procarbazine has been researched along with Aging in 3 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballova, V | 1 |
| Rüffer, JU | 1 |
| Haverkamp, H | 1 |
| Pfistner, B | 1 |
| Müller-Hermelink, HK | 1 |
| Dühmke, E | 1 |
| Worst, P | 1 |
| Wilhelmy, M | 1 |
| Naumann, R | 1 |
| Hentrich, M | 1 |
| Eich, HT | 1 |
| Josting, A | 1 |
| Löffler, M | 1 |
| Diehl, V | 1 |
| Engert, A | 1 |
| Johnson, JM | 1 |
| Thompson, DJ | 1 |
| Haggerty, GC | 1 |
| Dyke, IL | 1 |
| Lower, CE | 1 |
| Pinedo, HM | 1 |
| Van Hemel, JO | 1 |
| Vrede, MA | 1 |
| Van der Sluys Veer, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase Ib/II Trial of Combined SGN-35 (BrentuximabVedotin) Therapy With Cyclophosphamide, Procarbazine, Prednisone, Etoposide and Mitoxantrone (BrEPEM) for Older Patients With Untreated Hodgkin Lymphoma (HL)[NCT03576378] | Phase 1/Phase 2 | 41 participants (Actual) | Interventional | 2018-08-08 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for procarbazine and Aging
| Article | Year |
|---|---|
A prospectively randomized trial carried out by the German Hodgkin Study Group (GHSG) for elderly patients with advanced Hodgkin's disease comparing BEACOPP baseline and COPP-ABVD (study HD9elderly).
Topics: Administration, Oral; Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclop | 2005 |
2 other studies available for procarbazine and Aging
| Article | Year |
|---|---|
The effect of prenatal procarbazine treatment on brain development in the rat.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Dose-Response Relationship, Drug; Female; Mate | 1985 |
Letter: Acute myelofibrosis and chromosome damage after procarbazine treatment.
Topics: Aged; Aging; Aneuploidy; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Humans; Male; Penil | 1974 |