procarbazine has been researched along with Agnogenic Myeloid Metaplasia in 7 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four patients with Hodgkin's disease and bone marrow fibrosis are presented in whom the clinical presentation was dominated by cytopenias; this was associated with a delayed diagnosis for an average of 20 months." | 1.28 | Hodgkin's disease presenting as myelofibrosis. ( Crawford, J; Kaufman, RE; Laszlo, J; Meadows, LM; Moore, JO; Rosse, WR, 1989) |
| "Malignant myelosclerosis or acute myelofibrosis is a rare acute myeloproliferative disorder characterized by pancytopenia, myeloblastosis and marrow fibrosis." | 1.26 | Malignant myelosclerosis (acute myelofibrosis): report of two cases following cytotoxic chemotherapy. ( Ali, NO; Janes, WO, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kueh, YK | 1 |
| Tan, YO | 1 |
| Sng, I | 1 |
| Rauff, A | 1 |
| Ali, NO | 1 |
| Janes, WO | 1 |
| Meadows, LM | 1 |
| Rosse, WR | 1 |
| Moore, JO | 1 |
| Crawford, J | 1 |
| Laszlo, J | 1 |
| Kaufman, RE | 1 |
| Carroll, WL | 1 |
| Berberich, FR | 1 |
| Glader, BE | 1 |
| Young, RC | 1 |
| Canellos, GP | 1 |
| Chabner, BA | 1 |
| Schein, PS | 1 |
| DeVita, VT | 1 |
| Pinedo, HM | 1 |
| Van Hemel, JO | 1 |
| Vrede, MA | 1 |
| Van der Sluys Veer, J | 1 |
| Viola, MV | 1 |
| Kovi, J | 1 |
| Nukhopadhyay, M | 1 |
1 trial available for procarbazine and Agnogenic Myeloid Metaplasia
| Article | Year |
|---|---|
Maintenance chemotherapy for advanced Hodgkin's disease in remission.
Topics: Blood Cell Count; Blood Platelets; Hodgkin Disease; Humans; Lymphocytes; Mechlorethamine; Nitrosoure | 1973 |
6 other studies available for procarbazine and Agnogenic Myeloid Metaplasia
| Article | Year |
|---|---|
Reversal of red cell aplasia and marrow fibrosis in non-Hodgkin's lymphoma.
Topics: Adult; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Humans; L | 1983 |
Malignant myelosclerosis (acute myelofibrosis): report of two cases following cytotoxic chemotherapy.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Glom | 1979 |
Hodgkin's disease presenting as myelofibrosis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Diagnosis, Differential; Female; | 1989 |
Pancytopenia with myelofibrosis. An unusual presentation of childhood Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Female; Hodgkin Disease; Humans; | 1986 |
Letter: Acute myelofibrosis and chromosome damage after procarbazine treatment.
Topics: Aged; Aging; Aneuploidy; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Humans; Male; Penil | 1974 |
Reversal of myelofibrosis in Hodgkin disease.
Topics: Adult; Anemia, Aplastic; Biopsy, Needle; Cyclophosphamide; Female; Hodgkin Disease; Humans; Predniso | 1973 |