Page last updated: 2024-11-03

procaine and Itching

procaine has been researched along with Itching in 28 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Research Excerpts

ExcerptRelevanceReference
"Histamine 10 microl was injected into each bleb, and the resulting magnitude of itch estimated."2.69Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia. ( Atanassoff, PG; Brull, SJ; Greenquist, K; Lamotte, RH; Silverman, DG; Zhang, J, 1999)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's1 (3.57)18.2507
2000's2 (7.14)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Gokdemir, G1
Küçükünal, A1
Sakiz, D1
BEINHAUER, LG3
O'BRIEN, JR1
BINDA, B1
PALMERIO, C1
ULBRICH, AP1
KOPRINCE, D1
TEVEROVSKII, MI1
PARISH, FA1
GOLOTA, VIa1
BERLIN, C2
MEIROVITZ, K1
TADJER, A1
BARTUNKOVA, Z1
VESELY, K1
MEYROVITZ, C1
TAGER, A1
SANDERINK, JF1
KACHKOVSKII, MA1
Vath, JS1
Kopacz, DJ1
PICKETT, D1
LUDDECKE, H1
THOMAS, GJ1
PERRIN, SR2
MILLAN GUTIERREZ, J1
RUILOBA BENITEZ, J1
TRAPL, J1
JIRASEK, L1
Atanassoff, PG1
Brull, SJ1
Zhang, J1
Greenquist, K1
Silverman, DG1
Lamotte, RH1
Tagliavini, R1
Lucchelli, PE1
Colombi, A1
de Moragas, JM1
Giménez-Camarasa, JM1
Noguera, J1
Kolokolova, NV1
Belov, SD1
Dmitriev, GA1
Lakhtikova, MD1
Popov, IS1
Serbin, VI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Spinal Anesthesia With Bupivacaine or 2-chloroprocaine for Outpatient Elective Surgery: a Prospective, Randomized, Double-blind Comparison.[NCT00845962]106 participants (Actual)Interventional2009-02-28Completed
Comparison of 1% Chloroprocaine vs. Hyperbaric Bupivacaine Spinals in Patients Undergoing Hemorrhoidectomies in an Ambulatory Surgery Center: A Double-Blind Randomized Controlled Pilot Trial.[NCT03324984]Phase 2110 participants (Actual)Interventional2019-09-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for procaine and Itching

ArticleYear
Spinal 2-chloroprocaine: the effect of added fentanyl.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Local

2004
Spinal 2-chloroprocaine: the effect of added fentanyl.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Local

2004
Spinal 2-chloroprocaine: the effect of added fentanyl.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Local

2004
Spinal 2-chloroprocaine: the effect of added fentanyl.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anesthetics, Local

2004
Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia.
    Somatosensory & motor research, 1999, Volume: 16, Issue:4

    Topics: Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Forearm; Histamine; Humans; Hy

1999

Other Studies

26 other studies available for procaine and Itching

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
CONTROL of pruritus with intravenous procaine.
    What's new, 1952, Volume: 168

    Topics: Procaine; Pruritus

1952
Cutaneous granulomatous reaction from mesotherapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:2

    Topics: Adult; Body Modification, Non-Therapeutic; Dapsone; Female; Granuloma; Humans; Injections, Subcutane

2009
Use of oral procaine in control of pruritus.
    A.M.A. archives of dermatology and syphilology, 1954, Volume: 69, Issue:2

    Topics: Procaine; Pruritus

1954
Efocaine in pruritus ani.
    The Journal of the Medical Society of New Jersey, 1954, Volume: 51, Issue:7

    Topics: Aminobenzoates; Anal Canal; Anus Diseases; Humans; Procaine; Pruritus; Pruritus Ani

1954
[Novocaine and autosanguineous infiltrations in anal pruritus; surgery of severe cases of essential anal pruritus].
    Minerva anestesiologica, 1954, Volume: 20, Issue:3

    Topics: Anal Canal; Anus Diseases; Procaine; Pruritus

1954
[Association of an anesthetic of retarded action and of an antihistaminic in local therapy of essential anal pruritus].
    Gazzetta medica italiana, 1954, Volume: 113, Issue:4

    Topics: Anal Canal; Anesthetics; Anti-Allergic Agents; Anus Diseases; Histamine H1 Antagonists; Procaine; Pr

1954
The use of oral procaine for pruritus.
    The Journal of the American Osteopathic Association, 1954, Volume: 53, Issue:12

