procarbazine has been researched along with Benign Cerebellar Neoplasms in 19 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized postoperative trial, adjuvant post-irradiation chemotherapy, consisting of nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP), was tested versus radiation therapy alone for newly diagnosed medulloblastoma in patients between 1 and 21 years of age." | 9.07 | Nitrogen mustard, vincristine, procarbazine, and prednisone as adjuvant chemotherapy in the treatment of medulloblastoma. A Pediatric Oncology Group study. ( Boyett, JM; Camitta, B; Cornell, CJ; Kim, TH; Krischer, JP; Kun, L; Laurent, JP; Link, M; Luthy, AR; Ragab, AH, 1991) |
| "Forty-seven patients with medulloblastoma were treated postoperatively with procarbazine, followed by craniospinal radiation therapy in combination with hydroxyurea." | 7.67 | Treatment of medulloblastoma with procarbazine, hydroxyurea, and reduced radiation doses to whole brain and spine. ( Davis, RL; Edwards, MS; Fulton, D; Levin, VA; Liu, HC; Rodriguez, LA; Silver, P; Wara, W; Wilson, CB, 1988) |
| "The survival of 20 children with medulloblastoma who received adjuvant chemotherapy with procarbazine, vincristine and prednisone after resection and craniospinal irradiation is compared with the preliminary results of the Children's Cancer Study Group (CCSG) and the international Society of Pediatric Oncology (SIOP) medulloblastoma studies." | 7.66 | Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report. ( Berchtold, W; Bernasconi, S; Feldges, A; Imbach, P; Lüthi, A; Plüss, HJ; Seiler, RW; Vassella, F; Wagner, HP; Wyss, M, 1981) |
| "In a randomized postoperative trial, adjuvant post-irradiation chemotherapy, consisting of nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP), was tested versus radiation therapy alone for newly diagnosed medulloblastoma in patients between 1 and 21 years of age." | 5.07 | Nitrogen mustard, vincristine, procarbazine, and prednisone as adjuvant chemotherapy in the treatment of medulloblastoma. A Pediatric Oncology Group study. ( Boyett, JM; Camitta, B; Cornell, CJ; Kim, TH; Krischer, JP; Kun, L; Laurent, JP; Link, M; Luthy, AR; Ragab, AH, 1991) |
| "Within 3 weeks of definitive surgery, 571 adult patients with histologically confirmed, supratentorial malignant gliomas were randomly assigned to receive one of three chemotherapy regimens: BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) alone, alternating courses (every 8 weeks) of BCNU and procarbazine, or BCNU plus hydroxyurea alternating with procarbazine plus VM-26 (epipodophyllotoxin)." | 5.06 | Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001. ( Burger, PC; Green, SB; Mahaley, MS; Mealey, J; Ransohoff, J; Robertson, JT; Selker, RG; Shapiro, WR; Strike, TA; VanGilder, JC, 1989) |
| " The drug combination vincristine, procarbazine, and dibromdulcitol proved to be effective in a pilot trial on relapsed medulloblastomas: 8 complete and 4 partial remissions were achieved from 16 cases." | 3.68 | Treatment of malignant scala posterior brain tumors in children: the chemotherapy of relapsed medulloblastoma with a dibromdulcitol containing drug regime and pharmacokinetic studies of dibromdulcitol in children. ( Kálmánchey, R; Koóos, R; Paraicz, E; Schuler, D; Somló, P, 1992) |
| "Forty-seven patients with medulloblastoma were treated postoperatively with procarbazine, followed by craniospinal radiation therapy in combination with hydroxyurea." | 3.67 | Treatment of medulloblastoma with procarbazine, hydroxyurea, and reduced radiation doses to whole brain and spine. ( Davis, RL; Edwards, MS; Fulton, D; Levin, VA; Liu, HC; Rodriguez, LA; Silver, P; Wara, W; Wilson, CB, 1988) |
