Page last updated: 2024-11-03

procaine and Asystole

procaine has been researched along with Asystole in 41 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Research Excerpts

ExcerptRelevanceReference
"Cardiac arrest was induced in female large white pigs by intravenous injection of potassium chloride."1.46An Oxygenated and Transportable Machine Perfusion System Fully Rescues Liver Grafts Exposed to Lethal Ischemic Damage in a Pig Model of DCD Liver Transplantation. ( Azoulay, D; Ben Mosbah, I; Calderaro, J; Cohen, JL; Compagnon, P; Corlu, A; Disabato, M; Feray, C; Hentati, H; Levesque, E, 2017)
"Cardiac arrest was induced either with HTK (n = 10), HTK-N (n = 10) or HTK-N + S-NO-HSA (n = 10)."1.42The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats. ( Aumayr, K; Dzilic, E; Gasser, H; Hallström, S; Kerjaschki, D; Kreibich, M; Pelzmann, B; Podesser, BK; Trescher, K, 2015)
"After selective cardiac arrest with Bretschneider, captopril-treated hearts showed improved hemodynamics compared to control and the other treatment groups."1.40Acute hemodynamic effects of angiotensin- converting enzyme inhibition after prolonged cardiac arrest with Bretschneider's solution. ( Dhein, S; Hoyer, A; Kempfert, J; Mohr, FW; Pritzwald-Stegmann, P, 2014)
"Cardiac arrest was electrically induced in anaesthetized German landrace pigs (20-25 kg bw)."1.33Kidney transplantation from non-heart-beating donors after oxygenated low-flow machine perfusion preservation with histidine-tryptophan-ketoglutarate solution. ( Dombrowski, F; Minor, T; Sitzia, M, 2005)
"Kidneys were harvested 40 minutes after cardiac arrest in German Landrace pigs and subjected to 18 hours of oxygenated hypothermic machine perfusion with either Belzer MPS or modified HTK via the renal artery (Psys < 40 mm Hg)."1.33Oxygenated machine perfusion preservation of predamaged kidneys with HTK and Belzer machine perfusion solution: an experimental study in pigs. ( Leuvenink, H; Manekeller, S; Minor, T; Sitzia, M, 2005)
"Phentolamine was found to reduce heterogeneity of organ microperfusion."1.31Heparin and phentolamine combined, rather than heparin alone, improves hepatic microvascular procurement in a non-heart-beating donor rat-model. ( Menger, MD; Minor, T; Richter, S; Vollmar, B; Yamauchi, J, 2000)
"After 60 min of cardiac arrest, rat livers were perfused by gravity (60 cm H2O) via the portal vein with either 60 ml of HTK, 20 ml of UW, or 20 ml of Ringer's solution (22 degrees C including 7500U of streptokinase) and, subsequently, 20 ml of UW."1.31Fibrinolytic preflush upon liver retrieval from non-heart beating donors to enhance postpreservation viability and energetic recovery upon reperfusion. ( Akbar, S; Hachenberg, A; Minor, T; Pauleit, D; Tolba, R, 2001)
"Rabbit hearts were subjected to cardiac arrest induced by injecting 3 isotonic cardioplegic solutions each of which contained in combination with procaine-HCl one of 3 different magnesium compounds."1.26Reperfusion effects on the magnesium-procaine arrested rabbit heart. ( Hölscher, B, 1981)
"An exceptionally serious case of malignant hyperthermia in a 17 year old male is presented."1.26[Malignant hyperthermia. A case report (author's transl)]. ( Rettig, B; Weitz, H, 1980)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199023 (56.10)18.7374
1990's6 (14.63)18.2507
2000's8 (19.51)29.6817
2010's4 (9.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Compagnon, P1
Levesque, E1
Hentati, H1
Disabato, M1
Calderaro, J1
Feray, C1
Corlu, A1
Cohen, JL1
Ben Mosbah, I1
Azoulay, D1
Wang, D1
Zhang, X1
Qu, D1
Han, J1
Meng, F1
Xu, M1
Zheng, Q1
Hoyer, A1
Kempfert, J1
Pritzwald-Stegmann, P1
Mohr, FW1
Dhein, S1
Trescher, K1
Dzilic, E1
Kreibich, M1
Gasser, H1
Aumayr, K1
Kerjaschki, D1
Pelzmann, B1
Hallström, S1
Podesser, BK1
Yotsumoto, G1
Jeschkeit-Schubbert, S1
Funcke, C1
Kuhn-Régnier, F1
Fischer, JH1
GAQUIERE, A1
RYAN, ML1
SALVADOR, RA1
WHITE, CW1
SCHIESSLE, W1
NAHAS, GG1
MONDINI, P1
ZACCARINI, C1
CAVALLONI, L1
ZILIOTTO, P1
PORRO, A1
GRIFFITHS, JC1
PAVAN, WL1
MARCHAND, P1
FICK, W1
ROUALLE, HL1
ALEXANDER, L1
HEWER, CL1
Minor, T6
Sitzia, M2
Dombrowski, F1
Manekeller, S1
Leuvenink, H1
Wilson, CH1
Asher, JF1
Gupta, A1
Vijayanand, D1
Wyrley-Birch, H1
Stamp, S1
Rix, DA1
Soomro, N1
Manas, DM1
Jaques, BC1
Peaston, R1
Talbot, D1
Hölscher, B1
Rettig, B1
Weitz, H1
Leblanc, M1
Pichette, V1
Madore, F1
Ouimet, D1
Geadah, D1
Cardinal, J1
Brown, DL1
Ransom, DM1
Hall, JA1
Leicht, CH1
Schroeder, DR1
Offord, KP1
Kober, IM1
Obermayr, RP1
Spieckermann, PG1
Moisiuk, Y1
Tarabarko, N1
Vitjazev, G1
Sharshatkin, A1
Aroutiounian, S1
Shumakov, V1
Koyama, I1
Ogawa, N1
Watanabe, T1
Taguchi, Y1
Asami, H1
Nagashima, N1
Shinozuka, N1
Omoto, R1
Saad, S1
Kötting, M1
Nagelschmidt, M1
Isselhard, W1
Richter, S2
Yamauchi, J2
Menger, MD2
Vollmar, B2
Stoletzki, S1
Schmiedl, A1
Richter, J1
Hachenberg, A1
Tolba, R1
Pauleit, D1
Akbar, S1
Verin, P1
Vildy, A1
Marx, C1
Barlier, S1
Döring, V1
Bleese, N1
Gercken, G1
Kalmár, P1
Lierse, W1
Pokar, H1
Rodewald, G1
Krause, EG1
Hübner, G1
Martínková, J1
Grossmann, V1
Goutier, R1
Reidemeister, JC1
Rau, G1
Grebe, D2
Orellano, LE2
Birch, AA1
Mitchell, GD1
Playford, GA1
Lang, CA1
Dixon, TC1
Bonhoeffer, K1
Bretschneider, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Immune Response of Breast Cancer Patients Treated With Levobupivacaine Using Paravertebral or Superficial Chest Blocks[NCT05816538]100 participants (Anticipated)Interventional2023-04-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for procaine and Asystole

