procarbazine has been researched along with Bacterial Disease in 4 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc." | 1.25 | [Side effects in immunosuppressive therapy]. ( Thumb, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valdivieso, M | 1 |
| Cabanillas, F | 1 |
| Keating, M | 1 |
| Barkley, HT | 1 |
| Murphy, WK | 1 |
| Burgess, MA | 1 |
| Frazier, H | 1 |
| Chen, T | 1 |
| Bodey, GP | 1 |
| Gerhartz, HH | 1 |
| Engelhard, M | 1 |
| Meusers, P | 1 |
| Brittinger, G | 1 |
| Wilmanns, W | 1 |
| Schlimok, G | 1 |
| Mueller, P | 1 |
| Huhn, D | 1 |
| Musch, R | 1 |
| Siegert, W | 1 |
| Thumb, N | 1 |
| Anderson, T | 1 |
| Schein, PS | 1 |
| Jencks, JA | 1 |
| Binder, RA | 1 |
1 trial available for procarbazine and Bacterial Disease
| Article | Year |
|---|---|
Randomized, double-blind, placebo-controlled, phase III study of recombinant human granulocyte-macrophage colony-stimulating factor as adjunct to induction treatment of high-grade malignant non-Hodgkin's lymphomas.
Topics: Adolescent; Adult; Aged; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infec | 1993 |
3 other studies available for procarbazine and Bacterial Disease
| Article | Year |
|---|---|
Effects of intensive induction chemotherapy for extensive-disease small cell bronchogenic carcinoma in protected environment-prophylactic antibiotic units.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carcinoma, Bronch | 1984 |
[Side effects in immunosuppressive therapy].
Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu | 1975 |
The nitroblue tetrazolium (NBT) dye test in determining fever source in lymphoma.
Topics: Bacterial Infections; Diagnosis, Differential; Evaluation Studies as Topic; False Positive Reactions | 1974 |