procaine has been researched along with Necrosis in 21 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " History-taking revealed a final course of mesotherapy three weeks earlier for patellar tendinitis below the left kneecap; intradermal injection of procaine and piroxicam had been unusually and intensely painful." | 3.79 | [A rare side effect of mesotherapy: Nicolau syndrome]. ( Benamara, M; Delaplace, M; Estève, E; Zaragoza, J, 2013) |
| "Fatty livers are particularly susceptible to mitochondrial alterations after cold preservation." | 1.35 | Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning. ( Hirner, A; Koetting, M; Minor, T; Stegemann, J, 2009) |
| "Necrosis was assessed by trypan blue exclusion, lactate dehydrogenase (LDH) release, and mitochondrial 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) reduction." | 1.32 | Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions. ( Abrahamse, SL; Chamuleau, RA; Hartman, RJ; van Gulik, TM; van Runnard Heimel, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (42.86) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Boening, A | 1 |
| Hinke, M | 1 |
| Heep, M | 1 |
| Boengler, K | 1 |
| Niemann, B | 1 |
| Grieshaber, P | 1 |
| Chen, Y | 1 |
| Qin, C | 1 |
| Wang, G | 1 |
| Xiao, M | 1 |
| Xiao, G | 1 |
| Luan, Z | 1 |
| Du, C | 1 |
| Wang, J | 1 |
| Xu, X | 1 |
| Zaragoza, J | 1 |
| Delaplace, M | 1 |
| Benamara, M | 1 |
| Estève, E | 1 |
| Dmitriev, YV | 1 |
| Minasyan, SM | 1 |
| Vasina, LV | 1 |
| Demchenko, EA | 1 |
| Galagudza, MM | 1 |
| Minor, T | 1 |
| Stegemann, J | 1 |
| Hirner, A | 1 |
| Koetting, M | 1 |
| Worku, D | 1 |
| Laluf, S | 1 |
| McGee, J | 1 |
| Goswami, M | 1 |
| VanMeter, K | 1 |
| Slakey, DP | 1 |
| Wei, L | 1 |
| Wu, RB | 1 |
| Yang, CM | 1 |
| Zheng, SY | 1 |
| Yu, XY | 1 |
| Straatsburg, IH | 1 |
| Abrahamse, SL | 2 |
| Song, SW | 1 |
| Hartman, RJ | 2 |
| Van Gulik, TM | 2 |
| van Runnard Heimel, P | 1 |
| Chamuleau, RA | 1 |
| BACZYNSKA, W | 1 |
| YERASIMIDES, TG | 1 |
| MARGOLIS, G | 1 |
| PONTON, HJ | 1 |
| BRUDER, K | 1 |
| Zimmet, SE | 1 |
| Goldin, VA | 1 |
| Egbe, ZE | 1 |
| Wilson, GJ | 1 |
| Axford-Gatley, RA | 1 |
| Bush, BG | 1 |
| Romaschin, AD | 1 |
| Mickle, DA | 1 |
| Keen, TE | 1 |
| Prokubovskiĭ, VI | 1 |
| Filimonov, MI | 1 |
| Revskoĭ, AK | 1 |
| McAlister, WH | 1 |
| Palmer, K | 1 |
| Abe, A | 1 |
21 other studies available for procaine and Necrosis
| Article | Year |
|---|---|
Cardiac surgery in acute myocardial infarction: crystalloid versus blood cardioplegia - an experimental study.
Topics: Animals; Cardioplegic Solutions; Coronary Circulation; Crystalloid Solutions; Glucose; Heart Arrest, | 2020 |
Contribution of heparin to recovery of incarcerated intestine in a rat incarcerated hernia model.
Topics: Animals; Cardiovascular Agents; Disease Models, Animal; Heparin; Hernia, Abdominal; Intestinal Obstr | 2019 |
[A rare side effect of mesotherapy: Nicolau syndrome].
