procaine has been researched along with Blood Pressure, Low in 35 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
Excerpt | Relevance | Reference |
---|---|---|
"The purpose of this study was to determine, by continual reassessment, the 90% effective dose (ED90) of phenylephrine for hypotension after combined spinal-epidural anesthesia." | 7.81 | Determination of the 90% effective dose (ED90) of phenylephrine for hypotension during elective cesarean delivery using a continual reassessment method. ( Diao, M; Huang, Y; Li, H; Lin, X; Liu, H; Ma, Y; Zhou, J, 2015) |
"The purpose of this study was to determine, by continual reassessment, the 90% effective dose (ED90) of phenylephrine for hypotension after combined spinal-epidural anesthesia." | 3.81 | Determination of the 90% effective dose (ED90) of phenylephrine for hypotension during elective cesarean delivery using a continual reassessment method. ( Diao, M; Huang, Y; Li, H; Lin, X; Liu, H; Ma, Y; Zhou, J, 2015) |
"The incidence and degree of hypotension, time to establish surgical analgesia, and several other maternal and fetal variables were studied when 2-chloroprocaine, 3 per cent, and bupivacaine, 0." | 3.66 | Chloroprocaine vs. bupivacaine for lumbar epidural analgesia for elective cesarean section. ( Dewan, DM; Floyd, HM; Grant, WM; James, FM; Rhyne, L; Westmoreland, RT; Wheeler, AS, 1980) |
"Chloroprocaine was comparable with plain 0." | 2.79 | Intrathecal 1% 2-chloroprocaine vs. 0.5% bupivacaine in ambulatory surgery: a prospective, observer-blinded, randomised, controlled trial. ( Camponovo, C; Cristina, D; Fanelli, A; Fanelli, G; Ghisi, D; Leschka, K; Riva, T; Vassiliou, T; Wulf, H, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (77.14) | 18.7374 |
1990's | 1 (2.86) | 18.2507 |
2000's | 3 (8.57) | 29.6817 |
2010's | 4 (11.43) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Camponovo, C | 1 |
Wulf, H | 1 |
Ghisi, D | 1 |
Fanelli, A | 1 |
Riva, T | 1 |
Cristina, D | 1 |
Vassiliou, T | 1 |
Leschka, K | 1 |
Fanelli, G | 1 |
Fukushima, A | 1 |
Chazono, K | 1 |
Hashimoto, Y | 1 |
Iwajima, Y | 1 |
Yamamoto, S | 1 |
Maeda, Y | 1 |
Ohsawa, M | 1 |
Ono, H | 1 |
Liu, H | 1 |
Huang, Y | 1 |
Diao, M | 1 |
Li, H | 1 |
Ma, Y | 1 |
Lin, X | 1 |
Zhou, J | 1 |
Ghafaripour, S | 1 |
Sahmeddini, MA | 1 |
Lahsaee, SM | 1 |
Khosravi, MB | 1 |
Sattari, H | 1 |
Nikeghbalian, S | 1 |
Shokrizadeh, S | 1 |
Malekhosseine, SA | 1 |
MASON, AA | 1 |
PELMORE, JF | 1 |
ASERMAN, D | 1 |
KERR, WJ | 1 |
LAGEN, JB | 1 |
DOCAL, JC | 1 |
ARRIEN ECHEVARRI, A | 1 |
LEWIS, JM | 1 |
REES, GA | 1 |
SLEIGHT, P | 1 |
CAMPBELL, JR | 1 |
LAWSON, DD | 1 |
SANFORD, J | 1 |
BERGMANN, KH | 1 |
LITWIN, J | 1 |
Lee, JS | 1 |
Harding, RE | 1 |
Bjørnestad, E | 1 |
Iversen, OL | 1 |
Raeder, J | 1 |
Fu, RQ | 1 |
Tian, YK | 1 |
Fang, WR | 1 |
Meĭerovich, SI | 1 |
Begara Mesa, D | 1 |
Vilar Rodriguez, MA | 1 |
Anshelevich, IuV | 1 |
Dumesh, SZ | 1 |
Slaĭdyn', AK | 1 |
Sporan, VG | 1 |
Abboud, TK | 1 |
Khoo, SS | 1 |
Miller, F | 1 |
Doan, T | 1 |
Henriksen, EH | 1 |
James, FM | 1 |
Dewan, DM | 1 |
Floyd, HM | 1 |
Wheeler, AS | 1 |
Grant, WM | 1 |
Rhyne, L | 1 |
Westmoreland, RT | 1 |
Conklin, KA | 1 |
van der Wal, C | 1 |
Ku, YH | 1 |
Zhang, T | 1 |
McAllister, CJ | 1 |
Petin, GI | 1 |
Strelets, BM | 1 |
Krasavin, VA | 1 |
MacLachlan, D | 1 |
Forrest, AL | 1 |
Sehhati, G | 1 |
Frey, R | 1 |
Mildner, R | 1 |
Ahlgren, P | 1 |
Praestholm, J | 1 |
Foussard-Blanpin, O | 1 |
Bretaudeau, J | 1 |
Rosner, S | 1 |
Borodianskiĭ, VI | 1 |
Fukunaga, AF | 1 |
Epstein, RM | 1 |
Shnider, SM | 1 |
Bartelheimer, HK | 1 |
Bauditz, W | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Chloroprocaine Versus Bupivacaine Spinal Anesthesia for Cervical Cerclage[NCT02862912] | Phase 4 | 43 participants (Actual) | Interventional | 2016-11-08 | Completed | ||
