Page last updated: 2024-11-03

procarbazine and Alopecia

procarbazine has been researched along with Alopecia in 12 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Alopecia: Absence of hair from areas where it is normally present.

Research Excerpts

ExcerptRelevanceReference
"A prospective phase II study of paclitaxel was performed in adult patients with recurrent hemispheric oligodendrogliomas."9.08Salvage chemotherapy with paclitaxel for recurrent oligodendrogliomas. ( Chamberlain, MC; Kormanik, PA, 1997)
"A prospective phase II study of paclitaxel was performed in adult patients with recurrent hemispheric oligodendrogliomas."5.08Salvage chemotherapy with paclitaxel for recurrent oligodendrogliomas. ( Chamberlain, MC; Kormanik, PA, 1997)
"Thirty-eight patients with advanced Hodgkin's disease were treated with a combination of cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP)."1.26Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP. ( Bloomfield, CD; Fortuny, I; Kennedy, BJ; Vosika, G; Weiss, RB, 1976)
"Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc."1.25[Side effects in immunosuppressive therapy]. ( Thumb, N, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Niu, Y1
Shi, YK1
He, XH1
Feng, FY1
Zhou, LQ1
Gu, DZ1
Bartels, H1
Schneider, B1
Feller, AC1
Kato, Y1
Takeda, H1
Mihara, H1
Kobayashi, H1
Kamijima, S1
Kuwahara, M1
Oguri, T1
Nagasaka, T1
Chamberlain, MC1
Kormanik, PA1
Lishner, M1
Manor, Y1
Kitay-Cohen, Y1
Avishay, AE1
Sutcliffe, SB1
Wrigley, PF1
Stansfeld, AG1
Malpas, JS1
Bloomfield, CD1
Weiss, RB1
Fortuny, I1
Vosika, G1
Kennedy, BJ1
Thumb, N1
Desser, RK1
Ultmann, JE1
Fairley, GH1
Freeman, JE1
Smith, KL1
Johnson, D1
Hustu, O1
Pratt, C1
Fleming, I1
Holton, C1
Cassady, JR1
Jaffe, N1

Reviews

1 review available for procarbazine and Alopecia

ArticleYear
The sensitivity of Hodgkin's disease to chemotherapeutic agents administered singly.
    Series haematologica (1968), 1973, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Alopecia; Antineoplastic Agents; Bleomycin; Blood Platelet Disorders; Carmu

1973

Trials

1 trial available for procarbazine and Alopecia

ArticleYear
Salvage chemotherapy with paclitaxel for recurrent oligodendrogliomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:12

    Topics: Adult; Alopecia; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols;

1997

Other Studies

10 other studies available for procarbazine and Alopecia

ArticleYear
[Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child;

2008
[Clinical aspects and therapy of anaplastic T-zone lymphoma].
    Deutsche medizinische Wochenschrift (1946), 1984, Jul-13, Volume: 109, Issue:28-29

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin;

1984
Oral low-dose etoposide therapy for refractory multiple myeloma with extramedullary involvement.
    Internal medicine (Tokyo, Japan), 1995, Volume: 34, Issue:10

    Topics: Administration, Oral; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; E

1995
Association between alopecia and response to aggressive chemotherapy in patients with Hodgkin's disease.
    Medical hypotheses, 1999, Volume: 53, Issue:5

    Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin

1999
Adriamycin, bleomycin, vinblastine and imidazole carboxamide (ABVD) therapy for advanced Hodgkin's disease resistant to mustine, vinblastine, procarbazine and prednisolone (MVPP).
    Cancer chemotherapy and pharmacology, 1979, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Alopecia; Antineoplastic Agents; Bleomycin; Child; Doxorubicin; Drug Administrati

1979
Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP.
    Cancer, 1976, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Alopecia; Antineoplastic Agents; Cyclophosphamide; Drug Therap

1976
[Side effects in immunosuppressive therapy].
    Acta medica Austriaca, 1975, Volume: 2, Issue:4

    Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu

1975
Blood and neoplastic diseases. Treatment of the lymphomas.
    British medical journal, 1974, Dec-28, Volume: 4, Issue:5947

    Topics: Alopecia; Bone Marrow; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Ne

1974
Concurrent chemotherapy and radiation therapy in the treatment of childhood and adolescent Hodgkin's disease.
    Cancer, 1974, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alopecia; Child; Child, Preschool; Cobalt Radioisotopes; Cyclophosph

1974
Protection from chemotherapeutic epilation by prior irradiation.
    Radiology, 1974, Volume: 112, Issue:1

    Topics: Adolescent; Alopecia; Antineoplastic Agents; Child; Cyclophosphamide; Drug Therapy, Combination; Fem

1974