procaine has been researched along with Ventricular Fibrillation in 35 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery." | 6.68 | Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery. ( Berg, EM; Levang, OW; Sellevold, OF, 1995) |
| " Acute pretreatment with bretylium, 20 mg/kg intravenously, significantly increased the amount of infused ouabain required before the appearance of the first signs of atrial arrhythmia in anaesthetized guinea-pigs, but did not prevent ventricular arrhythmias." | 3.65 | The effect of bretylium on intracellular cardiac action potentials in relation to its anti-arrhythmic and local anaesthetic activity. ( Papp, JG; Vaughan Williams, EM, 1969) |
| "Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery." | 2.68 | Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery. ( Berg, EM; Levang, OW; Sellevold, OF, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (85.71) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WEGRIA, R | 1 |
| FRANK, CW | 1 |
| WANG, HH | 1 |
| MISRAHY, G | 1 |
| MILLER, R | 1 |
| KORNFELD, P | 1 |
| GRUMBACH, L | 1 |
| RIBERI, A | 1 |
| SIDERYS, H | 1 |
| SHUMACKER, HB | 1 |
| CAVALLINI, G | 1 |
| MILLA, E | 1 |
| RAVENNA, F | 1 |
| GRUMELLI, E | 1 |
| SCHIESSLE, W | 1 |
| NAHAS, GG | 1 |
| GHEORGHIU, P | 1 |
| STROESCU, V | 1 |
| SZEKERES, L | 1 |
| LENARD, G | 1 |
| WAX, SD | 1 |
| WEBB, WR | 1 |
| LESIUIS, Ie | 1 |
| GRIFFITHS, JC | 1 |
| SHEN, TC | 1 |
| LEE, ZW | 1 |
| JOHANSSON, BW | 2 |
| CHARDACK, WM | 1 |
| MARCHAND, P | 1 |
| VISENTINI, P | 1 |
| STEARNS, NS | 1 |
| MAISON, GL | 1 |
| STUTZMAN, JW | 1 |
| SCHWARTZ, SP | 1 |
| HALLINGER, L | 1 |
| IMPERIALLI, A | 1 |
| READ, JM | 1 |
| Sellevold, OF | 1 |
| Berg, EM | 1 |
| Levang, OW | 1 |
| Schmiedl, A | 2 |
| Schnabel, PA | 1 |
| Richter, J | 2 |
| Mall, G | 1 |
| Bretschneider, HJ | 1 |
| Gøtzsche, LS | 1 |
| Pedersen, EM | 1 |
| Paulsen, PK | 1 |
| Mustonen, PK | 1 |
| Hippeläinen, MJ | 1 |
| Pöyhönen, MJ | 1 |
| Rehnberg, LS | 1 |
| Stoletzki, S | 1 |
| Slama, R | 1 |
| Coumel, P | 1 |
| Motte, G | 1 |
| Gourgon, R | 1 |
| Waynberger, M | 1 |
| Touche, S | 1 |
| Chazov, EI | 1 |
| Lukomskiĭ, PE | 1 |
| Doshchitsin, VL | 1 |
| Alps, BJ | 1 |
| Hill, M | 1 |
| Fidler, K | 1 |
| Johnson, ES | 1 |
| Wilson, AB | 1 |
| Kato, H | 1 |
| Noguchi, Y | 1 |
| Takagi, K | 1 |
| Kirimli, B | 1 |
| Harris, LC | 1 |
| Safar, P | 1 |
| Kirchner, E | 1 |
| Papp, JG | 1 |
| Vaughan Williams, EM | 1 |
| Steinhaus, JE | 1 |
| Manni, C | 1 |
| Mazzoni, P | 1 |
| Staffen, A | 1 |
| Wolner, E | 1 |
2 reviews available for procaine and Ventricular Fibrillation
| Article | Year |
|---|---|
HEART BLOCK TREATED WITH AN IMPLANTABLE PACEMAKER. PAST EXPERIENCE AND CURRENT DEVELOPMENTS.
