procaine has been researched along with Parkinson Disease in 15 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohsaka, M | 1 |
| Oeda, T | 1 |
| Umemura, A | 1 |
| Tomita, S | 1 |
| Park, K | 1 |
| Yamamoto, K | 1 |
| Sugiyama, H | 1 |
| Sawada, H | 1 |
| COOPER, IS | 4 |
| LYONNET, JH | 1 |
| BRAGE, D | 1 |
| PADACE, A | 1 |
| NARABAYASHI, H | 1 |
| OKUMA, T | 1 |
| SHIKIBA, S | 1 |
| POLOUKHINE, N | 2 |
| TORRES, M | 2 |
| ASLAN, A | 1 |
| KJELLBERG, RN | 1 |
| TODD, DP | 1 |
| SCHWAB, RS | 1 |
| ENGLAND, AC | 1 |
| LANCE, JW | 2 |
| SWEET, WH | 1 |
| SCARDIGLI, G | 1 |
| GUIDI, G | 1 |
| Nagasaki, H | 1 |
| Nakamura, R | 1 |
| Bathien, N | 1 |
| Rondot, P | 1 |
| Andrews, CJ | 1 |
| Burke, D | 1 |
| Takamori, M | 1 |
| Jurna, I | 1 |
| Nell, T | 1 |
| Schreyer, I | 1 |
| Gjerris, F | 1 |
15 other studies available for procaine and Parkinson Disease
| Article | Year |
|---|---|
Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo-controlled pilot trial.
Topics: Anesthetics, Local; Apraxias; Eyelids; Female; Humans; Male; Parkinson Disease; Pilot Projects; Proc | 2018 |
Procaine injection of the globus pallidus in Parkinsonism.
Topics: Basal Ganglia; Globus Pallidus; Humans; Parkinson Disease; Parkinsonian Disorders; Procaine | 1954 |
Chemopallidectomy: an investigative technique in geriatric parkinsonians.
Topics: Aged; Basal Ganglia; Disease; Parkinson Disease; Procaine | 1955 |
[Novocaine infiltration of the globus pallidus in Parkinson's disease].
Topics: Basal Ganglia; Biophysical Phenomena; Globus Pallidus; Humans; Parkinson Disease; Procaine | 1954 |
Procaine oil blocking of the globus pallidus.
Topics: Anesthesia; Anesthesia, Conduction; Anesthesiology; Basal Ganglia; Globus Pallidus; Humans; Parkinso | 1956 |
Effects of lesions in the putamen on involuntary movements and rigidity in Parkinson's disease.
Topics: Alcohols; Basal Ganglia; Dyskinesias; Humans; Muscle Rigidity; Parkinson Disease; Procaine; Putamen | 1956 |
Effects of lesions in the putamen on involuntary movements and rigidity in Parkinson's disease.
Topics: Alcohols; Basal Ganglia; Dyskinesias; Humans; Muscle Rigidity; Parkinson Disease; Procaine; Putamen | 1956 |
Effects of lesions in the putamen on involuntary movements and rigidity in Parkinson's disease.
Topics: Alcohols; Basal Ganglia; Dyskinesias; Humans; Muscle Rigidity; Parkinson Disease; Procaine; Putamen | 1956 |
Effects of lesions in the putamen on involuntary movements and rigidity in Parkinson's disease.
Topics: Alcohols; Basal Ganglia; Dyskinesias; Humans; Muscle Rigidity; Parkinson Disease; Procaine; Putamen | 1956 |
[Studies of the action of novocaine (substance H3): eutrophic action and rejuvenation].
Topics: Aged; Arteriosclerosis Obliterans; Basal Ganglia; Basal Ganglia Diseases; Disease; Eyelids; Humans; | 1958 |
Gait improvement in parkinsonian patients by gamma motor neuron suppression.
Topics: Gait; Humans; Motor Neurons, Gamma; Neurons; Parkinson Disease; Phenols; Procaine | 1961 |
[Therapy with Gerovital H3 in the diseases of senescence and of old age].
Topics: Aged; Aged, 80 and over; Arteriosclerosis; Arthritis; Depression; Depressive Disorder; Geriatrics; P | 1962 |
Rhythm formation and its disturbances--a study based upon periodic response of a motor output system.
Topics: Arm; Feedback; Humans; Models, Neurological; Motor Skills; Muscles; Nerve Block; Parkinson Disease; | 1982 |
Reciprocal continuous inhibition in rigidity of Parkinsonism.
Topics: Adult; Aged; H-Reflex; Humans; Levodopa; Middle Aged; Muscle Rigidity; Muscles; Neural Inhibition; P | 1977 |
The response to muscle stretch and shortening in Parkinsonian rigidity.
Topics: Action Potentials; Aged; Elbow; Electromyography; Fatigue; Female; Humans; Ischemia; Male; Middle Ag | 1972 |
H reflex study in upper motoneuron diseases.
Topics: Adolescent; Adult; Aged; Child; Chorea; Dystonia Musculorum Deformans; Electric Stimulation; Female; | 1967 |
Motor disturbance induced by tremorine and oxotremorine.
Topics: Acetylcholine; Amines; Animals; Atropine; Biperiden; Brain; Bridged-Ring Compounds; Chlorpromazine; | 1970 |
Transitory procaine-induced Parkinsonism.
Topics: Chronic Disease; Dihydroxyphenylalanine; Female; Humans; Middle Aged; Parkinson Disease; Parkinson D | 1971 |