Page last updated: 2024-11-03

procaine and Pain, Postoperative

procaine has been researched along with Pain, Postoperative in 58 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"The preoperative and postoperative pain scores were compared using nonparametric tests."3.11Efficacy and Safety of Oxybuprocaine Hydrochloride Gel in Alleviating Pain during Male Urethral Catheterization: A Single-Center Randomized Controlled Study. ( Chen, H; Chen, X; Cui, Y; Dong, Y; Dong, Z; Qu, X; Zhang, L, 2022)
"We evaluated the dose-response relationship of 2-chloroprocaine for lower limb outpatient procedure in 45 ASA physical status I-II outpatients undergoing elective lower limb surgery under spinal anesthesia, with 30 mg (group Chlor-30, n = 15), 40 mg (group Chlor-40, n = 15), or 50 mg (group Chlor-50, n = 15) of 1% preservative free 2-chloroprocaine."2.72Intrathecal 2-chloroprocaine for lower limb outpatient surgery: a prospective, randomized, double-blind, clinical evaluation. ( Benassi, C; Berti, M; Casati, A; Danelli, G; Fanelli, A; Fanelli, G; Fioro, A; Petronella, G, 2006)
"Bupivacaine drops were effective in providing deep topical anesthesia."2.71Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops. ( Macky, TA; Samir, MK; Soliman, MM, 2004)
"Nalbuphine appears to be a disappointing agent for epidural use after Caesarean delivery."2.67Epidural nalbuphine for analgesia following caesarean delivery: dose-response and effect of local anaesthetic choice. ( Camann, WR; Datta, S; Gilbertson, LI; Hurley, RH; Long, ML, 1991)
"When patients first complained of postoperative pain in the recovery room, they were given either fentanyl 50 micrograms or butorphanol 2 mg, epidurally, in a randomized, blinded fashion."2.67Chloroprocaine antagonism of epidural opioid analgesia: a receptor-specific phenomenon? ( Camann, WR; Datta, S; Gilbertson, LI; Hartigan, PM; Johnson, MD, 1990)
"Chloroprocaine is an effective local anaesthetic in the erector spinae compartment, which has not been previously reported."1.56Erector spinae catheter for post-thoracotomy pain control in a premature neonate. ( Flaherty, J; Hess, D; Horvath, B; Swenson Schalkwyk, A, 2020)
"Early postoperative pain occurred more frequently and earlier after spinal anaesthesia with chloroprocaine."1.51Using chloroprocaine for spinal anaesthesia in outpatient knee-arthroscopy results in earlier discharge and improved operating room efficiency compared to mepivacaine and prilocaine. ( Gebhardt, V; Hausen, S; Schmittner, MD; Weiss, C, 2019)
"Chloroprocaine is an ester local anesthetic that has an extremely short plasma half-life in infants as well as adults."1.43Continuous chloroprocaine infusion for thoracic and caudal epidurals as a postoperative analgesia modality in neonates, infants, and children. ( Aldrink, J; Bhalla, T; Iliev, P; Martin, D; Tobias, J; Tripi, J; Veneziano, G, 2016)
" Duration of epidural infusion did not influence dosing requirement, suggesting the absence of drug tachyphylaxis."1.42Evaluation of prolonged epidural chloroprocaine for postoperative analgesia in infants. ( Bielsky, AR; Murphy, ME; Reiter, PD; Ross, EL, 2015)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199023 (39.66)18.7374
1990's7 (12.07)18.2507
2000's11 (18.97)29.6817
2010's12 (20.69)24.3611
2020's5 (8.62)2.80

