Page last updated: 2024-11-03

procaine and Fetal Death

procaine has been researched along with Fetal Death in 6 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.

Research Excerpts

ExcerptRelevanceReference
"Embryo-lethal and teratogenic effects caused by the cisplatin-procaine complex cis-diaminechloro-[2-(diethylamino) ethyl 4-amino-benzoate, N(4)]-chlorideplatinum(II) monohydrochloride monohydrate (DPR) were examined in CD-1 mice after a single administration of 7, 14, 21 or 28 mg/kg, injected on day 6, 9, 13 or 16 of pregnancy."3.72Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice. ( Lapide, M; Mandys, V; Ognio, E; Ottone, M; Parodi, B; Peterka, M; Viale, M, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ognio, E1
Lapide, M1
Ottone, M1
Mandys, V1
Peterka, M1
Parodi, B1
Viale, M1
Ranney, B2
Stanage, WF2
Arnold, NI1
Schubert, J1
Shnider, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery[NCT03760718]Early Phase 115 participants (Anticipated)Interventional2019-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for procaine and Fetal Death

ArticleYear
Embryo-lethal and teratogenic effect of the new platinum compound DPR in pregnant mice.
    Archives of toxicology, 2003, Volume: 77, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Bone and Bones; Cisplatin; Dose-Respons

2003
II. The advantages of local anesthesia for cesarean section (prenatal, neonatal, and developmental comparisons).
    South Dakota journal of medicine, 1975, Volume: 28, Issue:2

    Topics: Anesthesia, Conduction; Anesthesia, Local; Anesthesia, Obstetrical; Anesthesia, Spinal; Birth Weight

1975
Advantages of local anesthesia for cesarean section.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:2

    Topics: Anesthesia, Local; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Fetal Death; Humans;

1975
Paracervical block with low doses of chloroprocaine. Fetal and maternal effects.
    JAMA, 1975, Jan-06, Volume: 231, Issue:1

    Topics: Anesthesia, Obstetrical; Bradycardia; Cervix Uteri; Evaluation Studies as Topic; Female; Fetal Death

1975
[Animal experimental studies on preventive drug therapy of congenital cleft formation. I. Radiation-induced cleft palate in mice].
    Deutsche Zahn-, Mund-, und Kieferheilkunde mit Zentralblatt fur die gesamte Zahn-, Mund-, und Kieferheilkunde, 1972, Volume: 59, Issue:7

    Topics: Animals; Cleft Palate; Female; Fetal Death; Fetus; Gestational Age; Hypoxia; Injections, Intraperito

1972
New and interesting aspects of obstetric conduction anesthesia. A. Placental transfer of local anesthetics.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 25

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Animals; Fe

1966