procaine has been researched along with Intraocular Pressure in 21 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A prospective study on 18 volunteers and 10 glaucoma patients was set up to find out whether oxybuprocaine eyedrops or repeated applanation tonometry could have anything to do with this." | 7.67 | The influence of oxybuprocaine (Novesine) on the intraocular pressure. ( de Heer, LJ; Leys, M; van Rij, G, 1986) |
| "We studied, using anesthetized albino rabbits, whether polymodal receptors are responsible for rise in the intraocular pressure (IOP) caused by algesic substances, and also whether substance P (SP) is involved in this phenomenon." | 3.68 | Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation. ( Awaya, S; Kumazawa, T; Mizumura, K; Yokoyama, K, 1990) |
| " A prospective study on 18 volunteers and 10 glaucoma patients was set up to find out whether oxybuprocaine eyedrops or repeated applanation tonometry could have anything to do with this." | 3.67 | The influence of oxybuprocaine (Novesine) on the intraocular pressure. ( de Heer, LJ; Leys, M; van Rij, G, 1986) |
| "In aging eyes phenylephrine drops have no significant effect on the depth of the anterior chamber, whereas pilocarpine drops produce a significant shallowing." | 3.66 | Acute shallowing of the anterior chamber. ( Mapstone, R, 1981) |
| " Acepromazine, ketamine, xylazine, droperidol-fentamyl, and combinations of these drugs were evaluated for effects on blood pressure, intraocular pressure, and restraint of the dog for 4 minutes of Schiotz tonography of each eye." | 3.65 | Tonography in the normal and glaucomatous beagle. ( Gelatt, KN; Gum, GG; Gwin, RM; Peiffer, RL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ehongo, A | 1 |
| De Maertelaer, V | 1 |
| Pourjavan, S | 1 |
| El Rami, H | 1 |
| Fadlallah, A | 1 |
| Fahd, D | 1 |
| Fahed, S | 1 |
| Sanchis-Gimeno, JA | 1 |
| Palanca-Sanfrancisco, JM | 1 |
| García-Lázaro, S | 1 |
| Madrid-Costa, D | 1 |
| Cerviño, A | 1 |
| Jóhannesson, G | 1 |
| Hallberg, P | 1 |
| Eklund, A | 1 |
| Behndig, A | 1 |
| Lindén, C | 1 |
| Sauder, G | 1 |
| Jonas, JB | 1 |
| VESPER, G | 1 |
| UGLOVA, TG | 1 |
| MIKLOS, A | 1 |
| HALMAI, O | 1 |
| REHAK, S | 1 |
| VRANA, M | 1 |
| Endo, Y | 1 |
| Innemee, HC | 1 |
| de Jonge, A | 1 |
| van Meel, JC | 1 |
| Timmermans, PB | 1 |
| van Zwieten, PA | 1 |
| Haddad, R | 1 |
| Grabner, G | 1 |
| Strasser, G | 1 |
| Witzmann, K | 1 |
| Mapstone, R | 1 |
| Jose, JG | 1 |
| Basta, M | 1 |
| Cramer, KJ | 1 |
| Fain, M | 1 |
| Turetsky, D | 1 |
| Pianka, P | 1 |
| Weintraub-Padova, H | 1 |
| Lazar, M | 1 |
| Geyer, O | 1 |
| Gelatt, KN | 1 |
| Gwin, RM | 1 |
| Peiffer, RL | 1 |
| Gum, GG | 1 |
| Yokoyama, K | 1 |
| Awaya, S | 1 |
| Mizumura, K | 1 |
| Kumazawa, T | 1 |
| Leys, M | 1 |
| van Rij, G | 1 |
| de Heer, LJ | 1 |
| Judit, BS | 1 |
| Hara, T | 1 |
| Suda, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Clonidine Added to Lidocaine in Sub-Tenon's and Peribulbar Anesthesia: Assessments of Intraocular Pressure (IOP), Ocular Perfusion Pressure (OPP) and Ocular Pulse Amplitude (OPA)[NCT02733757] | Phase 2 | 80 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02733757)
Timeframe: Within 10 minutes before the surgery procedure
| Intervention | mmHg (Mean) |
|---|---|
| Sub-Tenon's Group Control | 18 |
| Sub-Tenon's Group Clonidine | 16 |
| Peribulbar Group Control | 19 |
| Peribulbar Group Clonidine | 16 |
1 review available for procaine and Intraocular Pressure
| Article | Year |
|---|---|
[Our investigations on glaucoma studies at the department of ophthalmology, Kumamoto University].