Authors

AuthorsStudies
Dong, Z1
Qu, X1
Zhang, L1
Chen, X1
Dong, Y1
Chen, H1
Cui, Y1
Greco, C1
Boretsky, KR1
Gadsden, JC1
Sata, S1
Bullock, WM1
Kumar, AH1
Grant, SA1
Dooley, JR1
Swenson Schalkwyk, A1
Flaherty, J1
Hess, D1
Horvath, B1
Relland, LM1
Beltran, R1
Kim, SS1
Bapat, R1
Shafy, S1
Uffman, J1
Maitre, NL1
Tobias, JD1
Veneziano, G2
Sweet, E1
Shusterman, CS1
Nedeljkovic, MS1
Solodiuk, JC1
Gebhardt, V2
Zawierucha, V1
Schöffski, O1
Schwarz, A1
Weiss, C2
Schmittner, MD2
Hausen, S1
Hofmann, K1
Rauh, A1
Harlizius, J1
Weiß, C1
Scholz, T1
Schulze-Horsel, T1
Escribano, D1
Ritzmann, M1
Zöls, S1
Breebaart, MB1
Teune, A1
Sermeus, LA1
Vercauteren, MP1
Ross, EL1
Reiter, PD1
Murphy, ME1
Bielsky, AR1
Muhly, WT1
Gurnaney, HG1
Kraemer, FW1
Ganesh, A1
Maxwell, LG1
Iliev, P1
Tripi, J1
Martin, D1
Aldrink, J1
Bhalla, T1
Tobias, J1
Malek, I1
Romdhane, O1
Sayadi, J1
Mekni, M1
Fekih, O1
Zghal, I1
Nacef, L1
Xu, H1
Li, H1
Zuo, Y1
Yang, B1
Tian, Y1
Guo, Q1
Xu, J1
Wu, C1
Mandelcorn, ED1
McCartney, CJ1
Mandelcorn, MS1
Muqit, MM1
Marcellino, GR1
Gray, JC1
McLauchlan, R1
Henson, DB1
Young, LB1
Patton, N1
Charles, SJ1
Turner, GS1
Stanga, PE1
El Rami, H1
Fadlallah, A1
Fahd, D1
Fahed, S1
Mahfouz, AK1
Nabawi, KS1
JAY, JB1
SEELEY, SF1
LEWIS, DL1
THOMPSON, WA1
PICHA, E1
WEGHAUPT, K1
MARKS, RF1
NYLANDER, PE1
DORKEN, N1
O'DONOVAN, D1
ROWLANDSON, R1
TOMASEO, I1
VINCENTI, F1
GIGLIO, AL1
INDORANTE, G1
TARSITANI, D1
HOLLER, W1
KOLE, W1
Sauder, G1
Jonas, JB1
MORITSCH, P1
Soliman, MM1
Macky, TA1
Samir, MK1
Gorskiĭ, VA1
Shurkalin, BK1
Kakurin, SN1
Rzhebaev, KE1
Karakhanova, GV1
Hess, PE1
Snowman, CE1
Hahn, CJ1
Kunze, LJ1
Ingold, VJ1
Pratt, SD1
Casati, A1
Danelli, G1
Berti, M1
Fioro, A1
Fanelli, A1
Benassi, C1
Petronella, G1
Fanelli, G1
Korhonen, AM1
Benatar-Haserfaty, J1
Monleón de la Calle, MP1
Sanz-López, A1
Muriel García, A1
Rao, SK1
Wong, VW1
Cheng, AC1
Lam, PT1
Lam, DS1
Brooks, GZ1
Donchin, Y1
Collins, JG1
Kitahata, LM1
Jefferson, SA1
Parris, WC1
Gerlock, AJ1
MacDonell, RC1
Goranson, BD1
Lang, S1
Cassidy, JD1
Dust, WN1
McKerrell, J1
Anders, N2
Heuermann, T2
Rüther, K1
Hartmann, C2
Tay, SK1
Soong, SL1
Choo, BM1
Rieck, P1
Akhundzhanov, BA1
Dadaev, ShA1
Mel'kumov, RS1
Sturm, V1
Kröger, M1
Penzholz, H1
Huntoon, M1
Eisenach, JC2
Boese, P1
Schlairet, TJ1
Dobson, CE1
Hood, DH1
Camann, WR2
Hurley, RH1
Gilbertson, LI2
Long, ML1
Datta, S2
Hartigan, PM1
Johnson, MD1
Fibuch, EE1
Opper, SE1
Kostova, S1
Boĭcheva, A1
Gavrilova, N1
Petrova, B1
Loeb, SA1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Erector Spinae Plane Block (ESP) Versus Thoracic Epidural Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS) in Pediatric Population; a Randomized, Controlled Study[NCT04878341]74 participants (Anticipated)Interventional2021-07-31Not yet recruiting
Influence of Spinal or Intravenous Dexmedetomidine on Spinal Anesthesia With Chloroprocaine and Bladder Function in Day-case Surgery. A Double Blind Randomized Study.[NCT02282319]Phase 4150 participants (Anticipated)Interventional2014-10-31Completed
An Observational Prospective Study of Comparing Pain Responses With Pattern Laser Platform and Conventional Laser System During the Panretinal Photocoagulation in Proliferative Diabetic Retinopathy[NCT02645383]30 participants (Actual)Interventional2014-05-31Completed
Effects of Methylprednisolone Plus Ropivacaine Infiltration Before Wound Closure on Laminoplasty or Laminectomy[NCT04493463]Phase 4132 participants (Actual)Interventional2020-07-31Completed
Clinical Comparison of Two Anesthetic Preparations for Intravitreal Injection[NCT01087489]53 participants (Actual)Interventional2010-04-30Completed
Comparison Between 2% Lidocaine Gel and 5% Tetracaine Eye Drop as Topical Anesthesia in Phacoemulsification[NCT03143452]72 participants (Actual)Interventional2016-12-01Completed
Spinal Anesthesia With Bupivacaine or 2-chloroprocaine for Outpatient Elective Surgery: a Prospective, Randomized, Double-blind Comparison.[NCT00845962]106 participants (Actual)Interventional2009-02-28Completed
Hemodynamic Effect of Intrathecal Clonidine in Hypertensive Subjects: A Pilot Study to Assess Its Effectiveness in Hypertensive Subjects With Poor Blood Pressure Control (Phase II)[NCT01297335]Phase 210 participants (Actual)Interventional2011-02-28Completed
Interaction Between Epidural 2-chloroprocaine and Epidural Morphine: Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia[NCT00487084]136 participants (Actual)Interventional2004-08-31Completed
Effect of Epidural Dexmedetomidine VS Nalbuphine for Labor Analgesia[NCT05327088]Phase 264 participants (Actual)Interventional2021-09-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Discomfort Level and Patient Satisfaction With the Preparation Protocol and Intravitreal Injection

