Page last updated: 2024-11-03

procaine and Necrosis

procaine has been researched along with Necrosis in 21 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" History-taking revealed a final course of mesotherapy three weeks earlier for patellar tendinitis below the left kneecap; intradermal injection of procaine and piroxicam had been unusually and intensely painful."3.79[A rare side effect of mesotherapy: Nicolau syndrome]. ( Benamara, M; Delaplace, M; Estève, E; Zaragoza, J, 2013)
"Fatty livers are particularly susceptible to mitochondrial alterations after cold preservation."1.35Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning. ( Hirner, A; Koetting, M; Minor, T; Stegemann, J, 2009)
"Necrosis was assessed by trypan blue exclusion, lactate dehydrogenase (LDH) release, and mitochondrial 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) reduction."1.32Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions. ( Abrahamse, SL; Chamuleau, RA; Hartman, RJ; van Gulik, TM; van Runnard Heimel, P, 2003)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Boening, A1
Hinke, M1
Heep, M1
Boengler, K1
Niemann, B1
Grieshaber, P1
Chen, Y1
Qin, C1
Wang, G1
Xiao, M1
Xiao, G1
Luan, Z1
Du, C1
Wang, J1
Xu, X1
Zaragoza, J1
Delaplace, M1
Benamara, M1
Estève, E1
Dmitriev, YV1
Minasyan, SM1
Vasina, LV1
Demchenko, EA1
Galagudza, MM1
Minor, T1
Stegemann, J1
Hirner, A1
Koetting, M1
Worku, D1
Laluf, S1
McGee, J1
Goswami, M1
VanMeter, K1
Slakey, DP1
Wei, L1
Wu, RB1
Yang, CM1
Zheng, SY1
Yu, XY1
Straatsburg, IH1
Abrahamse, SL2
Song, SW1
Hartman, RJ2
Van Gulik, TM2
van Runnard Heimel, P1
Chamuleau, RA1
BACZYNSKA, W1
YERASIMIDES, TG1
MARGOLIS, G1
PONTON, HJ1
BRUDER, K1
Zimmet, SE1
Goldin, VA1
Egbe, ZE1
Wilson, GJ1
Axford-Gatley, RA1
Bush, BG1
Romaschin, AD1
Mickle, DA1
Keen, TE1
Prokubovskiĭ, VI1
Filimonov, MI1
Revskoĭ, AK1
McAlister, WH1
Palmer, K1
Abe, A1

Other Studies

21 other studies available for procaine and Necrosis

ArticleYear
Cardiac surgery in acute myocardial infarction: crystalloid versus blood cardioplegia - an experimental study.
    Journal of cardiothoracic surgery, 2020, Jan-08, Volume: 15, Issue:1

    Topics: Animals; Cardioplegic Solutions; Coronary Circulation; Crystalloid Solutions; Glucose; Heart Arrest,

2020
Contribution of heparin to recovery of incarcerated intestine in a rat incarcerated hernia model.
    Hernia : the journal of hernias and abdominal wall surgery, 2019, Volume: 23, Issue:6

    Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Heparin; Hernia, Abdominal; Intestinal Obstr

2019
[A rare side effect of mesotherapy: Nicolau syndrome].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:11

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Drug Eruptions; Embolism; H

2013
Effects of Inhibitors of Necroptosis and Autophagy on Morphofunctional Characteristics of the Myocardium during Static Cold Storage of Donor Rat Heart.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:6

    Topics: Animals; Autophagy; Cardiotonic Agents; Cold Temperature; Cryopreservation; Glucose; Heart; Imidazol

2015
Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2009, Volume: 15, Issue:7

    Topics: Animals; Apoptosis; Autophagy; Cryopreservation; Fatty Liver; Glucose; Histidine; Hypothermia, Induc

2009
P-selectin expression in cold preserved kidneys in University of Wisconsin and histidine-tryptophan-ketoglutarate solutions.
    The Journal of surgical research, 2011, Volume: 169, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Cryopreservation; Down-Regulation; Glucose; Glutathione; Insulin; I

2011
NECROSIS following injection of procaine.
    Medical bulletin. United States. Army. Forces in the European Theater. Office of the Theater Chief Surgeon, 1945, Issue:30

