effects of various regimens of melphalan combination chemotherapy were evaluated in 508 patients with multiple myeloma." | 5.04 | Remission maintenance therapy for multiple myeloma. ( , 1975) |
| "Fourteen consecutive melanoma patients with evaluable metastatic disease were treated with combination chemotherapy including procarbazine, vincristine and lomustine (POC)." | 3.67 | Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC). ( Ardizzoni, A; Grimaldi, A; Repetto, L; Rosso, R; Sertoli, MR, 1987) |
| "To assess the value in Ewing's sarcoma of a new multiagent therapy (vincristine, cyclophosphamide, Adriamycin, (doxorubicin) procarbazine), 30 children with a localized tumor (eight distal, nine proximal, 13 central lesions) treated at the Institut Gustave-Roussy between 1973 and 1976 (E3), were pair-matched by site of primary with 30 control patients treated without intensive chemotherapy between 1967 and 1972 (E1) at the same institution, both groups having the same local radiotherapy." | 2.65 | Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial. ( Blache, R; Henry-Amar, M; Patte, C; Sarrazin, D; Schweisguth, O; Zucker, JM, 1983) |
| "Differences between Hodgkin's lymphoma (HL) patients in China and Western countries are known to exist, but data on Chinese patients with HL are limited." | 1.38 | Clinical characteristics of the patients with Hodgkin's lymphoma involving extranodal sites. ( Huang, JJ; Jiang, WQ; Li, ZM; Xia, Y; Zhu, YJ, 2012) |
| "Bone and soft tissue sarcomas have rarely been observed after treatment of Hodgkin's disease, and only a few cases are described in the literature." | 1.27 | Bone and soft tissue sarcomas in the follow-up of Hodgkin's disease. ( Banfi, A; Zanini, M; Zucali, R, 1983) |
| "Two osteosarcomas, an Ewing sarcoma, and a bronchogenic carcinoma were also studied and grew similarly." | 1.26 | Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum. ( Floersheim, GL; Nassenstein, D; Torhorst, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, ZM | 1 |
| Zhu, YJ | 1 |
| Xia, Y | 1 |
| Huang, JJ | 1 |
| Jiang, WQ | 1 |
| Cakar, M | 1 |
| Aksoy, S | 1 |
| Kilickap, S | 1 |
| Harputluoglu, H | 1 |
| Erman, M | 1 |
| Strobel, ES | 1 |
| Bauchmüller, K | 1 |
| Schmitt-Gräff, A | 1 |
| Engelhardt, M | 1 |
| Mandal, S | 1 |
| Mandal, AK | 1 |
| Zanini, M | 1 |
| Zucali, R | 1 |
| Banfi, A | 1 |
| Zucker, JM | 1 |
| Henry-Amar, M | 1 |
| Sarrazin, D | 1 |
| Blache, R | 1 |
| Patte, C | 1 |
| Schweisguth, O | 1 |
| Floersheim, GL | 1 |
| Nassenstein, D | 1 |
| Torhorst, J | 1 |
| Fried, G | 1 |
| Ben Arieh, Y | 1 |
| Haim, N | 1 |
| Dale, J | 1 |
| Stein, M | 1 |
| Foa, J | 1 |
| Carcassonne, Y | 1 |
| Bitran, JD | 1 |
| Desser, RK | 1 |
| DeMeester, TR | 1 |
| Colman, M | 1 |
| Evans, R | 1 |
| Billings, A | 1 |
| Griem, M | 1 |
| Rubenstein, L | 1 |
| Shapiro, C | 1 |
| Golomb, HM | 1 |
| Le Mevel, BP | 1 |
| Hoerni, B | 1 |
| Durant, D | 1 |
| Kenesi, C | 1 |
| Salle, M | 1 |
| Trifaud, A | 1 |
| Liegey-Bagari, D | 1 |
| Bainvel, JV | 1 |
| Rogez, JM | 1 |
| Fumoleau, P | 1 |
| Mazabraud, A | 1 |
| Dumont, J | 1 |
| Tomend, B | 1 |
| Brossel, E | 1 |
| Garetta, M | 1 |
| Guerrin, D | 1 |
| Jasmin, C | 1 |
| Sancho-Garnier, H | 1 |
| Gimenez, M | 1 |
| Repetto, L | 1 |
| Grimaldi, A | 1 |
| Ardizzoni, A | 1 |
| Sertoli, MR | 1 |
| Rosso, R | 1 |
| Spivack, SD | 1 |
| Eagan, RT | 1 |
| Maurer, LH | 1 |
| Forcier, RJ | 1 |
| Tulloh, M | 1 |
| Devita, VT | 1 |
| Serpick, AA | 1 |
| Carbone, PP | 1 |
2 reviews available for procarbazine and Bone Cancer
| Article | Year |
|---|---|
[Treatment of Kahler's disease].
Topics: Bone Neoplasms; Carmustine; Cyclophosphamide; Drug Therapy, Combination; Humans; Melphalan; Multiple | 1976 |
Drugs 5 years later: procarbazine.
Topics: Animals; Bone Neoplasms; Carcinogens; Carcinoma; Drug Evaluation; Hodgkin Disease; Humans; Lung Neop | 1974 |
2 trials available for procarbazine and Bone Cancer
| Article | Year |
|---|---|
Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neopl | 1983 |
Remission maintenance therapy for multiple myeloma.
Topics: Bone Neoplasms; Carmustine; Drug Therapy, Combination; Female; Humans; Male; Melphalan; Middle Aged; | 1975 |
12 other studies available for procarbazine and Bone Cancer
| Article | Year |
|---|---|
Clinical characteristics of the patients with Hodgkin's lymphoma involving extranodal sites.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; | 2012 |
Procarbazine, lomustine, vincristine combination may be effective in adult medulloblastoma patients with systemic metastases.
Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; | 2005 |
Occurrence of multiple myeloma 13 years after Hodgkin's disease: chance or consequence?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carmustine; Combined Modality | 2005 |
Malignant fibrous histiocytoma following radiation therapy and chemotherapy for Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Chemotherapy, Adju | 2007 |
Bone and soft tissue sarcomas in the follow-up of Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child, | 1983 |
Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Antilymphocyte Serum; Bone Neoplasms; Carcinoma; Child; | 1980 |
Primary Hodgkin's disease of the bone.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Doxorubicin; Femal | 1995 |
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; C | 1976 |
EORTC/GTO adjuvant chemotherapy program for primary Ewing's sarcoma: results at 5 years.
Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administrat | 1978 |
Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Female | 1987 |
Proceedings: Small cell carcinoma of the lung: staging, paraneoplastic syndromes, treatment, and survival.
Topics: Bone Marrow; Bone Neoplasms; Brain Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination | 1974 |
Combination chemotherapy in the treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Child; Cyclophosphamide; Drug Synerg | 1970 |