procarbazine has been researched along with Anaphylaxis in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both anticancer chemotherapeutics and monoclonal antibodies have the potential for acute HSR." | 1.38 | Prevention and handling of acute allergic and infusion reactions in oncology. ( Joerger, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hutten, EM | 1 |
| Lambeck, AJA | 1 |
| Dijkstra, H | 1 |
| Nuver, J | 1 |
| Oude Elberink, HNG | 1 |
| Van de Ven, AAJM | 1 |
| Joerger, M | 1 |
2 other studies available for procarbazine and Anaphylaxis
| Article | Year |
|---|---|
Successful rapid desensitization in a glioma patient with procarbazine-mediated anaphylaxis.
Topics: Anaphylaxis; Basophils; Desensitization, Immunologic; Glioma; Humans; Procarbazine | 2021 |
Prevention and handling of acute allergic and infusion reactions in oncology.
Topics: Anaphylaxis; Antibodies, Monoclonal; Asparaginase; Drug Hypersensitivity; Humans; Immunoglobulin E; | 2012 |