Page last updated: 2024-11-03

procaine and Cerebral Ischemia

procaine has been researched along with Cerebral Ischemia in 6 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Research Excerpts

ExcerptRelevanceReference
"Acute cerebral ischemia induces membrane depolarization in the neuron, thereby incurring the simultaneous influx of various ions such as Na+ and Ca2+."1.30Improvement of ischemic damage in gerbil hippocampal neurons by procaine. ( Adachi, N; Arai, T; Chen, J; Liu, K; Nagaro, T, 1998)
"When procaine was used as a local anesthetic agent during surgery, damage to catecholamine-, GTP-, or forskolin-activated adenylate cyclase was evident to varying degrees in the frontal cortex, hippocampus or olfactory tubercle, but not in the nucleus accumbens and olfactory bulb of gerbils subjected to 60-min stroke followed by 15 or 150 min of recirculation."1.27Regional cyclic AMP systems during secondary ischemia in gerbils: influence of anesthetic agents. ( Callahan, AS; Christie-Pope, BC; Medina, MA; Palmer, GC; Palmer, SJ; Poulakos, L, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Oğuz, S1
Aşgün, HF1
Büyük, B1
ROSNER, S1
Christie-Pope, BC1
Palmer, GC1
Poulakos, L1
Medina, MA1
Callahan, AS1
Palmer, SJ1
Chen, J2
Adachi, N2
Liu, K1
Nagaro, T1
Arai, T2
Nakanishi, K1
Vinnitskiĭ, AR1
Tsimenko, OA1
Den'gub, VV1

Other Studies

6 other studies available for procaine and Cerebral Ischemia

ArticleYear
Effectiveness of Brain Protection With Histidine-Tryptophan-Ketoglutarate Solutions.
    The heart surgery forum, 2020, Jul-22, Volume: 23, Issue:4

    Topics: Animals; Biopsy; Brain; Brain Ischemia; Cardioplegic Solutions; Disease Models, Animal; Glucose; Mal

2020
THE TREATMENT OF CEREBROVASCULAR INSUFFICIENCY BY INTRAVENOUS PROCAINE AND ANTIHISTAMINE COMPOUND.
    Vascular diseases, 1964, Volume: 1

    Topics: Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; Diphenhydramine; Drug Therapy; Hista

1964
Regional cyclic AMP systems during secondary ischemia in gerbils: influence of anesthetic agents.
    Experimental neurology, 1984, Volume: 84, Issue:3

    Topics: Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Cyclic AMP; Evoked Potentials, Visual; Fasting; F

1984
Improvement of ischemic damage in gerbil hippocampal neurons by procaine.
    Brain research, 1998, May-04, Volume: 792, Issue:1

    Topics: Anesthetics, Local; Animals; Brain Ischemia; Calcium; Electrophysiology; Gerbillinae; Hippocampus; I

1998
Pre-ischaemic administration of procaine suppresses ischaemic glutamate release and reduces neuronal damage in the gerbil hippocampus.
    British journal of anaesthesia, 1999, Volume: 83, Issue:3

    Topics: Amino Acids; Anesthetics, Local; Animals; Brain Ischemia; Gerbillinae; Glutamic Acid; Hippocampus; M

1999
[The mechanisms of speech recovery following revascularization surgery in patients having had an ischemic stroke].
    Vrachebnoe delo, 1989, Issue:9

    Topics: Aphasia; Brain Ischemia; Cerebral Angiography; Cerebral Revascularization; Dominance, Cerebral; Huma

1989