procarbazine has been researched along with Anemia, Aplastic in 24 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a patient who developed aplastic anemia after three courses of cyclohexylchloroethylnitrousurea (CCNU), procarbazine and oncovine administered after craniotomy and irradiation for brain astrocytoma." | 3.69 | Aplastic anemia induced by cyclohexylchloroethylnitrousurea. ( Elis, A; Lishner, M; Ravid, M; Savin, H, 1994) |
| "Forty-nine patients with severe aplastic anemia, 33 due to unknown cause, 11 drug or chemical related, 2 associated with hepatitis, 1 with paroxysmal nocturnal hemoglobinuria, and 2 possibly associated with Fanconi syndrome did not show recovery after 0." | 2.64 | Aplastic anemia treated by allogeneic bone marrow transplantation: a report on 49 new cases from Seattle. ( Buckner, CD; Clift, RA; Fefer, A; Fernando, LP; Giblett, ER; Goodell, BW; Johnson, FL; Lerner, KG; Neiman, PE; Sanders, JE; Storb, R; Thomas, ED; Weiden, PL, 1976) |
| "Fourteen patients with aplastic anemia and one with the Wiskott-Aldrich syndrome who were specifically sensitized against their donors were successfully engrafted with bone marrow from those donors." | 1.26 | Successful bone marrow transplantation in sensitized recipients. ( Levey, RH; Nathan, DG; Parkman, R; Rappeport, J; Rosen, F, 1979) |
| "A 26-year-old man with severe aplastic anemia was treated with high-dose Cyclophosphamide followed by the infusion of bone marrow cells from his HLA-identical sister." | 1.26 | Successful allogeneic bone marrow retransplantation with the same donor after graft rejection: application of a modified conditioning regimen. ( Frick, PG; Gmür, J; von Felten, A, 1979) |
| "Two cases of multitransfused severe aplastic anemia were retransplanted with bone marrow from the same HLA compatible sibling donors after subtotal body irradiation (800 r)." | 1.26 | Subtotal body irradiation with linear accelerator as preparation for marrow engraftment in aplastic anemia. ( Ernst, P; Walbom-Jørgensen, S, 1979) |
| "Nine patients with aplastic anemia rejected their first graft." | 1.26 | Experience with second marrow transplants. ( Buckner, CD; Clift, RA; Fefer, A; Neiman, PE; Storb, R; Thomas, ED; Wright, SE, 1976) |
| "A 15-year-old boy with aplastic anemia was successfully retransplanted with matched sibling bone marrow after failure of a first transplant from the same donor." | 1.25 | Retransplantation of human bone marrow. Two immunosuppressive drug regimens. ( Hokeness, S; Johnson, FL; Kersey, J; Krivit, W; Nesbit, M; Roloff, J, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (87.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kochbati, L | 1 |
| Fdhila, F | 1 |
| Belaid, I | 1 |
| Rifi, H | 1 |
| Barsaoui, S | 1 |
| Ben Romdhane, N | 1 |
| Bel Hadj Ali, Z | 1 |
| Mezlini, A | 1 |
| Oubich, F | 1 |
| Maalej, M | 1 |
| Auerbach, AD | 1 |
| Adler, B | 1 |
| O'Reilly, RJ | 1 |
| Kirkpatrick, D | 1 |
| Chaganti, RS | 1 |
| Kueh, YK | 1 |
| Tan, YO | 1 |
| Sng, I | 1 |
| Rauff, A | 1 |
| Card, RT | 1 |
| Holmes, IH | 1 |
| Sugarman, RG | 1 |
| Storb, R | 6 |
| Thomas, ED | 6 |
| Gluckman, E | 1 |
| Devergie, A | 1 |
| Gerotta, I | 1 |
| Hors, J | 1 |
| Sasportes, M | 1 |
| Boiron, M | 1 |
| Bernard, J | 1 |
| Pflieger, H | 1 |
| Wiesneth, M | 1 |
| Arnold, R | 1 |
| Niethammer, D | 1 |
| Kleihauer, E | 1 |
| Kersey, JH | 1 |
| Kim, T | 1 |
| Levitt, S | 1 |
| Krivit, W | 2 |
| Nesbit, ME | 1 |
| Coccia, P | 1 |
| Warkentin, P | 1 |
| O'Leary, M | 1 |
| Ramsay, NK | 1 |
| Sullivan, KM | 1 |
| Shulman, HM | 1 |
| Shaw, CM | 1 |
| Spence, A | 1 |
| Beckham, C | 1 |
| Clift, RA | 5 |
| Buckner, CD | 5 |
| Stewart, P | 1 |
| Elis, A | 1 |
| Lishner, M | 1 |
| Savin, H | 1 |
| Ravid, M | 1 |
| Min, CK | 1 |
| Kim, DW | 1 |
| Lee, JW | 1 |
| Han, CW | 1 |
| Min, WS | 1 |
| Kim, CC | 1 |
| Weiden, PL | 3 |
| Fefer, A | 4 |
| Fernando, LP | 1 |
| Giblett, ER | 2 |
| Goodell, BW | 1 |
| Johnson, FL | 2 |
| Lerner, KG | 2 |
| Neiman, PE | 3 |
| Sanders, JE | 1 |
| Kersey, J | 1 |
| Roloff, J | 1 |
| Hokeness, S | 1 |
| Nesbit, M | 1 |
| Santos, GW | 1 |
| Elfenbein, GJ | 1 |
| Tutschka, PJ | 1 |
| Levey, RH | 2 |
| Parkman, R | 3 |
| Rappeport, J | 1 |
| Nathan, DG | 3 |
| Rosen, F | 1 |
| Gmür, J | 1 |
| Frick, PG | 1 |
| von Felten, A | 1 |
| Walbom-Jørgensen, S | 1 |
| Ernst, P | 1 |
| Longpre, B | 1 |
| Witherspoon, R | 1 |
| Wright, SE | 1 |
| Meuwissen, HJ | 1 |
| Moore, EC | 1 |
| Strauss, HS | 1 |
| Taft, E | 1 |
| Britten, A | 1 |
| Graham, TC | 1 |
| Camitta, BM | 1 |
| Rappeport, JM | 2 |
| Smith, BR | 1 |
| Guinan, EC | 1 |
| Ferrara, J | 1 |
| Viola, MV | 1 |
| Kovi, J | 1 |
| Nukhopadhyay, M | 1 |
| Düllmann, J | 1 |
| Wulfhekel, U | 1 |
| Drescher, S | 1 |
| Hausmann, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Different Doses of Anti-thymocyte Globin With 2.5 or 3.75mg/kg to Treat Child Severe Aplastic Anemia[NCT01997372] | Phase 4 | 100 participants (Anticipated) | Interventional | 2010-12-31 | Recruiting | ||
