procarbazine has been researched along with Azoospermia in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Azoospermia: A condition of having no sperm present in the ejaculate (SEMEN).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azoospermia was observed in 90% of patients treated with chemotherapy alone, 67% of those treated with combined modality and 11% of those treated with radiotherapy alone (P < 0." | 1.35 | Assessment of male fertility in patients with Hodgkin's lymphoma treated in the German Hodgkin Study Group (GHSG) clinical trials. ( Behringer, K; Diehl, V; Engert, A; Fuchs, M; Halbsguth, T; Josting, A; Nogova, L; Reineke, T; Sieniawski, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sieniawski, M | 2 |
| Reineke, T | 2 |
| Josting, A | 2 |
| Nogova, L | 2 |
| Behringer, K | 1 |
| Halbsguth, T | 1 |
| Fuchs, M | 1 |
| Diehl, V | 2 |
| Engert, A | 2 |
| Pfistner, B | 1 |
1 trial available for procarbazine and Azoospermia
| Article | Year |
|---|---|
Fertility in male patients with advanced Hodgkin lymphoma treated with BEACOPP: a report of the German Hodgkin Study Group (GHSG).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azoospermia; Bleomycin; Cyclophos | 2008 |
1 other study available for procarbazine and Azoospermia
| Article | Year |
|---|---|
Assessment of male fertility in patients with Hodgkin's lymphoma treated in the German Hodgkin Study Group (GHSG) clinical trials.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azoospermia; Bleomycin; Combined | 2008 |