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procaine and Muscle Relaxation

procaine has been researched along with Muscle Relaxation in 21 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" An in vitro study, using helical preparations of human umbilical arteries and veins obtained from healthy women at term pregnancy, was designed to determine: (a) whether three local anaesthetics commonly utilized in obstetric anaesthesia (bupivacaine, 2-chloroprocaine, and lignocaine) can induce contraction or relaxation of resting umbilical vessels; (b) whether these agents can induce contraction or relaxation of umbilical vessels which have been previously induced to contract by a known activator, potassium chloride (KCl); and (c) the relative potency of these agents as compared to KCl."3.67Vasoactive actions of local anaesthetics on human isolated umbilical veins and arteries. ( Altura, B; Freese, K; Halevy, S; Liu-Barnett, M; Monuszko, E, 1989)
" Acute and chronic administration of Chlo (45 mg kg-1, i."1.28Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro. ( Okwuasaba, FK; Otubu, JA; Udoh, FV, 1990)
"Procaine is a substance which is known to specifically inhibit the calcium-induced calcium release mechanism."1.27Effects of procaine on the isolated dog coronary artery. ( Imai, H; Imai, S; Nabata, H; Nakazawa, M, 1984)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199014 (66.67)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukushima, A1
Chazono, K1
Hashimoto, Y1
Iwajima, Y1
Yamamoto, S1
Maeda, Y1
Ohsawa, M1
Ono, H1
Bozkurt, TE1
Sahin-Erdemli, I1
Fedin, AN1
Kuzubova, NA1
Danilov, LN1
Lebedeva, ES1
Obara, K1
Yamada, T1
Imai, S1
Nakazawa, M1
Imai, H1
Nabata, H1
Ishi, T1
Shimo, Y1
Adeyemi, OO1
Okpo, SO1
Young-Nwafor, CC1
Nakahara, T1
Yunoki, M1
Moriuchi, H1
Sakamato, K1
Ishii, K1
Downes, H1
Loehning, RW1
Adams, PR1
Baysal, F1
Onder, S1
Ozgül, M1
Toygar, A1
Takauji, M1
Nagai, T1
Gibson, A1
James, TA1
Kitamura, K1
Suzuki, H1
Kuriyama, H1
Cowan, CL1
Cohen, RA1
Okwuasaba, FK1
Otubu, JA1
Udoh, FV1
Perkins, RS1
Paciorek, PM1
Waterfall, JF1
Monuszko, E1
Halevy, S1
Freese, K1
Liu-Barnett, M1
Altura, B1
Wilson, C1
Coldwell, MC1
Howlett, DR1
Cooper, SM1
Hamilton, TC1
Guimaraes, CR1
Rodrigues, LA1
Vettore, O1
Antonio, A1
Allen, SL1
Cortijo, J1
Foster, RW1
Morgan, GP1
Small, RC1
Weston, AH1

Other Studies

21 other studies available for procaine and Muscle Relaxation

ArticleYear
Oseltamivir produces hypothermic and neuromuscular effects by inhibition of nicotinic acetylcholine receptor functions: comparison to procaine and bupropion.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Animals; Bradycardia; Bupropion; Drug Synergism; Fever; Hypotension; Male; Mice; Muscle Relaxation;

2015
Evaluation of the rat bladder-derived relaxant factor by coaxial bioassay system.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Acetylcholine; Animals; Biological Assay; Biological Factors; Bupivacaine; Dose-Response Relationshi

2004
[Functional disturbances in the nervous structures of the respiratory tract in rats following nitrogen dioxide inhalation].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:9

    Topics: Anesthetics, Local; Animals; Bronchi; Glucocorticoids; In Vitro Techniques; Male; Muscle Contraction

2007
Some properties of chemically skinned single smooth muscle cells.
    The Japanese journal of physiology, 1984, Volume: 34, Issue:6

    Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Cecum; Guinea Pigs; Intracellular Membranes; Mus

1984
Effects of procaine on the isolated dog coronary artery.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:1

    Topics: Animals; Caffeine; Calcium; Coronary Vessels; Dogs; Female; In Vitro Techniques; Lanthanum; Male; Mu