| A Single-Arm Phase 2 Study With Optimized Standard Protocol for Severe Aplastic Anemia[NCT02203396] | Phase 2 | 40 participants (Anticipated) | Interventional | 2014-08-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for procarbazine and Anemia, Aplastic
| Article | Year |
|---|---|
Bone marrow transplantation--present status.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; | 1979 |
Preceding transfusions and marrow graft rejection in dogs and man.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Transfusion; Bone Marrow Cells; Bone Marrow T | 1976 |
1 trial available for procarbazine and Anemia, Aplastic
| Article | Year |
|---|---|
Aplastic anemia treated by allogeneic bone marrow transplantation: a report on 49 new cases from Seattle.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; | 1976 |
21 other studies available for procarbazine and Anemia, Aplastic
| Article | Year |
|---|---|
[Pediatric Hodgkin disease in North Tunisia: clinical and therapeutic study].
Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiomyopa | 2012 |
Effect of procarbazine and cyclophosphamide on chromosome breakage in Fanconi anemia cells: relevance to bone marrow transplantation.
Topics: Anemia, Aplastic; Biotransformation; Bone Marrow Transplantation; Cells, Cultured; Child; Child, Pre | 1983 |
Reversal of red cell aplasia and marrow fibrosis in non-Hodgkin's lymphoma.
Topics: Adult; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Humans; L | 1983 |
Successful pregnancy after high dose chemotherapy and marrow transplantation for treatment of aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Transplantation; C | 1980 |
Bone marrow transplantation in 65 patients with severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child | 1981 |
Granulocyte transfusions in children.
Topics: Acute Disease; Agranulocytosis; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marr | 1981 |
Combined immunosuppression using cyclophosphamide plus total lymphoid irradiation in preparation for allogeneic marrow transplantation in humans.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Presc | 1980 |
Immediate and delayed neurotoxicity after mechlorethamine preparation for bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Central Nervous System; Central Ne | 1982 |
Aplastic anemia induced by cyclohexylchloroethylnitrousurea.
Topics: Adult; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Blood Cell Cou | 1994 |
Supplemental peripheral blood stem cells to decrease marrow rejection in adult patients with severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antigens, CD34; Antilymphocyte Serum; Bone Marrow Transplantati | 2002 |
Retransplantation of human bone marrow. Two immunosuppressive drug regimens.
Topics: Adolescent; Anemia, Aplastic; Animals; Antigen-Antibody Reactions; B-Lymphocytes; Bone Marrow Cells; | 1975 |
Successful bone marrow transplantation in sensitized recipients.
Topics: Anemia, Aplastic; Antibody-Dependent Cell Cytotoxicity; Antilymphocyte Serum; Bone Marrow; Bone Marr | 1979 |
Successful allogeneic bone marrow retransplantation with the same donor after graft rejection: application of a modified conditioning regimen.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide; Graft | 1979 |
Subtotal body irradiation with linear accelerator as preparation for marrow engraftment in aplastic anemia.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; Humans; Procarbazi | 1979 |
Recovery from aplastic anemia following attempted marrow transplantation.
Topics: Adult; Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rej | 1976 |
Experience with second marrow transplants.
Topics: Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; | 1976 |
Successful retransplantation of bone marrow following failure of initial engraftment in a patient with aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Transplantation; Child; Cyclo | 1976 |
Selection of patients for bone marrow transplantation in severe aplastic anemia.
Topics: Adolescent; Adult; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow | 1975 |
Selection of patients for bone marrow transplantation in severe aplastic anemia.
Topics: Adolescent; Adult; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow | 1975 |
Selection of patients for bone marrow transplantation in severe aplastic anemia.
Topics: Adolescent; Adult; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow | 1975 |
Selection of patients for bone marrow transplantation in severe aplastic anemia.
Topics: Adolescent; Adult; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow | 1975 |
Efficacy of a cyclophosphamide-procarbazine-antithymocyte serum regimen for prevention of graft rejection following bone marrow transplantation for transfused patients with aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marrow Transplantation; Cyclophospha | 1985 |
Reversal of myelofibrosis in Hodgkin disease.
Topics: Adult; Anemia, Aplastic; Biopsy, Needle; Cyclophosphamide; Female; Hodgkin Disease; Humans; Predniso | 1973 |
[Hairy cell leukaemia clinical, light- and electronmicroscopical findings (author's transl)].
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Anemia, Pernicious; Antibody Formation; Blood Platelets; C | 1974 |