    Topics: Procaine; Pruritus

1954
[Treatment of severe forms of pruritus of external female genitalia].
    Sovetskaia meditsina, 1957, Volume: 21, Issue:2

    Topics: Disease; Female; Genitalia, Female; Humans; Pelvis; Perineum; Procaine; Pruritus; Vulva; Vulvar Dise

1957
Pruritus.
    Medical times, 1958, Volume: 86, Issue:9

    Topics: Ascorbic Acid; Procaine; Pruritus; Vitamins

1958
[Pruritus of the external genitalia and its treatment].
    Pediatriia akusherstvo i ginekologiia, 1962, Volume: 5

    Topics: Autonomic Nerve Block; Female; Gynecology; Humans; Perineum; Procaine; Pruritus; Vulva

1962
[Procaine for control of pruritus].
    Harefuah, 1954, Dec-15, Volume: 47, Issue:12

    Topics: Herpes Zoster; Humans; Procaine; Pruritus

1954
[Therapy of pruritus vulvae with novocaine block].
    Ceskoslovenska gynekologie, 1955, Volume: 20, Issue:1

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Disease; Female; Humans; Pain Management; Procaine;

1955
Procaine in control of pruritus.
    Dermatologica, 1955, Volume: 110, Issue:2

    Topics: Procaine; Pruritus

1955
[Treatment of pruritus anogenitalis by means of a local anesthetic with prolonged action (efocaine)].
    Nederlands tijdschrift voor geneeskunde, 1955, Apr-30, Volume: 99, Issue:18

    Topics: Aminobenzoates; Anal Canal; Anesthetics, Local; Anus Diseases; Disease; Genitalia; Procaine; Pruritu

1955
[On the treatment of pruritic dermatoses by electrophoresis of novocain].
    Vestnik dermatologii i venerologii, 1962, Volume: 36

    Topics: Electrophoresis; Humans; Procaine; Pruritus; Skin Diseases

1962
Intravenous procaine hydrochloride for treatment of pruritus in dogs.
    Veterinary medicine, 1951, Volume: 46, Issue:7

    Topics: Animals; Dogs; Procaine; Pruritus

1951
Oral administration of procaine with ascorbic acid, with special reference to the therapy of pruritus.
    A.M.A. archives of dermatology and syphilology, 1951, Volume: 64, Issue:1

    Topics: Administration, Oral; Ascorbic Acid; Hypersensitivity; Immune System Diseases; Procaine; Pruritus; V

1951
Intravenous use of procaine hydrochloride in control of pruritus.
    A.M.A. archives of dermatology and syphilology, 1952, Volume: 65, Issue:1

    Topics: Injections, Intravenous; Procaine; Pruritus

1952
[Preliminary note on the use of procaine in the treatment of pruritus].
    La Prensa medica mexicana, 1951, Volume: 16, Issue:6

    Topics: Procaine; Pruritus

1951
Intravenous injection of procaine in treatment of pruritus ani.
    Pennsylvania medical journal (1928), 1952, Volume: 55, Issue:2

    Topics: Anal Canal; Anus Diseases; Injections, Intravenous; Procaine; Pruritus; Pruritus Ani

1952
Intravenous novocaine in pruritic dermatoses.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:2

    Topics: Dermatitis; Humans; Procaine; Pruritus; Skin Diseases

1950
[Analgesic effect of a corticosteroid for local use].
    Minerva medica, 1971, Mar-31, Volume: 62, Issue:26

    Topics: Antipyrine; Burns; Clioquinol; Ear Diseases; Female; Flumethasone; Fluorine; Glucocorticoids; Glycol

1971
Localized heat urticaria.
    Archives of dermatology, 1973, Volume: 108, Issue:5

    Topics: Adult; Atropine; Epinephrine; Female; Forearm; Histamine; Hot Temperature; Humans; Immunization, Pas

1973
[Treating some pruritic dermatoses and keloid scars with a novocaine block with lidase].
    Sovetskaia meditsina, 1971, Volume: 34, Issue:12

    Topics: Adolescent; Adult; Cicatrix; Female; Humans; Hyaluronoglucosaminidase; Keloid; Male; Middle Aged; Pr

1971
[The treatment of genital and anal pruritus].
    Vrachebnoe delo, 1968, Volume: 4

    Topics: Adult; Anesthesia, Spinal; Female; Genital Diseases, Male; Humans; Male; Middle Aged; Procaine; Prur

1968