procaine has been researched along with Porphyrias in 3 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute intermittent porphyria is one of three severe hepatic porphyrias." | 5.27 | [Peridural anesthesia with procaine and fentanyl in a parturient with acute intermittent porphyria]. ( Deybach, JC; Durand, M; Joyau, M; Nordmann, Y; Parmentier, G, 1986) |
| "Acute intermittent porphyria is one of three severe hepatic porphyrias." | 1.27 | [Peridural anesthesia with procaine and fentanyl in a parturient with acute intermittent porphyria]. ( Deybach, JC; Durand, M; Joyau, M; Nordmann, Y; Parmentier, G, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MELLINGER, GW | 1 |
| PEARSON, CC | 1 |
| Joyau, M | 1 |
| Deybach, JC | 1 |
| Durand, M | 1 |
| Parmentier, G | 1 |
| Nordmann, Y | 1 |
| Duperrat, B | 1 |
| Seringe, P | 1 |
| Gajdos, A | 1 |
| Puissant, A | 1 |
| Pringuet, R | 1 |
3 other studies available for procaine and Porphyrias
| Article | Year |
|---|---|
Acute porphyria.
Topics: Humans; Porphyria, Acute Intermittent; Porphyrias; Procaine | 1953 |
[Peridural anesthesia with procaine and fentanyl in a parturient with acute intermittent porphyria].
Topics: Acute Disease; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Female; Fentanyl; Humans; Obste | 1986 |
[Erythropoietic protoporphyria caused at the age of 4 by a local novocaine anesthesia].
Topics: Anesthesia, Local; Child, Preschool; Humans; Male; Photosensitivity Disorders; Porphyrias; Procaine; | 1972 |