procarbazine has been researched along with Acute Lymphoid Leukemia in 8 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We reviewed all reported cases of Burkitt's lymphoma and/or Burkitt's leukemia (BLL) occurring following therapy for Hodgkin's disease." | 2.39 | Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease. ( Cooper, DL; Levy, A; Salloum, E; Tallini, G, 1996) |
| "Concerning ANLL, the MOPP regimen was significantly associated with a higher risk: 3." | 1.31 | Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation. ( Andrieu, JM; Colonna, P; Delwail, V; Jais, JP, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kober, T | 1 |
| Hülsewede, H | 1 |
| Bohlius, J | 1 |
| Engert, A | 1 |
| Chamberlain, MC | 1 |
| Nishikawa, K | 1 |
| Salloum, E | 1 |
| Tallini, G | 1 |
| Levy, A | 1 |
| Cooper, DL | 1 |
| Soriano Guillén , L | 1 |
| Muñoz Calvo , MT | 1 |
| Pozo Román , J | 1 |
| Contra Gómez , T | 1 |
| Buño Soto , M | 1 |
| Argente Oliver , J | 1 |
| Chen, YC | 1 |
| Ho, CL | 1 |
| Kao, WY | 1 |
| Hwang, JM | 1 |
| Sheu, LF | 1 |
| Chao, TY | 1 |
| Delwail, V | 1 |
| Jais, JP | 1 |
| Colonna, P | 1 |
| Andrieu, JM | 1 |
| Swaffar, DS | 1 |
| Pomerantz, SC | 1 |
| Harker, WG | 1 |
| Yost, GS | 1 |
3 reviews available for procarbazine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Fourth biannual report of the Cochrane Haematological Malignancies Group.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2006 |
[Chemotherapy of relapsed AML and ALL].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Etoposide; Granulocyte Col | 1996 |
Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Cyclophosphamide | 1996 |
5 other studies available for procarbazine and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; C | 1994 |
[Changes in gonadal function in post-pubertal male survivors of acute lymphoblastic leukemia and Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Child; Cycl | 2000 |
Adult lymphoblastic lymphoma in Taiwan: an analysis of treatment results of 26 patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T | 2001 |
Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbaz | 2002 |
Non-enzymatic activation of procarbazine to active cytotoxic species.
Topics: Biotransformation; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cy | 1992 |