procaine has been researched along with Dementia in 22 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the efficacy and adverse effects of procaine (and preparations containing procaine as a component) on cognitive function in the treatment of people with dementia as well as healthy elderly people." | 8.84 | Procaine treatments for cognition and dementia. ( Bereczki, D; Szatmári, S, 2008) |
| "To assess the efficacy and adverse effects of procaine (and preparations containing procaine as a component) on cognitive function in the treatment of people with dementia as well as healthy elderly people." | 4.84 | Procaine treatments for cognition and dementia. ( Bereczki, D; Szatmári, S, 2008) |
| "This article is a review and evaluation of the world literature on the systemic use of procaine in the treatment of the aging process and the common chronic diseases of later life." | 3.65 | The systemic use of procaine in the treatment of the elderly: a review. ( Ostfeld, A; Smith, CM; Stotsky, BA, 1977) |
| "1 years committed to a mental hospital for senile or arteriosclerotic psychoses, 11 received 2% procaine hydrochloride according to Aslan's method, for an average of 13 months, 11 for 6 months, and 10 normal saline." | 3.64 | Procaine (novocain) treatment of patients with senile and arteriosclerotic brain disease. ( CAHN, C; DEUTSCH, M; KRAL, VA; MUELLER, H; SOLYOM, L, 1962) |
| " This dosage was doubled to 10 ml per injection during the second six weeks." | 2.64 | Effects of a procaine preparation (Gerovital H3) in hospitalized geriatric patients: a double-blind study. ( Grossman, J; Hotz, M; Kling, R; Plutchik, R; Rubin, L; Siegel, B; Zwerling, I, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szatmári, S | 1 |
| Bereczki, D | 1 |
| CASHMAN, MD | 1 |
| LAWES, TG | 1 |
| PIRO, S | 1 |
| DI CRISTO, G | 1 |
| GRASSI, B | 1 |
| JIMENEZ BALGANON, F | 1 |
| KRAL, VA | 1 |
| CAHN, C | 1 |
| DEUTSCH, M | 1 |
| MUELLER, H | 1 |
| SOLYOM, L | 1 |
| WISNIEWSKA ROSZKOWSKA, K | 1 |
| SCHNEEBERGER, E | 1 |
| WOLFF, K | 1 |
| HABER, J | 1 |
| Reisberg, B | 1 |
| Ferris, SH | 1 |
| Gershon, S | 1 |
| Pavlova, SI | 1 |
| Jarvik, LF | 1 |
| Milne, JF | 1 |
| Ostfeld, A | 1 |
| Smith, CM | 1 |
| Stotsky, BA | 1 |
| Jansen, W | 1 |
| Zwerling, I | 1 |
| Plutchik, R | 1 |
| Hotz, M | 1 |
| Kling, R | 1 |
| Rubin, L | 1 |
| Grossman, J | 1 |
| Siegel, B | 1 |
| Jorgensen, O | 1 |
| Mabeck, CE | 1 |
| Andreasen, PB | 1 |
| Orgogozo, JM | 1 |
| Spiegel, R | 1 |
| Hollister, LE | 1 |
| Grujic, M | 1 |
| Perinovic, M | 1 |
| Wilde, KM | 1 |
| Albach, E | 1 |
4 reviews available for procaine and Dementia
| Article | Year |
|---|---|
Procaine treatments for cognition and dementia.
Topics: Aged; Cognition; Cognition Disorders; Dementia; Humans; Nootropic Agents; Procaine; Randomized Contr | 2008 |
THE CONFUSED GERIATRIC PATIENT.
Topics: Androgens; Dementia; Diagnosis, Differential; Estrogens; Geriatrics; Glutamates; Intracranial Arteri | 1964 |
Pharmacotherapy of senile dementia.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amphetamine; Antidepressive Agents, Tricyclic; Dementia | 1980 |
Critical review of clinical trials in senile dementia--I.
Topics: Central Nervous System Stimulants; Clinical Trials as Topic; Dementia; Humans; Meclofenoxate; Pirace | 1987 |
3 trials available for procaine and Dementia
| Article | Year |
|---|---|
[Analysis of the efficiency of Gerigoa-depot in a double-blind study].
Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Dementia; Drug Combinations; Drug Evalu | 1976 |
Effects of a procaine preparation (Gerovital H3) in hospitalized geriatric patients: a double-blind study.
Topics: Aged; Clinical Trials as Topic; Dementia; Depression; Female; Humans; Injections, Intramuscular; Int | 1975 |
Critical review of clinical trials in senile dementia--I.
Topics: Central Nervous System Stimulants; Clinical Trials as Topic; Dementia; Humans; Meclofenoxate; Pirace | 1987 |
16 other studies available for procaine and Dementia
| Article | Year |
|---|---|
A controlled trial of "gerioptil".
Topics: Dementia; Drug Combinations; Mental Disorders; Minerals; Procaine; Psychotic Disorders; Vitamins | 1961 |
[Contribution to the study of the treatment of neuropsychiatric forms of senility: procaine therapy].
Topics: Aging; Dementia; Mental Disorders; Procaine; Psychotic Disorders | 1960 |
[Trial of the procaine-PABA combination in the prevention and treatment of involutional processes].
Topics: 4-Aminobenzoic Acid; Biomedical Research; Dementia; Humans; Mental Disorders; Procaine; Psychotic Di | 1962 |
Procaine (novocain) treatment of patients with senile and arteriosclerotic brain disease.
Topics: Aged; Brain Diseases; Dementia; Depression; Female; Hospitals, Psychiatric; Humans; Intracranial Art | 1962 |
[A YEAR OF THERAPY IN A GERIATRIC WARD].
Topics: 4-Aminobenzoic Acid; Dementia; Geriatrics; Humans; Iron; Physical Fitness; Procaine; Psychotic Disor | 1963 |
[THERAPEUTIC EXPERIENCES WITH PROCAINE IN MENTAL AND PHYSICAL DISORDERS IN AGED PERSONS].
Topics: Dementia; Geriatrics; Humans; Intracranial Arteriosclerosis; Mental Disorders; Procaine; Psychotic D | 1964 |
Stellate ganglion infiltration in organic psychoses of late life.
Topics: Aged; Analgesia; Anesthesia; Anesthesia and Analgesia; Dementia; Disease; Ganglia, Autonomic; Humans | 1955 |
[Changes in coagulographic indices of patients with cerebral atherosclerosis complicated by mental disorders during the treatment process].
Topics: Aged; Aspirin; Blood Coagulation; Dementia; Drug Therapy, Combination; Female; Humans; Intracranial | 1980 |
Gerovital-H3--a review of the literature.
Topics: Aged; Aging; Anesthetics, Local; Anticholesteremic Agents; Dementia; Depression; Humans; Hydrogen-Io | 1975 |
The systemic use of procaine in the treatment of the elderly: a review.
Topics: 4-Aminobenzoic Acid; Adult; Affect; Aged; Aging; Arteriosclerosis; Arthritis; Chronic Disease; Demen | 1977 |
[Letter: Gerovital--procainehydrochloride].
Topics: Aged; Dementia; Humans; Procaine | 1975 |
[Gerovital H3, procaine chloride].
Topics: Dementia; Drug Evaluation; Female; Humans; Injections, Intramuscular; Middle Aged; Procaine | 1976 |
Alzheimer's disease. Is it worth treating?
Topics: Aged; Alzheimer Disease; Dementia; Dihydroergotoxine; Humans; Nafronyl; Papaverine; Pentoxifylline; | 1985 |
[Personal experiences with the preparation K.H.3-Geriatricum Schwarzhaupt in the therapy of geriatric diseases].
Topics: Age Factors; Aged; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Dementia; Drug Com | 1973 |
[Comments on a geriatric drug].
Topics: Aged; Asparagine; Aspartic Acid; Dementia; Drug Combinations; Female; Hematoporphyrins; Humans; Magn | 1974 |
[Treatment with Gerioptil and Gerioptil plus H3].
Topics: Adult; Age Factors; Aged; Dementia; Drug Combinations; Dysautonomia, Familial; Humans; Middle Aged; | 1971 |