"Discomfort according to the Eye Sensation Scale: 1-none, 2- mild, 3- moderate, 4- severe, 5- extremely severe~Patient satisfaction scale: 1=very unsatisfied, 2=unsatisfied, 3=neutral, 4=satisfied, 5= extremely satisfied" (NCT01087489)
Timeframe: immediately after injection, 1- hour later, and next day

,
Interventionunits on a scale (Mean)
Discomfort during anesthetic preparationDiscomfort during needle penetrationSatisfaction with entire prep and injectionDiscomfort 1 h after injectionDiscomfort day after injectionNext day satisfaction with injection
3.5% Ophthalmic Lidocaine Gel2.092.04.52.11.64.3
4% Liquid Lidocaine Method2.11.74.32.41.84.3

Intraocular Pressure Change After Intravitreal Injection With Each Anesthetic Method, Results Reported in mmHg

intraocular pressure (IOP) was measured immediately after the injection, and at 5, 10, and 15 minutes after the injection (until it was 30 mmHg or below). Prior to injection IOP and post-injection IOP were compared to find the IOP change after injection. (NCT01087489)
Timeframe: immediately after injection, at 5, 10, 15 minutes

,
InterventionmmHg (Mean)
baseline IOP before injectionIOP change after 0.05 cc injection
3.5% Ophthalmic Lidocaine Gel15.930.9
4% Liquid Lidocaine Method15.525.7

Presence and Severity of Keratopathy and the Size of Subconjunctival Hemorrhage

"Presence of corneal staining after the injection:~Quadrants of fluorescein staining: 0 1 2 3 4~Density of staining: 0- None 1- Mild 2- Moderate 3- Severe 4- corneal abrasion~Size of subconjunctival hemorrhage:~in clock hours" (NCT01087489)
Timeframe: within 10 minutes of the injection

,
Interventionunits on a scale (Mean)
Corneal fluorescein stainingDensity of corneal staining
3.5% Ophthalmic Lidocaine Gel2.31.3
4% Liquid Lidocaine Method3.01.9

Change in Blood Pressure After Intrathecal Injection of Clonidine.