Low Epidural Anesthesia With Chloroprocaine Versus Lidocaine: a Prospective, Randomized, Double-blinded Multi-centre Clinical Trial in China[NCT02287870] | Phase 4 | 120 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Time from spinal anesthesia placement to ability to ambulate. (NCT02862912)
Timeframe: 5 hours
Intervention | minutes (Median) |
---|---|
Chloroprocaine (CP) | 158 |
Bupivacaine (BUP) | 229 |
"The mean difference between groups in time between the end of spinal injection (t IT) to time for no motor block (t motor), i.e. tIT - T motor. Motor block will be assessed using the Bromage scale:~Bromage Scale I = free movement of the legs and feet = no block II = able to flex knees, with free movement of feet = partial (33%) block III = unable to flex knees, but with free movement of the feet = almost complete (66%) block IV = unable to move legs or feet = complete block (100%)" (NCT02862912)
Timeframe: 3 hours
Intervention | minutes (Median) |
---|---|
Chloroprocaine (CP) | 109 |
Bupivacaine (BUP) | 112 |
Time from spinal anesthesia injection to ability to void spontaneously. (NCT02862912)
Timeframe: 5 hours
Intervention | minutes (Median) |
---|---|
Bupivacaine (BUP) | 229 |
Chloroprocaine (CP) | 158 |
1 review available for procaine and Blood Pressure, Low
Article | Year |
---|---|
[Extradural anesthesia in cesarean operations].
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Section; Ep | 1982 |
4 trials available for procaine and Blood Pressure, Low
Article | Year |
---|---|
Intrathecal 1% 2-chloroprocaine vs. 0.5% bupivacaine in ambulatory surgery: a prospective, observer-blinded, randomised, controlled trial.
Topics: Abdomen; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Spinal | 2014 |
Hypotension after reperfusion in liver transplantation: histidine-tryptophan-ketoglutarate versus University of Wisconsin solution.
Topics: Adenosine; Adult; Allopurinol; Blood Gas Analysis; Female; Glucose; Glutathione; Hemodynamics; Human | 2010 |
Similar onset time of 2-chloroprocaine and lidocaine + epinephrine for epidural anesthesia for elective Cesarean section.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Cesarean Section; Double-B | 2006 |
Combined spinal and epidural anaesthesia with chloroprocaine for hysterectomy.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Dose-Response Relationship, Dru | 2008 |
30 other studies available for procaine and Blood Pressure, Low
Article | Year |
---|---|
Oseltamivir produces hypothermic and neuromuscular effects by inhibition of nicotinic acetylcholine receptor functions: comparison to procaine and bupropion.
Topics: Animals; Bradycardia; Bupropion; Drug Synergism; Fever; Hypotension; Male; Mice; Muscle Relaxation; | 2015 |
Determination of the 90% effective dose (ED90) of phenylephrine for hypotension during elective cesarean delivery using a continual reassessment method.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Apgar | 2015 |
Combined use of hexamethonium bromide and procaine amide in controlled hypotension; a preliminary report.
Topics: Cardiovascular Agents; Hexamethonium; Hypotension; Hypotension, Controlled; Muscle Relaxants, Centra | 1953 |
Controlled hypotension in neurosurgery with hexamethonium and procaine amide.
Topics: Cardiovascular Agents; Hexamethonium; Hypotension; Hypotension, Controlled; Muscle Relaxants, Centra | 1953 |
Cardiovascular diseases.
Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular Sy | 1953 |
[Controlled hypotension with novocaine and pendiomide].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Autonomic Agents; Hypotension; Hypotension, Control | 1954 |
[Intravenous novocaine and induced arterial hypotension].
Topics: Hypotension; Hypotension, Controlled; Procaine | 1957 |
ELECTROCARDIOGRAPHY DURING POSTERIOR FOSSA OPERATIONS.
