procarbazine has been researched along with Body Weight in 15 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pretreatment of rats for 6 weeks plus continued treatment during procarbazine administration with testosterone enanthate, 240 micrograms/100 g body weight, resulted in a marked protection of spermatogenesis." | 3.67 | Protection from procarbazine-induced damage of spermatogenesis in the rat by androgen. ( Bush, C; Delic, JI; Peckham, MJ, 1986) |
| "Because several previous authors have repeatedly described treatment with thiamine as one of the sufficient prophylactic measures in slowing the development of viscerocranial malformations, especially cleft alveolus and palate, it is of utmost importance that the timing of treatment and dosage of thiamine be taken into consideration not only in animal experiments but also when applying results to humans." | 1.30 | Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats. ( Bienengräber, V; Fanghänel, J; Kundt, G; Malek, FA, 1997) |
| "Procarbazine was administered intraperitoneally to Sprague-Dawley rats aged 14, 24, and 60 days in 3 weekly injections of 200 mg/kg." | 1.27 | Effect of sexual maturity on testicular injury subsequent to procarbazine administration in rats. ( Giglio, W; Huang, HF; Lee, Y; Pogach, LM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Serrou, B | 1 |
| Cupissol, D | 1 |
| Plagne, R | 1 |
| Boutin, P | 1 |
| Carcassone, Y | 1 |
| Michel, FB | 1 |
| Valdivieso, M | 2 |
| Bodey, GP | 2 |
| Benjamin, RS | 2 |
| Barkley, HT | 2 |
| Freeman, MB | 1 |
| Ertel, M | 1 |
| Smith, TL | 1 |
| Mountain, CF | 1 |
| Meistrich, ML | 1 |
| Wilson, G | 1 |
| Ye, WS | 1 |
| Kurdoglu, B | 1 |
| Parchuri, N | 1 |
| Terry, NH | 1 |
| Bienengräber, V | 1 |
| Fanghänel, J | 1 |
| Malek, FA | 1 |
| Kundt, G | 1 |
| Crawford, BA | 1 |
| Spaliviero, JA | 1 |
| Simpson, JM | 1 |
| Handelsman, DJ | 1 |
| Avilés, A | 2 |
| Neri, N | 1 |
| Díaz-Maqueo, JC | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| García, EL | 1 |
| Ward, JA | 1 |
| Robinson, J | 1 |
| Morris, ID | 1 |
| Druker, BJ | 1 |
| Rosenthal, DS | 1 |
| Canellos, GP | 1 |
| Frankmann, C | 1 |
| Murphy, WK | 1 |
| McMurtrey, MJ | 1 |
| Jeffries, DG | 1 |
| Welch, SR | 1 |
| Delic, JI | 1 |
| Bush, C | 1 |
| Peckham, MJ | 1 |
| Pogach, LM | 1 |
| Lee, Y | 1 |
| Giglio, W | 1 |
| Huang, HF | 1 |
| Finkelstein, DM | 1 |
| Ettinger, DS | 1 |
| Ruckdeschel, JC | 1 |
| Johnson, JM | 1 |
| Thompson, DJ | 1 |
| Haggerty, GC | 1 |
| Dyke, IL | 1 |
| Lower, CE | 1 |
| Floersheim, GL | 1 |
| Brune, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for procarbazine and Body Weight
| Article | Year |
|---|---|
Parenteral intravenous nutrition (PIVN) as an adjunct to chemotherapy in small cell anaplastic lung carcinoma.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bone Marr | 1981 |
Role of intravenous hyperalimentation as an adjunct to intensive chemotherapy for small cell bronchogenic carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bon | 1981 |
13 other studies available for procarbazine and Body Weight
| Article | Year |
|---|---|
Hormonal protection from procarbazine-induced testicular damage is selective for survival and recovery of stem spermatogonia.
Topics: Animals; Body Weight; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Gonadal Steroid Hormone | 1994 |
Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats.
Topics: Abnormalities, Drug-Induced; Alveolar Process; Animals; Body Weight; Bone and Bones; Cleft Palate; C | 1997 |
Testing the gonadal regression-cytoprotection hypothesis.
Topics: Animals; Antineoplastic Agents; Body Weight; Doxorubicin; Genotype; Gonadotropins; Male; Mice; Organ | 1998 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
Strain-dependency of procarbazine-induced testicular toxicity.
Topics: Animals; Body Weight; Chorionic Gonadotropin; Genitalia, Male; Iodine Radioisotopes; Male; Organ Siz | 1989 |
Chlorambucil, vinblastine, procarbazine, and prednisone. An effective but less toxic regimen than MOPP for advanced-stage Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chlorambucil; Female; Hodg | 1989 |
Long-term effects of intravenous hyperalimentation administered during intensive chemotherapy for small cell bronchogenic carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcino | 1987 |
Protection from procarbazine-induced damage of spermatogenesis in the rat by androgen.
Topics: Androgens; Animals; Body Weight; Follicle Stimulating Hormone; Genitalia, Male; Luteinizing Hormone; | 1986 |
Effect of sexual maturity on testicular injury subsequent to procarbazine administration in rats.
Topics: Animals; Body Weight; Hormones; Leydig Cells; Male; Metals; Organ Size; Procarbazine; Radioimmunoass | 1988 |
Long-term survivors in metastatic non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study.
Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Body Wei | 1986 |
The effect of prenatal procarbazine treatment on brain development in the rat.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Dose-Response Relationship, Drug; Female; Mate | 1985 |
The haematological response to the immunosuppressive methylhydrazine derivates procarbazine and Ro 4-6824.
Topics: Animals; Antilymphocyte Serum; Antineoplastic Agents; Benzoates; Blood Platelets; Body Weight; Eryth | 1971 |