procaine has been researched along with Neoplasms in 21 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, X | 1 |
| Qi, T | 1 |
| Yang, M | 1 |
| Zhang, W | 1 |
| Kong, C | 1 |
| Hao, M | 1 |
| Wang, Y | 1 |
| Zhang, H | 1 |
| Yang, B | 1 |
| Yang, J | 1 |
| Jiang, J | 1 |
| Linnekamp, JF | 1 |
| Butter, R | 1 |
| Spijker, R | 1 |
| Medema, JP | 1 |
| van Laarhoven, HWM | 1 |
| NULSEN, FE | 1 |
| GRANT, F | 1 |
| HEYMACH, W | 1 |
| MOORE, DC | 1 |
| BATTEZZATI, M | 1 |
| BINDA, B | 1 |
| SIGWALD, J | 1 |
| BOUTTIER, D | 1 |
| PIOT, C | 1 |
| GUIBERT, M | 1 |
| PAYOT, J | 1 |
| DARGENT, M | 1 |
| MANSUY, L | 1 |
| IANKOVSKII, GA | 1 |
| SEGLINSH, KIa | 1 |
| ZAKENFELD, GK | 1 |
| KUNDZINIA, Ia | 1 |
| MARX, GF | 1 |
| SCHEINBERG, L | 1 |
| ROMNEY, SL | 1 |
| AIZENBERG, VP | 1 |
| KARAEVA, F | 1 |
| PAN, PC | 1 |
| JEN, YF | 1 |
| WANG, YY | 1 |
| KAO, YS | 1 |
| SCHMOLLING, H | 1 |
| MANDL, F | 1 |
| PAUL, F | 1 |
| GYRI, W | 1 |
| JELINEK, R | 1 |
| BUCAILLE, M | 1 |
| ROGE, R | 1 |
| GUILLAUME, J | 1 |
| RIBADEAU-DUMAS, C | 1 |
| Pavlova, ZV | 1 |
| Kazhlaeva, UI | 1 |
| Isaev, MS | 1 |
| Pongratz, A | 1 |
| Taufer, M | 1 |
| Schauenstein, E | 1 |
| Godál, A | 1 |
| Medzihradský, J | 1 |
| Stojkovic, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 1b/2a Safety and Immunogenicity of the DNMT Inhibitor Azacitidine During Anti-Tuberculosis Therapy[NCT03941496] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2022-10-31 | Withdrawn (stopped due to The study was halted prematurely due to Bristol-Myers Squibb's (BMS) decision to withdraw support for this study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for procaine and Neoplasms
| Article | Year |
|---|---|
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydrala | 2017 |
20 other studies available for procaine and Neoplasms
| Article | Year |
|---|---|
Synthesis of dual functional procaine-derived carbon dots for bioimaging and anticancer therapy.
Topics: A549 Cells; Animals; Carbon; HaCaT Cells; Humans; Luminescence; Male; Mice; Mice, Inbred BALB C; Neo | 2020 |
Relief of pain in advanced carcinoma by prefrontal injection of procaine.
Topics: Frontal Lobe; Injections; Neoplasms; Pain; Procaine | 1953 |
[Experiences with extradural symprocaine block for pain control in advanced genital carcinoma in women].
Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, Spinal; Female; Genitalia; Genitalia, Female; Humans; | 1953 |
Complications following the use of efocaine.
Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Neoplasms; Pain; Pa | 1954 |
[Mandl technic of frontal lobe infiltration in therapy of pain, with special reference to neoplasms].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Frontal Lobe; Neoplasms; Pain Management; Procaine | 1954 |
[New technic of treatment of intractable pain; prefrontal infiltration of procaine by suborbital route].
Topics: Biophysical Phenomena; Humans; Neoplasms; Pain Management; Pain, Intractable; Procaine | 1957 |
[The surgical treatment of pain in gynecological tumors].
Topics: Anesthesia; Anesthesia, Conduction; Female; Genitalia; Genitalia, Female; Humans; Neoplasms; Pain; P | 1962 |
[INTRA-OSSEOUS ADMINISTRATION OF NOVOCAINE IN PAIN CONTROL IN MALIGNANT TUMORS AND THEIR METASTASES].
Topics: Bone and Bones; Humans; Neoplasms; Pain; Pain Management; Palliative Care; Procaine | 1963 |
ANESTHETIC MANAGEMENT OF THE PARTURIENT WITH INTRACRANIAL TUMOR.
Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, Spinal; Anesthetics; Angiography; Brain Neoplasms; | 1964 |
[TREATMENT OF RADIATION INJURY OF THE RECTUM USING THE PRESACRAL PENICILLIN-NOVOCAINE BLOCK].
Topics: Autonomic Nerve Block; Female; Humans; Neoplasms; Penicillins; Procaine; Proctitis; Radiation Injuri | 1964 |
[Vagosympathetic cervical novocaine block in esophageal and cardial cancers as a method of control of syndrome of dysphagia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Conduction; Deglutition Disorders; Esop | 1952 |
Tumour chemotherapy. II. Synthesis of nitrogen mustards related to local anaesthetics, procaine, percaine and others.
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Dermatologic Agents; Mechlorethamine; Neoplasms; | 1960 |
[Intravenous injection and infusion of novocain for the relief of pain].
Topics: Genitalia; Injections, Intravenous; Neoplasms; Pain; Procaine | 1950 |
[Clinical cases, technique and pathological changes in novocain infiltration of the frontal lobe in cancer patients with untractable pain].
Topics: Frontal Lobe; Humans; Neoplasms; Pain; Procaine | 1951 |
[Prefrontal novocain infiltration in treatment of irreducible pain in cancer].
Topics: Biophysical Phenomena; Humans; Neoplasms; Pain Management; Procaine | 1952 |
[Novocain perfusion in postoperative complications of neurosurgery].
Topics: Brain; Neoplasms; Neurosurgery; Neurosurgical Procedures; Perfusion; Plastic Surgery Procedures; Pos | 1950 |
[Prolonged peridural anesthesia in oncological patients].
Topics: Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics; Catheterization; Dura Mater; Female; Human | 1970 |
[Use of some chemical agents for protecting the skin during radiotherapy of malignant neoplasms].
Topics: Alcohols; Female; Growth Substances; Humans; Male; Neoplasms; Procaine; Radiation-Protective Agents; | 1968 |
[On the biochemistry of 4-nicotinoylaminobenzoic acid-(beta-diethylamino)-ethyl ester hydrochloride as adjuvant in the carcinoma treatment].
Topics: Animals; Benzoates; Humans; Liver; Lymphocytosis; Mice; Neoplasms; Nicotinic Acids; Oxygen Consumpti | 1969 |
An attempt to potentiate the effect of chemotherapy by means of flow increasing in blood stream.
Topics: Angiography; Animals; Blood Flow Velocity; Injections, Intra-Arterial; Leukocyte Count; Liver Regene | 1966 |