Topics: Arrhythmias, Cardiac; Electrocardiography; Embolism; Embolism, Air; Humans; Hypotension; Infant; Lid | 1964 |
A CARDIOVASCULAR DEPRESSOR REFLEX FROM THE EPICARDIUM OF THE LEFT VENTRICLE IN THE DOG.
Topics: Alkaloids; Atropine; Blood Pressure; Bradycardia; Cold Temperature; Coronary Vessels; Dogs; Heart; H | 1964 |
INVESTIGATION OF RESPIRATORY AND CIRCULATORY EFFECTS OF ETHAMIVAN IN THE DOG AND CAT.
Topics: Amines; Aorta; Apnea; Atropine; Benzamides; Blood Pressure; Bradycardia; Carotid Arteries; Cats; Cen | 1964 |
[ON THE QUESTION OF A BLOOD-SPARING OPERATION METHOD IN THE VAGINALPERINEAL AREA].
Topics: Anesthesia; Anesthesia, Local; Anesthesiology; Female; Humans; Hypotension; Hypotension, Controlled; | 1964 |
[Effect of adrenaline administered after adrenolytic drug on hypotensive action of autohemolysates in cats].
Topics: Adrenergic Antagonists; Animals; Blood Pressure; Blood Pressure Determination; Cats; Epinephrine; He | 1954 |
Spinal anesthesia in severe preeclampsia.
Topics: Anesthesia, Spinal; Female; Humans; Hypotension; Pre-Eclampsia; Pregnancy; Procaine | 2004 |
[Experience in the treatment of trigeminal neuralgia with aminazine].
Topics: Adult; Aged; Analgesics; Chlorpromazine; Female; Humans; Hypotension; Injections, Intramuscular; Mal | 1966 |
[Complications after intravenous administration of anti-arrhythmia agents].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Ad | 1982 |
Maternal, fetal, and neonatal responses after epidural anesthesia with bupivacaine, 2-chloroprocaine, or lidocaine.
Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Behavior; Bupi | 1982 |
Chloroprocaine vs. bupivacaine for lumbar epidural analgesia for elective cesarean section.
Topics: Analgesia; Anesthesia, Epidural; Apgar Score; Blood Gas Analysis; Bupivacaine; Cesarean Section; Eph | 1980 |
Epidural anaesthesia with chloroprocaine. Delayed onset, extensive spread, and prolonged duration.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Hypotension; Pregnancy; Procai | 1980 |
Brain atriopeptin mediates AV3V depressor response.
Topics: Animals; Atrial Natriuretic Factor; Atropine Derivatives; Blood Pressure; Cerebral Ventricles; Drug | 1994 |
Adverse reactions to commonly prescribed drugs in patients with renal insufficiency.
Topics: Analgesics; Anti-Bacterial Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Drug-Related Side | 1977 |
[Suppression of cardiac activity and respiration during conduction anesthesia].
Topics: Anesthesia, Conduction; Arteriosclerosis Obliterans; Humans; Hypotension; Leg; Lidocaine; Male; Midd | 1989 |
Letter: Procaine and malignant hyperthermia.
Topics: Dose-Response Relationship, Drug; Female; Humans; Hypotension; Injections, Intravenous; Malignant Hy | 1974 |
[Complications of regional anaesthesia and their treatment (author's transl)].
Topics: Adrenal Cortex Hormones; Anesthesia, Local; Apnea; Barbiturates; Bradycardia; Bupivacaine; Diagnosis | 1973 |
[Complications of myelography with methiodal].
Topics: Adult; Anesthesia, Spinal; Blood Pressure; Female; Headache; Humans; Hypotension; Male; Mesylates; M | 1969 |
[Study of the mechanism of hypotension induced in certain conditions by epsilon-aminocaproic acid].
Topics: Aminocaproates; Animals; Atropine; Dogs; Ethanolamines; Hypotension; Phenylbutazone; Procaine; Prome | 1966 |
The diagnosis and treatment of cerebral concussion.
Topics: Ascorbic Acid; Aspirin; Brain Concussion; Cerebral Ventriculography; Cortisone; Diphenhydramine; Ele | 1967 |
[The therapy and prevention of acute renal insufficiency in traumatic shock].
Topics: Acute Kidney Injury; Adult; Autonomic Nerve Block; Diuresis; Female; Histamine H1 Antagonists; Human | 1966 |
Effects of cyclopropane on the sympathetic nervous system and on neural regulation of circulation in the cat.
Topics: Action Potentials; Animals; Aorta; Arrhythmias, Cardiac; Blood; Blood Circulation; Blood Pressure; B | 1974 |
New and interesting aspects of obstetric conduction anesthesia. A. Placental transfer of local anesthetics.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Animals; Fe | 1966 |
[Treatment of imipramine poisoning at childhood].
Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot | 1970 |