ArticleYear
[CARDIAC RESUSCITATION. CURRENT STATUS].
    Hospital (Rio de Janeiro, Brazil), 1963, Volume: 64

    Topics: Electric Stimulation Therapy; Epinephrine; Heart Arrest; Heart Massage; Humans; Hypothermia; Hypothe

1963
Electron microscopic investigation of cardioplegia. Electron microscopy of various forms of cardiac arrest in correlation with myocardial function.
    Methods and achievements in experimental pathology, 1971, Volume: 5

    Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Citrates; Coronary Disease; Disease Models, Animal; D

1971

Trials

1 trial available for procaine and Asystole

ArticleYear
Changes in serum potassium response to succinylcholine following trauma.
    JAMA, 1969, Oct-20, Volume: 210, Issue:3

    Topics: Burns; Carbon Dioxide; Fractures, Bone; Heart Arrest; Humans; Hyperkalemia; Injections, Intravenous;

1969

Other Studies

38 other studies available for procaine and Asystole

ArticleYear
An Oxygenated and Transportable Machine Perfusion System Fully Rescues Liver Grafts Exposed to Lethal Ischemic Damage in a Pig Model of DCD Liver Transplantation.
    Transplantation, 2017, Volume: 101, Issue:7

    Topics: Allografts; Animals; Biomarkers; Disease Models, Animal; Energy Metabolism; Equipment Design; Female

2017
Astragalin and dihydromyricetin as adjuncts to histidine‑tryptophan‑ketoglutarate cardioplegia enhances protection during cardioplegic arrest.
    Molecular medicine reports, 2018, Volume: 18, Issue:3

    Topics: Animals; Apoptosis; Biomarkers; Cardioplegic Solutions; Cardiotonic Agents; Cytokines; Disease Model

2018
Acute hemodynamic effects of angiotensin- converting enzyme inhibition after prolonged cardiac arrest with Bretschneider's solution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:12

    Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhib

2014
The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats.
    Interactive cardiovascular and thoracic surgery, 2015, Volume: 20, Issue:3

    Topics: Animals; Cardiac Output; Cardioplegic Solutions; Disease Models, Animal; Glucose; Heart Arrest; Hear

2015
Total recovery of heart grafts of non-heart-beating donors after 3 hours of hypothermic coronary oxygen persufflation preservation in an orthotopic pig transplantation model.
    Transplantation, 2003, Mar-27, Volume: 75, Issue:6