Topics: Acetazolamide; Animals; Aqueous Humor; Arteries; Blood Pressure; Ciliary Body; Epinephrine; Follow-U | 1969 |
2 trials available for procaine and Intraocular Pressure
| Article | Year |
|---|---|
Topical anesthesia for penetrating trabeculectomy.
Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Female; Glaucoma; Human | 2002 |
Effect of sub-Tenon's and peribulbar anesthesia on intraocular pressure and ocular pulse amplitude.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Fascia; Female; Huma | 2001 |
18 other studies available for procaine and Intraocular Pressure
| Article | Year |
|---|---|
Effect of topical corneal anaesthesia on ocular response analyzer parameters: pilot study.
Topics: Adult; Anesthetics, Local; Cornea; Cross-Sectional Studies; Humans; Intraocular Pressure; Middle Age | 2009 |
Patient-perceived pain during laser in situ keratomileusis: comparison of fellow eyes.
Topics: Adult; Blood Pressure; Diazepam; Eye Pain; Female; Humans; Hypnotics and Sedatives; Intraocular Pres | 2012 |
The effect of anesthetic eye drop instillation on the distribution of corneal thickness.
Topics: Administration, Topical; Anesthetics, Local; Cornea; Corneal Topography; Emmetropia; Female; Humans; | 2013 |
Effects of topical anaesthetics and repeated tonometry on intraocular pressure.
Topics: Adult; Anesthetics, Local; Female; Healthy Volunteers; Humans; Intraocular Pressure; Male; Middle Ag | 2014 |
[On the intraocular pressure lowering effect of 2-chlorprocaine-D (Leuna)].
Topics: Eye Diseases; Intraocular Pressure; Procaine; Tonometry, Ocular | 1961 |
[RETROBULBAR INJECTION OF ALCOHOL IN THE TREATMENT OF ABSOLUTE PAINFUL GLAUCOMA].
Topics: Alcohols; Ciliary Body; Ganglia; Glaucoma; Humans; Injections; Intraocular Pressure; Pain; Procaine; | 1964 |
[DOES RETROBULBAR INJECTION OR DIGITAL COMPRESSION DIMINISH THE INCIDENCE OF VITREOUS BODY LOSS IN CATARACT OPERATIONS?].
Topics: Cataract; Cataract Extraction; Eye Diseases; Humans; Incidence; Injections; Intraocular Pressure; Po | 1964 |
Attempt at blocking oculo-ocular reactions of intraocular pressure in experimental animals.
Topics: Anesthesia; Anesthesia, Conduction; Animals; Eye; Eye Diseases; Intraocular Pressure; Procaine; Tono | 1961 |
[Fluctuation of intraocular pressure by stellate ganglion block].
Topics: Autonomic Nerve Block; Humans; Intraocular Pressure; Procaine; Stellate Ganglion | 1966 |
Differential effects of selective alpha 1- and alpha 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Female; Intra | 1982 |
[The effect of neural mediation on the immediate rise in intraocular pressure in glaucomatous eyes after cyclocryotherapy (author's transl)].
Topics: Ciliary Body; Cryosurgery; Glaucoma; Humans; Intraocular Pressure; Nerve Block; Procaine; Synaptic T | 1981 |
Acute shallowing of the anterior chamber.
Topics: Acetazolamide; Aged; Aging; Anterior Chamber; Glaucoma; Humans; Intraocular Pressure; Iris; Middle A | 1981 |
Lack of effects of anesthetic on measurement of intraocular pressure by Goldmann tonometry.
Topics: Administration, Topical; Anesthetics, Local; Humans; Intraocular Pressure; Procaine; Propoxycaine; T | 1983 |
Tonography in the normal and glaucomatous beagle.
Topics: Acepromazine; Animals; Aqueous Humor; Atropine; Blood Pressure; Dog Diseases; Dogs; Droperidol; Drug | 1977 |
Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation.
Topics: Animals; Anterior Chamber; Aspirin; Bradykinin; Female; Glucose; Intraocular Pressure; Male; Neuriti | 1990 |
The influence of oxybuprocaine (Novesine) on the intraocular pressure.
Topics: Adult; Female; Glaucoma; Humans; Intraocular Pressure; Male; Procaine; Tonometry, Ocular | 1986 |
[Iatrogenic lesion in ophthalmologic anesthesia].
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blin | 1972 |
[Intra capsular lens extraction. Operative technique and management of the patients].
Topics: Aged; Anaphylaxis; Cataract Extraction; Female; Humans; Intraocular Pressure; Lens, Crystalline; Met | 1973 |