| "The survival of 20 children with medulloblastoma who received adjuvant chemotherapy with procarbazine, vincristine and prednisone after resection and craniospinal irradiation is compared with the preliminary results of the Children's Cancer Study Group (CCSG) and the international Society of Pediatric Oncology (SIOP) medulloblastoma studies." | 3.66 | Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report. ( Berchtold, W; Bernasconi, S; Feldges, A; Imbach, P; Lüthi, A; Plüss, HJ; Seiler, RW; Vassella, F; Wagner, HP; Wyss, M, 1981) |
| "Medulloblastoma is a rare tumor in adult." | 2.39 | High dose chemotherapy with stem-cell transplantation in a metastatic medulloblastoma in an adult: a case report and review of the literature. ( Cottu, PH; Epardeau, B; Espie, M; Extra, JM; Giacchetti, S; Marty, M; Mignot, L; Visot, B, 1994) |
| "Infants and young children who have brain tumors have a poor rate of survival and high treatment associated morbidity." | 1.30 | MOPP chemotherapy without irradiation as primary postsurgical therapy for brain tumors in infants and young children. ( Ater, JL; Bruner, J; Copeland, DR; Moore, B; van Eys, J; Woo, SY, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vigneron, C | 1 |
| Antoni, D | 1 |
| Coca, A | 1 |
| Entz-Werlé, N | 1 |
| Lutz, P | 1 |
| Spiegel, A | 1 |
| Jannier, S | 1 |
| Niederst, C | 1 |
| Jarnet, D | 1 |
| Meyer, P | 1 |
| Kehrli, P | 1 |
| Noël, G | 1 |
| Hamasaki, K | 1 |
| Nakamura, H | 1 |
| Ueda, Y | 1 |
| Makino, K | 1 |
| Kuratsu, J | 1 |
| Brandes, AA | 1 |
| Ermani, M | 1 |
| Amista, P | 1 |
| Basso, U | 1 |
| Vastola, F | 1 |
| Gardiman, M | 1 |
| Iuzzolino, P | 1 |
| Turazzi, S | 1 |
| Rotilio, A | 1 |
| Volpin, L | 1 |
| Mazza, C | 1 |
| Sainati, L | 1 |
| Ammannati, F | 1 |
| Berti, F | 1 |
| Pezzotta, S | 1 |
| Knerich, R | 1 |
| Butti, G | 1 |
| Seiler, RW | 1 |
| Bernasconi, S | 1 |
| Berchtold, W | 1 |
| Feldges, A | 1 |
| Imbach, P | 1 |
| Lüthi, A | 1 |
| Plüss, HJ | 1 |
| Vassella, F | 1 |
| Wyss, M | 1 |
| Wagner, HP | 1 |
| Cottu, PH | 1 |
| Giacchetti, S | 1 |
| Mignot, L | 1 |
| Epardeau, B | 1 |
| Visot, B | 1 |
| Extra, JM | 1 |
| Espie, M | 1 |
| Marty, M | 1 |
| Grabenbauer, GG | 1 |
| Löhnert, C | 1 |
| Erhardt, J | 1 |
| Buchfelder, M | 1 |
| Neubauer, U | 1 |
| Beck, JD | 1 |
| Reitz, S | 1 |
| Seyer, H | 1 |
| Thierauf, P | 1 |
| Fietkau, R | 1 |
| Ater, JL | 1 |
| van Eys, J | 3 |
| Woo, SY | 1 |
| Moore, B | 1 |
| Copeland, DR | 1 |
| Bruner, J | 1 |
| Kochi, M | 1 |
| Ushio, Y | 1 |
| Boratyński, W | 1 |
| Schuler, D | 1 |
| Somló, P | 1 |
| Koóos, R | 1 |
| Kálmánchey, R | 1 |
| Paraicz, E | 1 |
| Krischer, JP | 1 |
| Ragab, AH | 1 |
| Kun, L | 1 |
| Kim, TH | 1 |
| Laurent, JP | 1 |
| Boyett, JM | 1 |
| Cornell, CJ | 1 |
| Link, M | 1 |
| Luthy, AR | 1 |
| Camitta, B | 1 |
| Kretschmar, CS | 2 |
| Tarbell, NJ | 2 |
| Kupsky, W | 1 |
| Lavally, BL | 2 |
| Loeffler, JS | 2 |
| Wolfe, L | 1 |
| Strand, R | 1 |
| Scott, RM | 1 |
| Sallan, SE | 2 |
| Shapiro, WR | 1 |
| Green, SB | 1 |
| Burger, PC | 1 |
| Mahaley, MS | 1 |
| Selker, RG | 1 |
| VanGilder, JC | 1 |
| Robertson, JT | 1 |
| Ransohoff, J | 1 |
| Mealey, J | 1 |
| Strike, TA | 1 |
| Levin, VA | 1 |
| Rodriguez, LA | 1 |
| Edwards, MS | 1 |
| Wara, W | 1 |
| Liu, HC | 1 |
| Fulton, D | 1 |
| Davis, RL | 1 |
| Wilson, CB | 1 |
| Silver, P | 1 |
| Winston, KR | 1 |
| Fischer, EG | 1 |
| Chastagner, P | 1 |
| Olive, D | 1 |
| Philip, T | 1 |
| Zucker, JM | 1 |
| Czorny, A | 1 |
| Lapras, C | 1 |
| Brunat-Mentigny, M | 1 |
| Baram, TZ | 1 |
| Dowell, RE | 1 |
| Cangir, A | 2 |
| Pack, B | 1 |
| Bruner, JM | 1 |
| Coody, D | 1 |
| Smith, B | 1 |