    Topics: Animals; Diacetyl; Glucose; Heart Arrest; Heart Transplantation; Heart-Lung Machine; Hypothermia, In

2003
[Benign ventricular paroxysmal tachycardia in a child and arrested with pronestyl].
    Archives des maladies du coeur et des vaisseaux, 1952, Volume: 45, Issue:6

    Topics: Child; Heart Arrest; Humans; Infant; Procainamide; Procaine; Tachycardia; Tachycardia, Paroxysmal; T

1952
Cardiac resuscitation following experimental arrest by procaine and ether.
    Circulation, 1955, Volume: 11, Issue:1

    Topics: Ether; Ethers; Heart Arrest; Humans; Procaine; Resuscitation

1955
[Experimental study of electroshock therapy of ventricular fibrillation].
    Zeitschrift fur die gesamte experimentelle Medizin, 1956, Volume: 127, Issue:1

    Topics: Cardiovascular Diseases; Convulsive Therapy; Electricity; Electroconvulsive Therapy; Epinephrine; He

1956
[Pharmacological cardiac arrest in cardiac surgery].
    La Presse medicale, 1957, Jan-19, Volume: 65, Issue:6

    Topics: Acetylcholine; Adenosine Triphosphate; Cardiac Surgical Procedures; Heart Arrest; Humans; Procaine;

1957
Reversal of ventricular fibrillation without an electrical defibrillator.
    Scottish medical journal, 1962, Volume: 7

    Topics: Chlorides; Defibrillators; Electric Countershock; Epinephrine; Heart Arrest; Humans; Procaine; Ventr

1962
CARDIAC ARREST AND RESUSCITATION.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1964, Jul-18, Volume: 38

    Topics: Calcium; Electric Stimulation Therapy; Epinephrine; Equipment and Supplies; Heart Arrest; Heart Mass

1964
[HEART ARREST AFTER LOCAL ANESTHESIA].
    Zentralblatt fur Chirurgie, 1965, May-15, Volume: 90

    Topics: Anesthesia, Local; Heart Arrest; Hyperthyroidism; Pregnancy; Procaine; Toxicology

1965
A case of cardiac arrest; vagal inhibition relieved by procaine.
    British medical journal, 1950, Sep-23, Volume: 2, Issue:4681

    Topics: Heart; Heart Arrest; Procaine

1950
A treatment of cardiac arrest.
    British medical journal, 1952, Sep-06, Volume: 2, Issue:4783

    Topics: Heart Arrest; Humans; Procaine

1952
Kidney transplantation from non-heart-beating donors after oxygenated low-flow machine perfusion preservation with histidine-tryptophan-ketoglutarate solution.
    Transplant international : official journal of the European Society for Organ Transplantation, 2005, Volume: 17, Issue:11

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Endothelium, Vascular; Glucose; Glutathione

2005
Oxygenated machine perfusion preservation of predamaged kidneys with HTK and Belzer machine perfusion solution: an experimental study in pigs.
    Transplantation proceedings, 2005, Volume: 37, Issue:8

    Topics: Adenosine; Allopurinol; Animals; Glucose; Glutathione; Heart Arrest; In Vitro Techniques; Insulin; K

2005
Comparison of HTK and hypertonic citrate to intraarterial cooling in human non-heart-beating kidney donors.
    Transplantation proceedings, 2007, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Child; Cohort Studies; Female; Glucose; Heart Arrest; Humans; Hypertonic Solution

2007
Reperfusion effects on the magnesium-procaine arrested rabbit heart.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:11

    Topics: Animals; Electrocardiography; Glycogen; Heart Arrest; Lactates; Lactic Acid; Magnesium; Mitochondria

1981
[Malignant hyperthermia. A case report (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:2

    Topics: Adolescent; Halothane; Heart Arrest; Hemorrhagic Disorders; Humans; Ice; Male; Malignant Hyperthermi

1980
N-acetylprocainamide intoxication with torsade de pointes treated by high dialysate flow rate continuous arteriovenous hemodiafiltration.
    Critical care medicine, 1995, Volume: 23, Issue:3

    Topics: Acecainide; Aged; Atrial Fibrillation; Heart Arrest; Hemodiafiltration; Humans; Male; Procaine; Tors

1995
Regional anesthesia and local anesthetic-induced systemic toxicity: seizure frequency and accompanying cardiovascular changes.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Adult; Anesthesia, Caudal; Anesthesia, Epidural; Anesthetics; Anesthetics, Local; Blood Pressure; Br

1995
How beneficial is the reduction of edema formation by polyethylene glycol during cardioplegic arrest?
    Transplantation proceedings, 1996, Volume: 28, Issue:1

    Topics: Animals; Blood Pressure; Cardioplegic Solutions; Coronary Circulation; Edema; Glucose; Heart; Heart