"Subjects baseline blood pressure (systolic blood pressure (SBP), and diastolic blood pressure (DBP)), and blood pressures after clonidine injection was compared against baseline to assess efficacy of clonidine in refractory hypertensive subjects. Subject's blood pressure was monitored continuously after intrathecal injection of clonidine until subjects blood pressure nadir and return to pre clonidine injection level. The mean value reported below are the average changes in blood pressure from baseline (pre clonidine injection) in both SBP and DBP during post clonidine injection blood pressure monitoring for 4 hours.~Blood pressure measurements were collected every 10 minutes for first hour after injection, and every 15 minutes after the first hour, up to 4 hours were averaged to report the change from baseline." (NCT01297335)
Timeframe: Baseline, Every 10 Minutes for first hour after clonidine injection, and every 15 minutes after first hour, until 4 hours after clonidine injection

Interventionmm Hg (Mean)
Change in mean SBP after clonidine injectionChange in DBP after clonidine injection
Intrathecal Clonidine7937

Changes in Visual Analogue Scale (VAS) Ratings of Sedation and Sensation of Dry Mouth Reported by the Subjects, Pre and 1 Hour Post Injection

Subjects were asked to rate severity of two of the most common side effects of clonidine, sedation and sensation of dry mouth, at pre and post (1 hour after) intrathecal administration of clonidine. The mean changes between pre and post injection VAS ratings of sedation and sensation of dry mouth are reported below. The VAS scale ranges from 1 to 10 cm, with higher values indicating higher level of sedation and higher level of dry mouth. (NCT01297335)
Timeframe: Before clonidine injection (Baseline), and at 1 hour after clonidine injection.

Interventioncm (Mean)
Change in level of sedationChange in sensation of dry mouth
Intrathecal Clonidine3.363.47

Likert Scale Pain Rating

Likert scale is 11 point digital pain rating system that asks subjects to rate their pain from 0 to 10. Rating of 0 means no pain at all, and in increasing order, 10 would mean worst pain imaginable/ unbearable pain. (NCT01297335)
Timeframe: Pre-dose and 1 hour post injection.

Interventionunits on a scale (Mean)
Pre-injection average Likert scorePost-injection average Likert score
Intrathecal Clonidine6.53.6

Duration of Continuing Analgesia

Time to first request for supplemental analgesia (NCT00487084)
Timeframe: 48 hours

Interventionhours (Median)
Morphine - 2 Chloroprocaine - Saline (MCS)28.6
Saline-2 Chloroprocaine - Morphine (SCM)2.2
Saline - Lidocaine - Morphine (SLM)25.8

Supplemental Analgesia in First 48 Hours

Participants requesting supplemental analgesia in first 48 hours (NCT00487084)
Timeframe: 48 hours

InterventionParticipants (Number)
Morphine - 2 Chloroprocaine - Saline (MCS)12
Saline-2 Chloroprocaine - Morphine (SCM)8
Saline - Lidocaine - Morphine (SLM)12

Supplemental Analgesia in First 90 Minutes

Participants requesting supplemental analgesia in the first 90 minutes following study drug (NCT00487084)
Timeframe: 90 min

Interventionparticipants (Number)
Morphine - 2 Chloroprocaine - Saline (MCS)0
Saline-2 Chloroprocaine - Morphine (SCM)10
Saline - Lidocaine - Morphine (SLM)0

Verbal Rating Score (0 to 10) for Pain (VRPS)

Verbal Rating Pain Score (VRPS) at time of post-anesthesia recovery room entry, where 0 = no pain and 10 = worst pain imaginable (NCT00487084)
Timeframe: At recovery room entry

InterventionScores on a scale (Median)
Morphine - 2 Chloroprocaine - Saline (MCS)2
Saline-2 Chloroprocaine - Morphine (SCM)2
Saline - Lidocaine - Morphine (SLM)0

Reviews

3 reviews available for procaine and Pain, Postoperative

ArticleYear
Nurse Practitioner-Administered Chloroprocaine in Children with Postoperative Pain.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2018, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthetics, Local; Child; Child, Preschool; Female; Humans

2018
Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:11

    Topics: Administration, Topical; Anesthetics, Local; Diabetic Retinopathy; Female; Humans; Light Coagulation

2010
Use of spinal anaesthesia in day surgery.
    Current opinion in anaesthesiology, 2006, Volume: 19, Issue:6

    Topics: Ambulatory Surgical Procedures; Analgesics; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthet

