procaine has been researched along with Malignant Melanoma in 5 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An established human melanoma cell line (SHG) derived from malignant ascites was used to evaluate the growth-inhibitory effects of local anesthetics (procaine and lidocaine) as well as of doxorubicin at incubation temperatures of 37." | 3.66 | Doxorubicin cytotoxicity enhanced by local anesthetics in a human melanoma cell line. ( Block, JB; Chlebowski, RT; Cundiff, D; Dietrich, MF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Maksoud, MS | 1 |
| El-Gamal, MI | 1 |
| Lee, BS | 1 |
| Gamal El-Din, MM | 1 |
| Jeon, HR | 1 |
| Kwon, D | 1 |
| Ammar, UM | 1 |
| Mersal, KI | 1 |
| Ali, EMH | 1 |
| Lee, KT | 1 |
| Yoo, KH | 1 |
| Han, DK | 1 |
| Lee, JK | 1 |
| Kim, G | 1 |
| Choi, HS | 1 |
| Kwon, YJ | 1 |
| Lee, KH | 1 |
| Oh, CH | 1 |
| VENKEI, T | 1 |
| Chlebowski, RT | 1 |
| Block, JB | 1 |
| Cundiff, D | 1 |
| Dietrich, MF | 1 |
| Zhu, WG | 1 |
| Roberts, ZV | 1 |
| Dynlacht, JR | 1 |
| Borden, H | 1 |
| Hummer, GJ | 1 |
| Landon, CW | 1 |
| Paris, J | 1 |
5 other studies available for procaine and Malignant Melanoma
| Article | Year |
|---|---|
Discovery of New Imidazo[2,1-
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Drug Scr | 2021 |
[Thermoelectrometric examinations in pathologic skin changes. II].
Topics: Autonomic Nerve Block; Body Temperature; Hemangiosarcoma; Histamine H1 Antagonists; Humans; Keratoac | 1963 |
Doxorubicin cytotoxicity enhanced by local anesthetics in a human melanoma cell line.
Topics: Cell Line; Cell Survival; Doxorubicin; Drug Synergism; Humans; Lidocaine; Melanoma; Procaine; Temper | 1982 |
Heat-induced modulation of lamin B content in two different cell lines.
Topics: Anesthetics, Local; Blotting, Western; Cell Survival; Glycerol; Heat-Shock Response; HeLa Cells; Hum | 1999 |
The use of procaine in acquired malignant hyperthermia in a patient with malignant melanoma metastatic to the parathyroid gland: a case report.
Topics: Humans; Male; Malignant Hyperthermia; Melanoma; Middle Aged; Neoplasm Metastasis; Parathyroid Glands | 1976 |