1996
Histidine-tryptophan-ketoglutarate versus Euro-Collins for preservation of kidneys from non-heart-beating donors.
    Transplantation proceedings, 1996, Volume: 28, Issue:1

    Topics: Adult; Cause of Death; Cerebral Hemorrhage; Craniocerebral Trauma; Female; Glucose; Heart Arrest; Hu

1996
Utilization of warm ischemic livers from non-heart beating donors by portable cardiopulmonary bypass and heterotopic transplantation.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Adenosine; Allopurinol; Animals; Bile Ducts; Bilirubin; Cardiopulmonary Bypass; Dogs; Glucose; Gluta

1996
Short-term restoration by gaseous oxygen for long-term preservation of predamaged livers from non-heart-beating donors.
    Transplantation proceedings, 1997, Volume: 29, Issue:8

    Topics: Adenine Nucleotides; Animals; Energy Metabolism; Glucose; Heart Arrest; Liver; Male; Mannitol; Organ

1997
Heparin/phentolamine does not improve kidney perfusion with HTK solution after prolonged warm ischemia in a rat non-heart-beating donor model.
    Transplantation proceedings, 2000, Volume: 32, Issue:1

    Topics: Animals; Glucose; Heart Arrest; Heparin; Ischemia; Kidney; Liver Circulation; Mannitol; Microcircula

2000
Heparin and phentolamine combined, rather than heparin alone, improves hepatic microvascular procurement in a non-heart-beating donor rat-model.
    Transplant international : official journal of the European Society for Organ Transplantation, 2000, Volume: 13, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Female; Glucose; Heart Arrest; Heparin;

2000
Intercalated clear cells or pale cells in the sinus node of canine hearts? An ultrastructural study.
    The Anatomical record, 2000, 09-01, Volume: 260, Issue:1

    Topics: Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Dogs; Female; Glucose; Heart; Heart

2000
Fibrinolytic preflush upon liver retrieval from non-heart beating donors to enhance postpreservation viability and energetic recovery upon reperfusion.
    Transplantation, 2001, Jun-27, Volume: 71, Issue:12

    Topics: Adenosine; Allopurinol; Animals; Energy Metabolism; Fibrinolytic Agents; Glucose; Glutathione; Heart

2001
[Complications of local anesthetics].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Cocaine; Dose-Response Relationship, Drug; Drug Hypersensitivity; F

1976
[Active exchange of Na and K in perfused and procaine arrested rat heart].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:5

    Topics: Animals; Biological Transport, Active; Heart Arrest; Myocardium; Perfusion; Potassium; Procaine; Rat

1975
[Metabolism and ultrastructure of magnesium aspartate-procaine arrested hearts of rabbit and man (author's transl)].
    Thoraxchirurgie, vaskulare Chirurgie, 1975, Volume: 23, Issue:3

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Coronary Disease; Glycogen; Hea

1975
[Biochemical changes in cardiac arrest].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jan-01, Volume: 24, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Dogs; Glucosyltransferases; Glyceraldehyde-3-Phosphate Deh

1969
Effects of novocain on the isolated perfused heart of rats after X-irradiation.
    Strahlentherapie, 1971, Volume: 141, Issue:1

    Topics: Action Potentials; Aminobenzoates; Animals; Biotransformation; Bradycardia; Cholinesterases; Esteras

1971
[Electrocardiographic findings following cardioplegia caused by extracellular sodium and calcium deprivation and novocaine administration].
    Thoraxchirurgie und vaskulare Chirurgie, 1966, Volume: 14, Issue:6

    Topics: Adult; Animals; Dogs; Electrocardiography; Heart Arrest; Heart Conduction System; Humans; Hypocalcem

1966
Cardiac arrest: experience and results in emergency treatment outside the operating theatre.
    The Medical journal of Australia, 1970, Apr-11, Volume: 1, Issue:15

    Topics: Adolescent; Adult; Aged; Atropine; Bicarbonates; Coronary Care Units; Craniocerebral Trauma; Death;

1970
[The oxygen consumption of normal and hypothermic dog hearts before and during different forms of induced cardiac arrest].
    Bibliotheca cardiologica, 1967, Volume: 18

    Topics: Animals; Blood Gas Analysis; Calcium; Cell Membrane; Dogs; Electrocardiography; Heart Arrest; Hypoth

1967
[Continuous measurement of potassium and sodium losses of the myocardium during a heart arrest by coronary perfusion with low sodium, calcium-free, procaine containing, oxygen saturated cardioplegic solutions].
    Archiv fur Kreislaufforschung, 1967, Volume: 53, Issue:3

    Topics: Animals; Arteries; Coronary Vessels; Dogs; Female; Heart; Heart Arrest; Heart Arrest, Induced; Male;

1967