Page last updated: 2024-11-03

procarbazine and Astroblastoma

procarbazine has been researched along with Astroblastoma in 9 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
"Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity."2.71Initial chemotherapy in gliomatosis cerebri. ( Carpentier, A; Cartalat-Carel, S; Chinot, O; Cougnard, J; Delattre, JY; Djafari, L; Duffau, H; Gervais, H; Hoang-Xuan, K; Honnorat, J; Laigle, F; Mokhtari, K; Napolitano, M; Sanson, M; Taillandier, L; Taillibert, S, 2004)
"The diagnosis of gliomatosis cerebri with MR imaging remains difficult."2.42[Gliomatosis cerebri: report of 3 cases and review of recent literatures]. ( Arai, M; Kaizaki, Y; Kashihara, K; Kitamura, Y; Taguchi, M, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (77.78)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glas, M2
Rasch, K2
Wiewrodt, D2
Weller, M2
Herrlinger, U2
Kong, DS1
Kim, ST1
Lee, JI1
Suh, YL1
Lim, DH1
Kim, WS1
Kwon, KH1
Park, K1
Kim, JH1
Nam, DH1
Bähr, O1
Felsberg, J1
Schabet, M1
Simon, M1
Urbach, H1
Steinbach, JP1
Rieger, J1
Fimmers, R1
Bamberg, M1
Nägele, T1
Reifenberger, G1
Louis, E1
Keime-Guibert, F1
Delattre, JY2
Sanson, M2
Schiff, D1
Arai, M1
Kashihara, K1
Kaizaki, Y1
Taguchi, M1
Kitamura, Y1
Chamberlain, MC1
Cartalat-Carel, S1
Taillibert, S1
Napolitano, M1
Djafari, L1
Cougnard, J1
Gervais, H1
Laigle, F1
Carpentier, A1
Mokhtari, K1
Taillandier, L1
Chinot, O1
Duffau, H1
Honnorat, J1
Hoang-Xuan, K1
Piccirilli, M1
Landi, A1
Salvati, M1

Reviews

1 review available for procarbazine and Astroblastoma

ArticleYear
[Gliomatosis cerebri: report of 3 cases and review of recent literatures].
    No to shinkei = Brain and nerve, 2003, Volume: 55, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Diagnosis, Diff

2003

Trials

3 trials available for procarbazine and Astroblastoma

ArticleYear
Impact of adjuvant chemotherapy for gliomatosis cerebri.
    BMC cancer, 2010, Aug-13, Volume: 10

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine

2010
NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri.
    Annals of neurology, 2011, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumo

2011
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004

Other Studies

5 other studies available for procarbazine and Astroblastoma

ArticleYear
Procarbazine and CCNU as initial treatment in gliomatosis cerebri.
    Oncology, 2008, Volume: 75, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease-Free Survival;

2008
Dramatic response to chemotherapy in oligodendroglial gliomatosis cerebri.
    Neurology, 2003, Jan-14, Volume: 60, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Corpus Callosum; Fro

2003
Dramatic response to chemotherapy in oligodendroglial gliomatosis cerebri.
    Neurology, 2003, Aug-12, Volume: 61, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair

2003
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006