Topics: Adams-Stokes Syndrome; Blood Flow Velocity; Blood Pressure; Electrocardiography; Geriatrics; Heart; | 1964 |
[Treatment of arrhythmia in myocardial infarct].
Topics: Amides; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Cardiac Complexes, Premature; Cardiac G | 1968 |
3 trials available for procaine and Ventricular Fibrillation
| Article | Year |
|---|---|
Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery.
Topics: Adult; Aged; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Coronary Arter | 1995 |
Procaine and timing of aortic declamping affect ventricular reperfusion fibrillation.
Topics: Adult; Aged; Cardioplegic Solutions; Coronary Artery Bypass; Coronary Disease; Double-Blind Method; | 1996 |
[Ventricular tachycardia and "volley of ventricular spikes". Morphological frontiers between ventricular dysrhythmias].
Topics: Cardiac Complexes, Premature; Clinical Trials as Topic; Diagnosis, Differential; Electrocardiography | 1973 |
30 other studies available for procaine and Ventricular Fibrillation
| Article | Year |
|---|---|
A study of the usefulness and limitations of electrical countershock, cardiac massage, epinephrine and procaine in cardiac resuscitation from ventricular fibrillation.
Topics: Electric Countershock; Epinephrine; Heart Massage; Humans; Procaine; Resuscitation; Ventricular Fibr | 1953 |
The initiation of ventricular tachycardia and fibrillation by procaine in the isolated-perfused rabbit heart.
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction | 1956 |
Ventricular fibrillation in the hypothermic state. I. Prevention by sino-auricular node blockade.
Topics: Anesthesia; Anesthesia, Conduction; Anesthesiology; Humans; Procaine; Ventricular Fibrillation | 1956 |
[Defibrillatory effect of several substituted derivatives of phenoxyacetic acid].
Topics: Acetates; Arrhythmias, Cardiac; Cardiovascular Diseases; Procainamide; Procaine; Ventricular Fibrill | 1955 |
[Experimental study of electroshock therapy of ventricular fibrillation].
Topics: Cardiovascular Diseases; Convulsive Therapy; Electricity; Electroconvulsive Therapy; Epinephrine; He | 1956 |
[Anti-fibrillation substances].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Cinc | 1956 |
[Change in the fibrillation threshold of auricular and ventricular musculature of isolated mammalian heart after cooling and after administration of various pharmacological agents].
Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Con | 1960 |
Changes in cardiac excitability with anesthetization of the sino-auricular or atrio-ventricular node.
Topics: Atrioventricular Node; Benzenesulfonates; Cardiovascular Diseases; Heart; Humans; Procaine; Ventricu | 1960 |
[Acute disorders of the ventricular rhythm of the heart as terminal disorders and some possibilities for their treatment].
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Camphor; Cardiac Conduction System Disease; Coronary Disease | 1962 |
Reversal of ventricular fibrillation without an electrical defibrillator.
Topics: Chlorides; Defibrillators; Electric Countershock; Epinephrine; Heart Arrest; Humans; Procaine; Ventr | 1962 |
Further studies on the benzol-adrenaline cardio-ventricular fibrillation.
Topics: Benzene; Chlorpromazine; Epinephrine; Heart; Norepinephrine; Procaine; Thiamine; Ventricular Fibrill | 1962 |
THE EFFECT OF ACONITINE, ADRENALIN AND PROCAINE, AND CHANGES IN THE IONIC CONCENTRATION IN THE PRODUCTION OF VENTRICULAR FIBRILLATION IN A HIBERNATOR (HEDGEHOG) AND A NON-HIBERNATOR (GUINEA-PIG) AT DIFFERENT TEMPERATURES.