2 reviews available for procarbazine and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
High dose chemotherapy with stem-cell transplantation in a metastatic medulloblastoma in an adult: a case report and review of the literature.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant | 1994 |
[Chemo-radiotherapy for malignant brain tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Central Nervous System | 2002 |
3 trials available for procarbazine and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
Chemotherapy for medulloblastoma in children. Current status and future prospects.
Topics: Adolescent; Cerebellar Neoplasms; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, C | 1982 |
Nitrogen mustard, vincristine, procarbazine, and prednisone as adjuvant chemotherapy in the treatment of medulloblastoma. A Pediatric Oncology Group study.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms | 1991 |
Randomized trial of three chemotherapy regimens and two radiotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cerebellar Neoplasms; Clinical Trials as | 1989 |
14 other studies available for procarbazine and Benign Cerebellar Neoplasms
| Article | Year |
|---|---|
[Pediatric medulloblastoma: Retrospective series of 52 patients].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherapy, Adju | 2016 |
Radiation-induced glioblastoma occurring 35 years after radiation therapy for medulloblastoma: case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Glioblastoma; Humans; M | 2010 |
The treatment of adults with medulloblastoma: a prospective study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Disease-Free Survival; | 2003 |
Adjuvant chemotherapy with procarbazine, vincristine and prednisone for medulloblastomas. A preliminary report.
Topics: Cerebellar Neoplasms; Child; Drug Therapy, Combination; Humans; Lomustine; Medulloblastoma; Postoper | 1981 |
[Medulloblastomas--the results after postoperative radiotherapy with and without adjuvant chemotherapy].
Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Ne | 1993 |
MOPP chemotherapy without irradiation as primary postsurgical therapy for brain tumors in infants and young children.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebellar Neoplasms; Chemotherapy, | 1997 |
[Results of combined treatment of neoplasms of the posterior cranial fossa in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Cerebellar Neoplasms; Child | 1992 |
Treatment of malignant scala posterior brain tumors in children: the chemotherapy of relapsed medulloblastoma with a dibromdulcitol containing drug regime and pharmacokinetic studies of dibromdulcitol in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1992 |
Pre-irradiation chemotherapy for infants and children with medulloblastoma: a preliminary report.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1989 |
Treatment of medulloblastoma with procarbazine, hydroxyurea, and reduced radiation doses to whole brain and spine.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain; Cerebellar Neoplasms; Child; Comb | 1988 |
Pre-radiation chemotherapy for infants and poor prognosis children with medulloblastoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Child, Pres | 1988 |
[Efficacy of the "8 drugs in a day" protocol in brain tumors in children].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cer | 1988 |
Survival and neurologic outcome of infants with medulloblastoma treated with surgery and MOPP chemotherapy. A preliminary report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child, Preschool; Combined Mod | 1987 |
MOPP regimen as primary chemotherapy for brain tumors in infants.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; | 1985 |