procaine and Fetal Death studies

procaine and Fetal Death

procaine has been researched along with Fetal Death in 6 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.

Research Excerpts

Excerpt	Relevance	Reference
"Embryo-lethal and teratogenic effects caused by the cisplatin-procaine complex cis-diaminechloro-[2-(diethylamino) ethyl 4-amino-benzoate, N(4)]-chlorideplatinum(II) monohydrochloride monohydrate (DPR) were examined in CD-1 mice after a single administration of 7, 14, 21 or 28 mg/kg, injected on day 6, 9, 13 or 16 of pregnancy."	3.72	Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice. ( Lapide, M; Mandys, V; Ognio, E; Ottone, M; Parodi, B; Peterka, M; Viale, M, 2003)

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (83.33)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (16.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

5 (83.33)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (16.67)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Ognio, E	1
Lapide, M	1
Ottone, M	1
Mandys, V	1
Peterka, M	1
Parodi, B	1
Viale, M	1
Ranney, B	2
Stanage, WF	2
Arnold, NI	1
Schubert, J	1
Shnider, SM	1

Studies

Ognio, E

Lapide, M

Ottone, M

Mandys, V

Peterka, M

Parodi, B

Viale, M

Ranney, B

Stanage, WF

Arnold, NI

Schubert, J

Shnider, SM

Clinical Trials (1)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery[NCT03760718]	Early Phase 1	15 participants (Anticipated)	Interventional	2019-09-30	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery[NCT03760718]

Early Phase 1

15 participants (Anticipated)

Interventional

2019-09-30

Active, not recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for procaine and Fetal Death

Article	Year
Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice. Archives of toxicology, 2003, Volume: 77, Issue:10 Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Bone and Bones; Cisplatin; Dose-Respons	2003
II. The advantages of local anesthesia for cesarean section (prenatal, neonatal, and developmental comparisons). South Dakota journal of medicine, 1975, Volume: 28, Issue:2 Topics: Anesthesia, Conduction; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Birth Weight	1975
Advantages of local anesthesia for cesarean section. Obstetrics and gynecology, 1975, Volume: 45, Issue:2 Topics: Anesthesia, Local; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Fetal Death; Humans;	1975
Paracervical block with low doses of chloroprocaine. Fetal and maternal effects. JAMA, 1975, Jan-06, Volume: 231, Issue:1 Topics: Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Evaluation Studies as Topic; Female; Fetal Death	1975
[Animal experimental studies on preventive drug therapy of congenital cleft formation. I. Radiation-induced cleft palate in mice]. Deutsche Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt fur die gesamte Zahn-, Mund-, und Kieferheilkunde, 1972, Volume: 59, Issue:7 Topics: Animals; Cleft Palate; Female; Fetal Death; Fetus; Gestational Age; Hypoxia; Injections, Intraperito	1972
New and interesting aspects of obstetric conduction anesthesia. A. Placental transfer of local anesthetics. Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 25 Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Animals; Fe	1966

Article

Year

Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice.

Archives of toxicology, 2003, Volume: 77, Issue:10

Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Bone and Bones; Cisplatin; Dose-Respons

2003

II. The advantages of local anesthesia for cesarean section (prenatal, neonatal, and developmental comparisons).

South Dakota journal of medicine, 1975, Volume: 28, Issue:2

Topics: Anesthesia, Conduction; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Birth Weight

1975

Advantages of local anesthesia for cesarean section.

Obstetrics and gynecology, 1975, Volume: 45, Issue:2

Topics: Anesthesia, Local; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Fetal Death; Humans;

1975

Paracervical block with low doses of chloroprocaine. Fetal and maternal effects.

JAMA, 1975, Jan-06, Volume: 231, Issue:1

Topics: Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Evaluation Studies as Topic; Female; Fetal Death

1975

[Animal experimental studies on preventive drug therapy of congenital cleft formation. I. Radiation-induced cleft palate in mice].

Deutsche Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt fur die gesamte Zahn-, Mund-, und Kieferheilkunde, 1972, Volume: 59, Issue:7

Topics: Animals; Cleft Palate; Female; Fetal Death; Fetus; Gestational Age; Hypoxia; Injections, Intraperito

1972

New and interesting aspects of obstetric conduction anesthesia. A. Placental transfer of local anesthetics.

Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 25

Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Animals; Fe

1966