Page last updated: 2024-11-03

procarbazine and Adenoma

procarbazine has been researched along with Adenoma in 5 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" Hodgkin lymphoma survivors who were treated with infradiaphragmatic radiotherapy and/or high-dose procarbazine have an increased risk to develop colorectal cancer."5.24Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design. ( Aleman, BM; Bisseling, TM; Bleiker, EM; Carvalho, B; Cats, A; de Boer, JP; Janus, CP; Jóźwiak, K; Lansdorp-Vogelaar, I; Lugtenburg, PJ; Meijer, GA; Moons, LM; Petersen, EJ; Raemaekers, JM; Rigter, LS; Roesink, JM; Snaebjornsson, P; Spaander, MC; Te Riele, H; van der Maazen, RW; van Leerdam, ME; van Leeuwen, FE, 2017)
" We describe a 5-year-old boy with stage IV HD, successfully treated with MOPP (mechlorethamine, vincristine, procarbazine, and prednisone)/ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) chemotherapy followed by 35 Gy mantle radiotherapy who developed primary hyperparathyroidism because of benign PTA at the age of 20 years, and died of CS in thoracic vertebrae at the age of 22 years."3.76Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease. ( Albayrak, M; Coskun, U; Gursel, T; Kaya, Z; Keskin, EY; Kocak, U; Uluoglu, O, 2010)
" Tumours only appeared in those animals in which growth of the granuloma tissue was stimulated with a dose of croton oil."3.66Single dose carcinogenicity of procarbazine in rats. ( Maier, P; Zbinden, G, 1983)
"Patients who survive Hodgkin lymphoma (HL) are at increased risk of secondary neoplasms (SNs)."1.43Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases. ( Çavdar, A; Ceyhan, K; Deda, H; Gökçora, İH; Gözdaşoğlu, S; Işıkman, E; Pamir, A; Taçyıldız, N; Uluoğlu, Ö; Ünal, E; Yavuz, G, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gözdaşoğlu, S1
Pamir, A1
Ünal, E1
Gökçora, İH1
Uluoğlu, Ö2
Ceyhan, K1
Deda, H1
Işıkman, E1
Yavuz, G1
Taçyıldız, N1
Çavdar, A1
Rigter, LS1
Spaander, MC1
Moons, LM1
Bisseling, TM1
Aleman, BM1
de Boer, JP1
Lugtenburg, PJ1
Janus, CP1
Petersen, EJ1
Roesink, JM1
Raemaekers, JM1
van der Maazen, RW1
Cats, A1
Bleiker, EM1
Snaebjornsson, P1
Carvalho, B1
Lansdorp-Vogelaar, I1
Jóźwiak, K1
Te Riele, H1
Meijer, GA1
van Leeuwen, FE1
van Leerdam, ME1
Keskin, EY1
Gursel, T1
Albayrak, M1
Kaya, Z1
Coskun, U1
Kocak, U1
Zbinden, G1
Maier, P1
Draudin-Krylenko, VA1
Bukin, IuV1
Nikonova, TV1

Trials

1 trial available for procarbazine and Adenoma

ArticleYear
Colorectal cancer surveillance in Hodgkin lymphoma survivors at increased risk of therapy-related colorectal cancer: study design.
    BMC cancer, 2017, Feb-07, Volume: 17, Issue:1

    Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Protocols; Colonoscopy; Colo

2017

Other Studies

4 other studies available for procarbazine and Adenoma

ArticleYear
Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2016, Mar-05, Volume: 33, Issue:1

    Topics: Adenoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Du

2016
Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:7

    Topics: Adenoma; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child, Preschool; Chondrosarcoma

2010
Single dose carcinogenicity of procarbazine in rats.
    Cancer letters, 1983, Volume: 21, Issue:2

    Topics: Adenoma; Air; Animals; Carcinoma; Croton Oil; Fibrosarcoma; Granuloma; Injections, Intraperitoneal;

1983
[Anticarcinogenic action of vitamins PP and B6 in the natulan initiation of malignant growth in mice].
    Voprosy onkologii, 1989, Volume: 35, Issue:1

    Topics: Adenoma; Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Drug Interactions; Female; Lu

1989