procarbazine has been researched along with Blast Crisis in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Blast Crisis: An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 74% of the acute myeloid leukemia patients, the truncated inhibitor was detected." | 1.29 | Urinary excretion of proteolyzed alpha1-antitrypsin: specificity, quantitation, and relation to therapy response in patients with acute myeloid leukemia. ( Busch, R; Dengler, R; Eger, G; Emmerich, B; Münstermann, U; Plewan, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dengler, R | 1 |
| Plewan, A | 1 |
| Münstermann, U | 1 |
| Busch, R | 1 |
| Eger, G | 1 |
| Emmerich, B | 1 |
| Kaplan, SS | 1 |
| Rybka, WB | 1 |
| Blom, J | 1 |
| Shekhter-Levin, S | 1 |
2 other studies available for procarbazine and Blast Crisis
| Article | Year |
|---|---|
Urinary excretion of proteolyzed alpha1-antitrypsin: specificity, quantitation, and relation to therapy response in patients with acute myeloid leukemia.
Topics: Adult; Aged; alpha 1-Antitrypsin; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; | 1995 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberra | 1998 |