Topics: Aconitine; Aconitum; Animals; Epinephrine; Eulipotyphla; Guinea Pigs; Heart; Hedgehogs; Hibernation; | 1963 |
CARDIAC ARREST AND RESUSCITATION.
Topics: Calcium; Electric Stimulation Therapy; Epinephrine; Equipment and Supplies; Heart Arrest; Heart Mass | 1964 |
[Defibrillating action of lidocaine and novocaine].
Topics: Anesthetics; Anesthetics, Local; Electric Countershock; Lidocaine; Procaine; Ventricular Fibrillatio | 1955 |
Cardiac resuscitation from induced ventricular fibrillation; the influence of massage, procaine and electric shock.
Topics: Heart; Humans; Massage; Procaine; Resuscitation; Shock; Ventricular Fibrillation | 1951 |
Transient ventricular fibrillation. IV. The effects of procaine amide on patients with transient ventricular fibrillation during established auriculoventricular dissociation.
Topics: Cardiovascular Diseases; Heart Block; Procainamide; Procaine; Ventricular Fibrillation | 1952 |
Fatal ventricular fibrillation following procaine amide hydrochloride therapy; report of a case.
Topics: Cardiovascular Diseases; Procainamide; Procaine; Ventricular Fibrillation | 1952 |
Preservation of cardiac myocytes subjected to different preconditions: a comparative morphometric study of beating, fibrillating, and cardioplegically arrested canine hearts.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Dogs; Glucose; Heart Arrest, Induce | 1993 |
Lowered threshold for ventricular fibrillation in amiodarone-treated pigs undergoing cardiopulmonary bypass and cardioplegic arrest with St. Thomas' cardioplegic solution.
Topics: Amiodarone; Animals; Bicarbonates; Calcium Chloride; Cardiac Pacing, Artificial; Cardioplegic Soluti | 1993 |
Intercalated clear cells or pale cells in the sinus node of canine hearts? An ultrastructural study.
Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Dogs; Female; Glucose; Heart; Heart | 2000 |
Ventricular repolarization and fibrillation threshold in hibernating species.
Topics: Aconitine; Adrenergic Fibers; Animals; Body Temperature Regulation; Bundle-Branch Block; Calcium Chl | 1985 |
[Clinical significance and treatment of disorders of the cardiac rhythm in patients with myocardial infarct].
Topics: Adult; Aged; Amides; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, P | 1969 |
The reversal of experimental cardiac arrhythmias by indoramin (Wy 21901).
Topics: Amides; Anesthetics, Local; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Pressure; Cats; | 1971 |
Antiarrhythmic activity of 1-(7-indenyloxy)-3-isopropylaminopropane-2-ol hydrochloride (YB-2) and its optical isomers.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Depression, C | 1974 |
Drugs in cardiopulmonary resuscitation.
Topics: Alkalies; Animals; Anti-Arrhythmia Agents; Bicarbonates; Dogs; Epinephrine; Humans; Lidocaine; Norep | 1966 |
[Incidents in dental local anesthesia].
Topics: Anesthesia, Dental; Anesthesia, Local; Epinephrine; Humans; Hypersensitivity, Delayed; Hypersensitiv | 1971 |
The effect of bretylium on intracellular cardiac action potentials in relation to its anti-arrhythmic and local anaesthetic activity.
Topics: Action Potentials; Anesthetics, Local; Animals; Anura; Arrhythmias, Cardiac; Bretylium Compounds; Gu | 1969 |
Pharmacology of intravenous local anesthetics.
Topics: Anesthetics, Local; Autonomic Nervous System; Cardiovascular System; Central Nervous System; Electro | 1969 |
[Death and resuscitation in drowning].
Topics: Animals; Anticoagulants; Arrhythmias, Cardiac; Assisted Circulation; Blood Transfusion; Brain Death; | 1970 |
[Treatment of the most severe postoperative cardiac arrhythmias].
Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Digitoxin; Electrocardiography; Female; Humans; Lidocaine; | 1970 |