procaine has been researched along with Corneal Diseases in 8 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Following minor surgery performed under topical application of oxybuprocaine (Dorsacaine, Novesin) two patients suffered from fibrinous iritis and moderate corneal swelling." | 7.67 | Fibrinous iritis due to oxybuprocaine. ( Haddad, R, 1989) |
| " While corneal complications following long-term use or misuse of local anaesthetic solutions have been described, toxic epitheliopathy after a single application of six drops of preservative free oxybuprocaine is rare." | 5.39 | Toxic epitheliopathy from a single application of preservative free oxybuprocaine (0.4%) in a patient with Sjogren's syndrome. ( Ansari, H; Spencer, N; Weinberg, L, 2013) |
| "Following minor surgery performed under topical application of oxybuprocaine (Dorsacaine, Novesin) two patients suffered from fibrinous iritis and moderate corneal swelling." | 3.67 | Fibrinous iritis due to oxybuprocaine. ( Haddad, R, 1989) |
| " Three patients presented to us with disciform keratitis, peripheral corneal ring, and stromal infiltration following the topical use of oxybuprocaine." | 3.67 | Oxybuprocaine keratopathy: a preventable disease. ( Penna, EP; Tabbara, KF, 1986) |
| "The diclofenac-treated group showed a statistically significant decrease in corneal sensitivity (p < 0." | 2.69 | The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects. ( Aragona, P; Ferreri, G; Laganà , E; Spinella, R; Tripodi, G, 2000) |
| " While corneal complications following long-term use or misuse of local anaesthetic solutions have been described, toxic epitheliopathy after a single application of six drops of preservative free oxybuprocaine is rare." | 1.39 | Toxic epitheliopathy from a single application of preservative free oxybuprocaine (0.4%) in a patient with Sjogren's syndrome. ( Ansari, H; Spencer, N; Weinberg, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ansari, H | 1 |
| Weinberg, L | 1 |
| Spencer, N | 1 |
| EM, S | 1 |
| Rao, SK | 1 |
| Wong, VW | 1 |
| Cheng, AC | 1 |
| Lam, PT | 1 |
| Lam, DS | 1 |
| Brewitt, H | 1 |
| Bonatz, E | 1 |
| Honegger, H | 1 |
| Aragona, P | 1 |
| Tripodi, G | 1 |
| Spinella, R | 1 |
| Laganà , E | 1 |
| Ferreri, G | 1 |
| Risco, JM | 1 |
| Millar, LC | 1 |
| Haddad, R | 1 |
| Penna, EP | 1 |
| Tabbara, KF | 1 |
1 trial available for procaine and Corneal Diseases
| Article | Year |
|---|---|
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; E | 2000 |
7 other studies available for procaine and Corneal Diseases
| Article | Year |
|---|---|
Toxic epitheliopathy from a single application of preservative free oxybuprocaine (0.4%) in a patient with Sjogren's syndrome.
Topics: Administration, Ophthalmic; Aged; Anesthetics, Local; Cataract Extraction; Corneal Diseases; Epithel | 2013 |
[Effect of novocain electrophoresis of the trigeminal nerve on trophism of the cornea].
Topics: Cornea; Corneal Diseases; Disease; Electrophoresis; Procaine; Trigeminal Nerve | 1953 |
Topical anesthesia-induced keratopathy after laser-assisted subepithelial keratectomy.
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Corneal Diseases; Female; Humans; Keratectomy, Subepit | 2007 |
Morphological changes of the corneal epithelium after application of topical anaesthetic ointments.
Topics: Anesthetics, Local; Animals; Cocaine; Corneal Diseases; Epithelium; Lidocaine; Microscopy, Electron, | 1980 |
Ultrastructural alterations in the endothelium in a patient with topical anesthetic abuse keratopathy.
Topics: Administration, Topical; Adult; Anesthetics, Local; Corneal Diseases; Endothelium, Corneal; Humans; | 1992 |
Fibrinous iritis due to oxybuprocaine.
Topics: Anesthetics, Local; Cataract Extraction; Corneal Diseases; Female; Humans; Iritis; Male; Middle Aged | 1989 |
Oxybuprocaine keratopathy: a preventable disease.
Topics: Adult; Anesthetics, Local; Corneal Diseases; Edema; Humans; Keratitis; Male; Ophthalmic Solutions; P | 1986 |