2006

Trials

22 trials available for procaine and Pain, Postoperative

ArticleYear
Efficacy and Safety of Oxybuprocaine Hydrochloride Gel in Alleviating Pain during Male Urethral Catheterization: A Single-Center Randomized Controlled Study.
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Adult; Anesthetics, Local; Humans; Lubricants; Male; Mineral Oil; Pain Measurement; Pain, Postoperat

2022
The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study.
    Korean journal of anesthesiology, 2020, Volume: 73, Issue:5

    Topics: Aged; Analgesia; Anesthetics, Local; Arthroplasty, Replacement, Knee; Autonomic Nerve Block; Double-

2020
Spinal anaesthesia with chloroprocaine 1% versus total intravenous anaesthesia for outpatient knee arthroscopy: A randomised controlled trial.
    European journal of anaesthesiology, 2018, Volume: 35, Issue:10

    Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics, Local; Arthroscopy; Dru

2018
Intrathecal chloroprocaine vs. lidocaine in day-case surgery: recovery, discharge and effect of pre-hydration on micturition.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:2

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthe

2014
[Cataract surgery with topical anesthesia in adults under 30 years of age: Preliminary study].
    Journal francais d'ophtalmologie, 2016, Volume: 39, Issue:10

    Topics: Administration, Topical; Adult; Anesthesia, Local; Cataract Extraction; Female; Humans; Male; Pain M

2016
A multicenter study of the analgesic effects of epidural chloroprocaine after lower limb orthopedic surgery.
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Epidural;

2016
A controlled clinical interventional trial comparing 2% chloroprocaine-bupivicaine versus 2% lidocaine-bupivicaine for retrobulbar anesthesia in scleral buckling surgery.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined; Anesthetics, L

2009
Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:11

    Topics: Administration, Topical; Anesthetics, Local; Diabetic Retinopathy; Female; Humans; Light Coagulation

2010
Preemptive analgesia in rhegmatogenous retinal detachment surgery: is it effective?
    Retina (Philadelphia, Pa.), 2002, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Analgesia; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anest

2002
Topical versus peribulbar anaesthesia for cataract surgery.
    Acta ophthalmologica Scandinavica, 2003, Volume: 81, Issue:6

    Topics: Administration, Topical; Aged; Anesthesia, Local; Anesthetics, Local; Capsulorhexis; Female; Humans;

2003
Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Capsulorhexis; Female; Gels; Humans; Lidoc

2004
Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Capsulorhexis; Female; Gels; Humans; Lidoc

2004
Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Capsulorhexis; Female; Gels; Humans; Lidoc

2004
Comparative clinical trial of topical anesthetic agents in cataract surgery: lidocaine 2% gel, bupivacaine 0.5% drops, and benoxinate 0.4% drops.
    Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:8

    Topics: Aged; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Capsulorhexis; Female; Gels; Humans; Lidoc

2004
[A new method of anaesthesia in laparoscopic cholecystectomy].
    Khirurgiia, 2005, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, La

2005
Chloroprocaine may not affect epidural morphine for postcesarean delivery analgesia.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Obstetrical; Ane

2006
Intrathecal 2-chloroprocaine for lower limb outpatient surgery: a prospective, randomized, double-blind, clinical evaluation.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:1

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Local;

2006
A comparison of three regional anaesthesia techniques for outpatient knee arthroscopy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Loca

1997
Clinical and electrophysiologic results after intracameral lidocaine 1% anesthesia: a prospective randomized study.
    Ophthalmology, 1999, Volume: 106, Issue:10

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Electroretinography; Humans; Len

1999
Is routine procaine spirit application necessary in the care of episiotomy wound?
    Singapore medical journal, 1999, Volume: 40, Issue:9

    Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Baths

1999
[Peribulbar anesthesia versus topical anesthesia in cataract surgery: comparison of the postoperative course].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2000, Volume: 97, Issue:3

    Topics: Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Humans; Lidocaine; Pain, Postoperative;

2000
Epidural clonidine after cesarean section. Appropriate dose and effect of prior local anesthetic.
    Anesthesiology, 1992, Volume: 76, Issue:2

    Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupiv

1992
Effect of prior anesthetic solution on epidural morphine analgesia.
    Anesthesia and analgesia, 1991, Volume: 73, Issue:2

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Sect

1991
Epidural nalbuphine for analgesia following caesarean delivery: dose-response and effect of local anaesthetic choice.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:6

