procaine has been researched along with Cerebral Ischemia in 6 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral ischemia induces membrane depolarization in the neuron, thereby incurring the simultaneous influx of various ions such as Na+ and Ca2+." | 1.30 | Improvement of ischemic damage in gerbil hippocampal neurons by procaine. ( Adachi, N; Arai, T; Chen, J; Liu, K; Nagaro, T, 1998) |
| "When procaine was used as a local anesthetic agent during surgery, damage to catecholamine-, GTP-, or forskolin-activated adenylate cyclase was evident to varying degrees in the frontal cortex, hippocampus or olfactory tubercle, but not in the nucleus accumbens and olfactory bulb of gerbils subjected to 60-min stroke followed by 15 or 150 min of recirculation." | 1.27 | Regional cyclic AMP systems during secondary ischemia in gerbils: influence of anesthetic agents. ( Callahan, AS; Christie-Pope, BC; Medina, MA; Palmer, GC; Palmer, SJ; Poulakos, L, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Oğuz, S | 1 |
| Aşgün, HF | 1 |
| Büyük, B | 1 |
| ROSNER, S | 1 |
| Christie-Pope, BC | 1 |
| Palmer, GC | 1 |
| Poulakos, L | 1 |
| Medina, MA | 1 |
| Callahan, AS | 1 |
| Palmer, SJ | 1 |
| Chen, J | 2 |
| Adachi, N | 2 |
| Liu, K | 1 |
| Nagaro, T | 1 |
| Arai, T | 2 |
| Nakanishi, K | 1 |
| Vinnitskiĭ, AR | 1 |
| Tsimenko, OA | 1 |
| Den'gub, VV | 1 |
6 other studies available for procaine and Cerebral Ischemia
| Article | Year |
|---|---|
Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions.
Topics: Animals; Biopsy; Brain; Brain Ischemia; Cardioplegic Solutions; Disease Models, Animal; Glucose; Mal | 2020 |
THE TREATMENT OF CEREBROVASCULAR INSUFFICIENCY BY INTRAVENOUS PROCAINE AND ANTIHISTAMINE COMPOUND.
Topics: Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; Diphenhydramine; Drug Therapy; Hista | 1964 |
Regional cyclic AMP systems during secondary ischemia in gerbils: influence of anesthetic agents.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Cyclic AMP; Evoked Potentials, Visual; Fasting; F | 1984 |
Improvement of ischemic damage in gerbil hippocampal neurons by procaine.
Topics: Anesthetics, Local; Animals; Brain Ischemia; Calcium; Electrophysiology; Gerbillinae; Hippocampus; I | 1998 |
Pre-ischaemic administration of procaine suppresses ischaemic glutamate release and reduces neuronal damage in the gerbil hippocampus.
Topics: Amino Acids; Anesthetics, Local; Animals; Brain Ischemia; Gerbillinae; Glutamic Acid; Hippocampus; M | 1999 |
[The mechanisms of speech recovery following revascularization surgery in patients having had an ischemic stroke].
Topics: Aphasia; Brain Ischemia; Cerebral Angiography; Cerebral Revascularization; Dominance, Cerebral; Huma | 1989 |