1984
Potassium-induced relaxation of the rat anococcygeus muscle.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 243, Issue:1

    Topics: Animals; Barium; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; O

1980
The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles.
    Journal of ethnopharmacology, 1999, Dec-15, Volume: 68, Issue:1-3

    Topics: Animals; Colon; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Intestines; Isopro

1999
Lidocaine potentiates the relaxant effects of cAMP-elevating agents in bovine tracheal smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Albuterol; Anesthetics, Local; Animals; Bupivacaine; Cattle; Colforsin;

2000
Local anesthetic contracture and relaxation of airway smooth muscle.
    Anesthesiology, 1977, Volume: 47, Issue:5

    Topics: Aminobenzoates; Anesthetics, Local; Animals; Bronchodilator Agents; Bupivacaine; Carbachol; Guinea P

1977
Voltage jump analysis of procaine action at frog end-plate.
    The Journal of physiology, 1977, Volume: 268, Issue:2

    Topics: Animals; Anura; Choline; Electric Conductivity; In Vitro Techniques; Kinetics; Membrane Potentials;

1977
The effect of potassium on frog stomach muscle.
    British journal of pharmacology, 1979, Volume: 66, Issue:2

    Topics: Animals; Anura; Biological Transport, Active; Muscle Contraction; Muscle Relaxation; Ouabain; Papave

1979
Effect of dantrolene sodium on the inactivation of excitation-contraction coupling in frog skeletal muscle.
    The Japanese journal of physiology, 1977, Volume: 27, Issue:6

    Topics: Animals; Anura; Calcium; Dantrolene; Hydantoins; In Vitro Techniques; Muscle Contraction; Muscle Rel

1977
The nature of potassium chloride-induced relaxations of the rat anococcygeus muscle.
    British journal of pharmacology, 1977, Volume: 60, Issue:1

    Topics: Animals; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Mus

1977
Prostaglandin action on the main pulmonary artery and portal vein of the rabbit.
    The Japanese journal of physiology, 1976, Volume: 26, Issue:6

    Topics: Animals; Caffeine; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contr

1976
Different mechanisms of relaxation of pig coronary artery to bradykinin and cromakalim are distinguished by potassium channel blockers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Benzopyrans; Bradykinin; Calcium; Coronary Vessels

1992
Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Caffeine; Calcium; Chloroquine; Dantrolene; Diaphragm; Electric Stimulation; Female; In Vit

1990
Glibenclamide and procaine, but not apamin, inhibit the relaxant responses to Ro 31-6930 in guinea-pig taenia caeci.
    British journal of pharmacology, 1989, Volume: 98 Suppl

    Topics: Animals; Apamin; Bee Venoms; Benzopyrans; Cecum; Colon; Female; Glyburide; Guinea Pigs; In Vitro Tec

1989
Vasoactive actions of local anaesthetics on human isolated umbilical veins and arteries.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Anesthetics, Local; Bupivacaine; Female; Humans; In Vitro Techniques; Lidocaine; Muscle Contraction;

1989
Comparative effects of K+ channel blockade on the vasorelaxant activity of cromakalim, pinacidil and nicorandil.
    European journal of pharmacology, 1988, Aug-02, Volume: 152, Issue:3

    Topics: 4-Aminopyridine; Aminopyridines; Animals; Benzopyrans; Cardiovascular Agents; Cromakalim; Guanidines

1988
The relaxing response of the isolated rat duodenum to nicotine.
    General pharmacology, 1988, Volume: 19, Issue:5

    Topics: Adenosine Triphosphate; Animals; Atropine; Autonomic Nervous System; Dimethylphenylpiperazinium Iodi

1988
Mechanical and electrical aspects of the relaxant action of aminophylline in guinea-pig isolated trachealis.
    British journal of pharmacology, 1986, Volume: 88, Issue:2

    Topics: Acetylcholine; Aminophylline; Animals; Cell Membrane; Female; Guinea Pigs; Histamine; In Vitro Techn

1986