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; A

1991
Chloroprocaine antagonism of epidural opioid analgesia: a receptor-specific phenomenon?
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Butorphanol; Cesarean Sectio

1990

Other Studies

34 other studies available for procaine and Pain, Postoperative

ArticleYear
Continuous chloroprocaine paravertebral infusions for postoperative analgesia in infants and very young children.
    Paediatric anaesthesia, 2020, Volume: 30, Issue:9

    Topics: Analgesia; Analgesia, Epidural; Anesthetics, Local; Child; Child, Preschool; Humans; Infant; Pain, P

2020
Erector spinae catheter for post-thoracotomy pain control in a premature neonate.
    BMJ case reports, 2020, Sep-07, Volume: 13, Issue:9

    Topics: Anesthetics, Local; Catheterization; Female; Humans; Infant, Newborn; Infant, Premature; Nerve Block

2020
Continuous epidural chloroprocaine after abdominal surgery is associated with lower postoperative opioid exposure in NICU infants.
    Journal of pediatric surgery, 2022, Volume: 57, Issue:4

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Humans; Infant; Infant, Newborn; Intens

2022
Using chloroprocaine for spinal anaesthesia in outpatient knee-arthroscopy results in earlier discharge and improved operating room efficiency compared to mepivacaine and prilocaine.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019, Volume: 27, Issue:9

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthesia, Spinal; Anesthetics, Loc

2019
[Pain and distress responses of suckling piglets to injection and castration under local anaesthesia with procaine and lidocaine - Part 1: Cortisol, chromogranin A, wound healing, weights, losses].
    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2019, Volume: 47, Issue:2

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Animals, Suckling; Body Weight; Chromogranin A; Hand

2019
Evaluation of prolonged epidural chloroprocaine for postoperative analgesia in infants.
    Journal of clinical anesthesia, 2015, Volume: 27, Issue:6

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Child, Preschool;

2015
A retrospective comparison of ropivacaine and 2-chloroprocaine continuous thoracic epidural analgesia for management of postthoracotomy pain in infants.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:11

    Topics: Amides; Analgesia, Epidural; Anesthetics, Local; Cohort Studies; Female; Humans; Infant; Infant, New

2015
Continuous chloroprocaine infusion for thoracic and caudal epidurals as a postoperative analgesia modality in neonates, infants, and children.
    Paediatric anaesthesia, 2016, Volume: 26, Issue:1

    Topics: Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; Child, Preschool; Female; Humans; Inf

2016
Patient-perceived pain during laser in situ keratomileusis: comparison of fellow eyes.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:3

    Topics: Adult; Blood Pressure; Diazepam; Eye Pain; Female; Humans; Hypnotics and Sedatives; Intraocular Pres

2012
Intravenous use of procaine to relieve postoperative pain.
    United States Armed Forces medical journal, 1952, Volume: 3, Issue:10

    Topics: Humans; Injections, Intravenous; Pain; Pain, Postoperative; Postoperative Care; Procaine

1952
Reduction of post-operative pain.
    British medical journal, 1953, May-02, Volume: 1, Issue:4817

    Topics: Pain Management; Pain, Postoperative; Procaine

1953
[Postoperative pain control by intravenous novocaine].
    Wiener medizinische Wochenschrift (1946), 1953, Jul-18, Volume: 103, Issue:29-30

    Topics: Humans; Pain; Pain, Postoperative; Procaine

1953
The effect of efocaine in the control of postoperative pain.
    The Laryngoscope, 1953, Volume: 63, Issue:9

    Topics: Adenoids; Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Pain; Pain Management; Pa

1953
The problem of postoperative pain in thoracic surgery.
    Acta chirurgica Scandinavica, 1953, Dec-29, Volume: 106, Issue:4

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Pain; Pain Management; Pain, Postop

1953
[Control of postoperative pain by efocaine].
    Turk Tip Cemiyeti mecmuasi, 1954, Volume: 20, Issue:1

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Pain; Pain Management; Pain

1954
Efocaine in the treatment of postoperative pain.
    Journal of the Irish Medical Association, 1954, Volume: 34, Issue:205

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Pain; Pain Management; Pain, Postop

1954
Postoperative pain; attempted control with a long-lasting local anaesthetic.
    Lancet (London, England), 1954, Jul-24, Volume: 267, Issue:6830