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Drug Eruptions; Embolism; H | 2013 |
Effects of Inhibitors of Necroptosis and Autophagy on Morphofunctional Characteristics of the Myocardium during Static Cold Storage of Donor Rat Heart.
Topics: Animals; Autophagy; Cardiotonic Agents; Cold Temperature; Cryopreservation; Glucose; Heart; Imidazol | 2015 |
Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning.
Topics: Animals; Apoptosis; Autophagy; Cryopreservation; Fatty Liver; Glucose; Histidine; Hypothermia, Induc | 2009 |
P-selectin expression in cold preserved kidneys in University of Wisconsin and histidine-tryptophan-ketoglutarate solutions.
Topics: Adenosine; Allopurinol; Animals; Cryopreservation; Down-Regulation; Glucose; Glutathione; Insulin; I | 2011 |
NECROSIS following injection of procaine.
Topics: Anesthesia; Humans; Iatrogenic Disease; Injections; Necrosis; Postoperative Complications; Procaine | 1945 |
Polymerised placenta haemoglobin attenuates cold ischaemia/reperfusion injury in isolated rat heart.
Topics: Animals; Apoptosis; Cold Ischemia; Female; Glucose; Hemoglobins; Interleukin-1beta; Mannitol; Myocar | 2011 |
Evaluation of rat liver apoptotic and necrotic cell death after cold storage using UW, HTK, and Celsior.
Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Apoptosis; Aspartate Aminotransferases; Bile; | 2002 |
Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Caspase 3; Caspases; Cell Count; Cell Culture Techniques | 2003 |
[A case of umbilical necrosis in a premature infant weighing 1300 g and treated with novocaine and blood clot compresses].
Topics: Disease; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Necrosis; | 1953 |
PROPHYLAXIS OF EXPERIMENTAL CONTRAST MEDIUM INJURY TO THE SPINAL CORD BY VASODEPRESSOR DRUGS.
Topics: Acetrizoic Acid; Angiography; Blood Circulation; Blood Pressure; Blood Pressure Determination; Contr | 1963 |
[DRUG MIX-UP IN OBERST'S ANESTHESIA].
Topics: Anesthesia; Anesthesia, Conduction; Humans; Hypertonic Solutions; Iatrogenic Disease; Injections; Me | 1963 |
The prevention of cutaneous necrosis following extravasation of hypertonic saline and sodium tetradecyl sulfate.
Topics: Animals; Extravasation of Diagnostic and Therapeutic Materials; Female; Hyaluronoglucosaminidase; In | 1993 |
[Direct infusion of drug mixture into the aorta in the treatment of necrotizing pancreatitis].
Topics: Adult; Aorta; Celiac Plexus; Drug Combinations; Humans; Injections, Intra-Arterial; Middle Aged; Nec | 1991 |
European versus North American cardioplegia: comparison of Bretschneider's and Roe's cardioplegic solutions in a canine model of cardiopulmonary bypass.
Topics: Animals; Buffers; Cardioplegic Solutions; Cardiopulmonary Bypass; Dogs; Glucose; Heart; Magnesium Ch | 1990 |
Recent investigations on sea-wasp stingings in Australia.
Topics: Animals; Antitoxins; Atropine; Bites and Stings; Cnidaria; Epinephrine; Gluconates; Hemolysis; Hydro | 1970 |
[Protracted administration of medical substances into the aorta in abdominal diseases].
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Aorta; Aprotinin; Blood Transfusion; Catheterization; | 1969 |
[Therapeutic measures in acute ischemia of the extremities].
Topics: Adenosine Triphosphate; Animals; Bone Marrow; Extremities; Hydrogen Peroxide; Injections; Ischemia; | 1969 |
The histologic effects of four commonly used media for excretory urography and an attempt to modify the responses.
Topics: Animals; Diatrizoate; Edema; Hyaluronoglucosaminidase; Inflammation; Injections, Intramuscular; Inje | 1971 |
[Case of local skin necrosis caused by procaine injection].
Topics: Adult; Humans; Male; Necrosis; Procaine; Skin; Skin Diseases; Thigh | 1968 |