    Topics: Anesthesia; Humans; Iatrogenic Disease; Injections; Necrosis; Postoperative Complications; Procaine

1945
Polymerised placenta haemoglobin attenuates cold ischaemia/reperfusion injury in isolated rat heart.
    Microvascular research, 2011, Volume: 82, Issue:3

    Topics: Animals; Apoptosis; Cold Ischemia; Female; Glucose; Hemoglobins; Interleukin-1beta; Mannitol; Myocar

2011
Evaluation of rat liver apoptotic and necrotic cell death after cold storage using UW, HTK, and Celsior.
    Transplantation, 2002, Aug-27, Volume: 74, Issue:4

    Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Apoptosis; Aspartate Aminotransferases; Bile;

2002
Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions.
    Cell transplantation, 2003, Volume: 12, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Apoptosis; Caspase 3; Caspases; Cell Count; Cell Culture Techniques

2003
[A case of umbilical necrosis in a premature infant weighing 1300 g and treated with novocaine and blood clot compresses].
    Pediatria polska, 1953, Volume: 28, Issue:5

    Topics: Disease; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Necrosis;

1953
PROPHYLAXIS OF EXPERIMENTAL CONTRAST MEDIUM INJURY TO THE SPINAL CORD BY VASODEPRESSOR DRUGS.
    Angiology, 1963, Volume: 14

    Topics: Acetrizoic Acid; Angiography; Blood Circulation; Blood Pressure; Blood Pressure Determination; Contr

1963
[DRUG MIX-UP IN OBERST'S ANESTHESIA].
    Medizinische Klinik, 1963, Nov-22, Volume: 58

    Topics: Anesthesia; Anesthesia, Conduction; Humans; Hypertonic Solutions; Iatrogenic Disease; Injections; Me

1963
The prevention of cutaneous necrosis following extravasation of hypertonic saline and sodium tetradecyl sulfate.
    The Journal of dermatologic surgery and oncology, 1993, Volume: 19, Issue:7

    Topics: Animals; Extravasation of Diagnostic and Therapeutic Materials; Female; Hyaluronoglucosaminidase; In

1993
[Direct infusion of drug mixture into the aorta in the treatment of necrotizing pancreatitis].
    Khirurgiia, 1991, Issue:6

    Topics: Adult; Aorta; Celiac Plexus; Drug Combinations; Humans; Injections, Intra-Arterial; Middle Aged; Nec

1991
European versus North American cardioplegia: comparison of Bretschneider's and Roe's cardioplegic solutions in a canine model of cardiopulmonary bypass.
    The Thoracic and cardiovascular surgeon, 1990, Volume: 38, Issue:1

    Topics: Animals; Buffers; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Glucose; Heart; Magnesium Ch

1990
Recent investigations on sea-wasp stingings in Australia.
    The Medical journal of Australia, 1970, Feb-07, Volume: 1, Issue:6

    Topics: Animals; Antitoxins; Atropine; Bites and Stings; Cnidaria; Epinephrine; Gluconates; Hemolysis; Hydro

1970
[Protracted administration of medical substances into the aorta in abdominal diseases].
    Khirurgiia, 1969, Volume: 45, Issue:5

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aorta; Aprotinin; Blood Transfusion; Catheterization;

1969
[Therapeutic measures in acute ischemia of the extremities].
    Voenno-meditsinskii zhurnal, 1969, Volume: 8

    Topics: Adenosine Triphosphate; Animals; Bone Marrow; Extremities; Hydrogen Peroxide; Injections; Ischemia;

1969
The histologic effects of four commonly used media for excretory urography and an attempt to modify the responses.
    Radiology, 1971, Volume: 99, Issue:3

    Topics: Animals; Diatrizoate; Edema; Hyaluronoglucosaminidase; Inflammation; Injections, Intramuscular; Inje

1971
[Case of local skin necrosis caused by procaine injection].
    Shujutsu. Operation, 1968, Volume: 22, Issue:10

    Topics: Adult; Humans; Male; Necrosis; Procaine; Skin; Skin Diseases; Thigh

1968