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthetics, Local; Pain; Pain Mana

1954
[Procaine value in relieving the postoperative pain].
    Acta chirurgica Iugoslavica, 1954, Volume: 1, Issue:1-2

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Pain; Pain, Postoperative; Postoperative Ca

1954
[Anesthesia of the laparotomy wound as a new method of treating postoperative pain].
    Minerva ginecologica, 1954, Apr-15, Volume: 6, Issue:7

    Topics: Abdomen; Analgesia; Anesthesia; Anesthesia and Analgesia; Female; Humans; Laparotomy; Pain; Pain, Po

1954
[The use of a new local anesthetic with prolonged action for the control of postoperative pain].
    Minerva anestesiologica, 1954, Volume: 20, Issue:8

    Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Anesthetics, Loc

1954
[Use of delayed-absorption anesthetics in therapy of postoperative pain in tonsillectomy].
    L'Oto-rino-laringologia italiana, 1954, Volume: 22, Issue:4

    Topics: Adenoids; Aminobenzoates; Anesthetics; Pain; Pain, Postoperative; Palatine Tonsil; Procaine; Tonsill

1954
[The problem of temporary nerve block in postoperative pain states].
    Deutsche Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt fur die gesamte Zahn-, Mund-, und Kieferheilkunde, 1955, Volume: 22, Issue:3-4

    Topics: Alcohols; Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Mandibular Nerve; Nerve Block; Ne

1955
[Postoperative pain control after thoracic surgery with depolipone].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1955, Volume: 10, Issue:1

    Topics: Pain, Postoperative; Procaine; Thoracic Surgery; Thoracic Surgical Procedures; Thorax

1955
[Prevention of postoperative pain with oily anesthetic solutions].
    Wiener medizinische Wochenschrift (1946), 1951, Feb-24, Volume: 101, Issue:8

    Topics: Anesthetics; Biomedical Research; General Surgery; Humans; Pain, Postoperative; Procaine

1951
[Outpatient external dacryocystorhinostomy under regional anesthesia and sedation].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:1

    Topics: Aged; Ambulatory Surgical Procedures; Analgesia; Blood Loss, Surgical; Bupivacaine; Dacryocystorhino

2007
Topical anesthesia-induced keratopathy after laser-assisted subepithelial keratectomy.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:8

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Corneal Diseases; Female; Humans; Keratectomy, Subepit

2007
Epidural morphine does not affect the duration of action of epidural 2-chloroprocaine following Caesarean section.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:6

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Double-Blind Method; Drug Interactions; Female; Human

1983
Intra-arterial chloroprocaine for the control of pain associated with partial splenic embolization.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:2

    Topics: Adult; Anesthetics, Local; Embolization, Therapeutic; Humans; Hypersplenism; Injections, Intra-Arter

1981
[Comparative evaluation of long-term novocaine block of reflexogenic zones of the abdominal organs].
    Khirurgiia, 1979, Issue:10

    Topics: Colon; Evaluation Studies as Topic; Humans; Liver; Mesentery; Nerve Block; Pain, Postoperative; Proc

1979
Letter: Caudal block for post-operative pain relief in children.
    Anaesthesia, 1975, Volume: 30, Issue:1

    Topics: Adult; Anesthesia, Spinal; Bupivacaine; Child; Circumcision, Male; Epinephrine; Humans; Ketamine; Ma

1975
[Problems of peripheral nerve surgery in amputation stump pain and phantom limbs].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1975, Volume: 46, Issue:9

    Topics: Amputation Stumps; Ethanol; Follow-Up Studies; Humans; Pain, Postoperative; Peripheral Nerves; Phant

1975
Back pain following epidurally administered Nesacaine-MPF.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:1

    Topics: Adult; Anesthetics, Local; Back Pain; Female; Humans; Injections, Epidural; Male; Middle Aged; Pain,

1989
[Analgesia in the postoperative period for severely ill children].
    Khirurgiia, 1987, Volume: 40, Issue:3

    Topics: Analgesia; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Ether; Hemodynamics; Humans;

1987
Hemorrhoidectomy: method for elimination of post-operative pain due to sphincter spasm.
    American journal of proctology, 1974, Volume: 25, Issue:6

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Anesthetics; Anus Diseases; Dibucaine; Follow-Up Studies; Hemor

1974