Page last updated: 2024-11-03

procaine and Hypothermia

procaine has been researched along with Hypothermia in 20 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."7.91Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."3.91Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199014 (70.00)18.7374
1990's3 (15.00)18.2507
2000's1 (5.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schaefer, M1
Gross, W1
Gebhard, MM1
Li, WC1
Gao, H1
Gao, J1
Wang, ZJ1
ALLEN, FM1
FILIPPI, P2
SACCON, C2
MIGLIORINI, G1
SZEKERES, L1
LENARD, G1
PAVAN, WL1
GRIESEMER, RD1
THOMAS, RW1
BRASLAVSKAIA, BF1
OBAL, F1
KELEMEN, A1
FESZT, G1
FALL, S1
DUBROWSKI, J1
PANASEWICZ, J1
MARCZAK, K1
Vekemans, K1
Liu, Q1
Brassil, J1
Komuta, M1
Pirenne, J1
Monbaliu, D1
Kim-Lee, MH1
Stokes, BT1
McDonald, JS1
Gerber, SH1
Heyer, C1
Krüger, C1
Hagl, S1
Kübler, W1
Haass, M1
Hynson, JM1
Sessler, DI1
Glosten, B1
McGuire, J1
Dionigi, R1
Alexander, JW1
Collins, GM1
Hartley, LC1
Clunie, GJ1
Hübner, G1
Kalser, SC2
Kelly, MP1
Forbes, EB1
Randolph, MM2
Kelvington, EJ1
Kunig, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pre Warming Protocol Implementation Strategy in the Operation Room Routine[NCT05573152]300 participants (Actual)Interventional2015-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for procaine and Hypothermia

ArticleYear
[CARDIAC RESUSCITATION. CURRENT STATUS].
    Hospital (Rio de Janeiro, Brazil), 1963, Volume: 64

    Topics: Electric Stimulation Therapy; Epinephrine; Heart Arrest; Heart Massage; Humans; Hypothermia; Hypothe

1963
Electron microscopic investigation of cardioplegia. Electron microscopy of various forms of cardiac arrest in correlation with myocardial function.
    Methods and achievements in experimental pathology, 1971, Volume: 5

    Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Citrates; Coronary Disease; Disease Models, Animal; D

1971

Other Studies

18 other studies available for procaine and Hypothermia

ArticleYear
Hearts during ischemia with or without HTK-protection analysed by dielectric spectroscopy.
    Physiological measurement, 2018, 02-26, Volume: 39, Issue:2

    Topics: Adenosine Triphosphate; Animals; Dielectric Spectroscopy; Dogs; Gap Junctions; Glucose; Heart; Hepta

2018
Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368.
    BMC anesthesiology, 2019, 01-08, Volume: 19, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Gap Junc

2019
Discrepant animal and clinical observations on hypothermia and procaine.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Anesthetics, Local; Animals; Cold Temperature; Humans; Hypothermia; Procaine

1948
[Novocaine poisoning induced by endocarotid administration in animals under hypothermia].
    Minerva anestesiologica, 1955, Volume: 21, Issue:7

    Topics: Body Temperature; Hypothermia; Poisoning; Procaine

1955
[An experimental study of the behavior of the heart during novocaine poisoning in animals in hypothermia].
    Minerva anestesiologica, 1955, Volume: 21, Issue:9

    Topics: Animals; Body Temperature; Heart; Hypothermia; Poisoning; Procaine

1955
[Change in the fibrillation threshold of auricular and ventricular musculature of isolated mammalian heart after cooling and after administration of various pharmacological agents].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1960, Volume: 238

    Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Con

1960
LIPOGENESIS IN HUMAN SKIN. II. THE EFFECT OF PHYSICAL AND CHEMICAL FACTORS ON IN VITRO LIPOGENESIS FROM ACETATE.
    The Journal of investigative dermatology, 1963, Volume: 41

    Topics: Acetates; Adipogenesis; Anesthesia; Anesthesia, Local; Biopsy; Chromatography; Fatty Acids; Glucose;

1963
[THERMOREGULATORY REACTIONS AND THEIR CHANGES UNDER THE INFLUENCE OF PREOPERATIVE CARE IN THYROTOXICOSIS PATIENTS].
    Sovetskaia meditsina, 1964, Volume: 27

    Topics: Body Temperature Regulation; Drug Therapy; Glucose; Humans; Hyperthyroidism; Hypothermia; Preoperati

1964
[The role of the nervous system in hypothermic effect of ergot alakaloids and novocaine].
    Acta physiologica Academiae Scientiarum Hungaricae, 1954, Volume: Suppl. 6

    Topics: Body Temperature; Ergot Alkaloids; Hypothermia; Nervous System; Procaine

1954
[Effect of hypothermia, ether anesthesia, and intravenous novocaine on reactions of the vasoreceptors].
    Acta physiologica Polonica, 1954, Volume: 5, Issue:4

    Topics: Anesthesia; Anesthetics; Blood Vessels; Cardiovascular Physiological Phenomena; Cold Temperature; Et

1954
Influence of flow and addition of oxygen during porcine liver hypothermic machine perfusion.
    Transplantation proceedings, 2007, Volume: 39, Issue:8

    Topics: Adenosine Triphosphate; Animals; Glucose; Hepatic Artery; Hypothermia; Liver; Mannitol; Models, Anim

2007
Procaine, lidocaine, and hypothermia inhibit calcium paradox in glial cells.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:4

    Topics: Analysis of Variance; Calcium; Carrier Proteins; Humans; Hypothermia; Lidocaine; Neuroglia; Procaine

1994
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fev

1999
Thermal balance and tremor patterns during epidural anesthesia.
    Anesthesiology, 1991, Volume: 74, Issue:4

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Electromyography; Fema

1991
Prevention of outflow block of the canine liver during transplantation.
    Transplantation, 1970, Volume: 9, Issue:1

    Topics: Animals; Bicarbonates; Diphenhydramine; Dogs; Heparin; Hydrocortisone; Hypothermia; Lactates; Liver

1970
Kidney preservation for transportation. 5. Comparison of perfusates for hypothermic storage.
    The Medical journal of Australia, 1971, May-29, Volume: 1, Issue:22

    Topics: Animals; Dextrans; Dogs; Heparin; Hypothermia; Kidney Transplantation; Perfusion; Plasma; Plasma Sub

1971
Drug metabolism in hypothermia. Uptake, metabolism and biliary excretion of pentobarbital-2-C14 by the isolated, perfused rat liver in hypothermia and euthermia.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:1

    Topics: Animals; Atropine; Bile; Carbon Isotopes; Hypothermia; Liver; Male; Pentobarbital; Perfusion; Procai

1969
Drug metabolism in hypothermia. Uptake, metabolism and excretion of C14-procaine by the isolated, perfused rat liver.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 164, Issue:2

    Topics: Animals; Atropine; Bile; Carbon Isotopes; Hypothermia; Liver; Perfusion; Procaine; Rats; Sulfanilami

1968