procaine has been researched along with Myotonia in 2 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myotonic discharges in rats given 20, 25-diazacholesterol hydrochloride and fibrillation discharges in denervated rat muscle both were silenced by procaine hydrochloride, tetrodotoxin or ischemia, or potassium chloride (after initial activation)." | 3.66 | The effect of pharmacologic acetylcholine receptor on fibrillation and myotonia in rat skeletal muscle. ( Bertorini, TE; Brumback, RA; Engel, WK; Oliver, KL; Trotter, JL; Zirzow, GC, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PATEISKY, K | 1 |
| Brumback, RA | 1 |
| Bertorini, TE | 1 |
| Engel, WK | 1 |
| Trotter, JL | 1 |
| Oliver, KL | 1 |
| Zirzow, GC | 1 |
2 other studies available for procaine and Myotonia
| Article | Year |
|---|---|
[Symptomatic treatment of myotonias with intravenous administration of local anesthetics (procaine & panthesin)].
Topics: Administration, Intravenous; Aminobenzoates; Anesthetics, Local; Cardiovascular Agents; Humans; Leuc | 1958 |
The effect of pharmacologic acetylcholine receptor on fibrillation and myotonia in rat skeletal muscle.
Topics: Acetylcholine; Animals; Atropine; Azacosterol; Bungarotoxins; Evoked Potentials; Ischemia; Male; Mus | 1978 |