procaine and Arrhythmias, Cardiac studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

Excerpt	Relevance	Reference
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."	7.91	Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)
"Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery."	6.68	Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery. ( Berg, EM; Levang, OW; Sellevold, OF, 1995)
"The reduction in hypothermia and ischaemia-induced reperfusion arrhythmias by the addition of sevoflurane to HTK solution may be related to the phosphorylation of Cx43 at serine 368."	3.91	Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. ( Gao, H; Gao, J; Li, WC; Wang, ZJ, 2019)
" An epidural anaesthetic using 3-chloroprocaine produced a safe and satisfactory anaesthetic for the procedure in a patient prone to ventricular arrhythmias and cardiac arrest."	3.67	Anaesthesia for caesarean section in a patient with Jervell, Lange-Nielsen syndrome. ( Ryan, H, 1988)
" Acute pretreatment with bretylium, 20 mg/kg intravenously, significantly increased the amount of infused ouabain required before the appearance of the first signs of atrial arrhythmia in anaesthetized guinea-pigs, but did not prevent ventricular arrhythmias."	3.65	The effect of bretylium on intracellular cardiac action potentials in relation to its anti-arrhythmic and local anaesthetic activity. ( Papp, JG; Vaughan Williams, EM, 1969)
"33."	2.87	Role of terminal warm blood cardioplegia in complex congenital heart surgery. ( Boom, CE; Busro, PW; Jusuf, AA; Rachmat, J; Romolo, H; Sadikin, M; Santoso, A; Sastroasmoro, S; Suwarto, S, 2018)
"Procaine hydrochloride was added to cardioplegia and studied for its efficacy in stabilizing the postischemic rhythm after aortic declamping in cardiac surgery."	2.68	Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery. ( Berg, EM; Levang, OW; Sellevold, OF, 1995)
"No ventricular arrhythmias were observed after the ICV infusion of saline or with intravenous doses of bupivacaine as large as 1."	1.27	Cardiac dysrhythmias induced by infusion of local anesthetics into the lateral cerebral ventricle of cats. ( Heavner, JE, 1986)
" The dose-response and time-action parameters of the cardiac antiarrhythmic protection afforded by the prototype drugs and their acryloyl derivatives against chloroform-hypoxia-induced cardiac arrhythmias in unanesthetized mice and epinephrine-induced arrhythmias in alpha-chloralose anesthetized cats were determined."	1.27	Prolongation of procaine's and procainamide's actions by binding to acryloyl polymers. ( Baker, T; Erker, EF; Okamoto, M; Riker, WF; Udenfriend, S, 1985)
" Log dose-response curves were plotted for quinidine, papaverine, procaine, dibenamine and procaine amide."	1.24	A comparison of tests for antifibrillatory action. ( SZEKERES, L; WILLIAMS, EM, 1961)

Timeframe	Studies, this research(%)	All Research%
pre-1990	122 (95.31)	18.7374
1990's	3 (2.34)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (2.34)	24.3611
2020's	0 (0.00)	2.80

Article	Year
LOCAL ANESTHETICS. Progress in medicinal chemistry, 1963, Volume: 19 Topics: Analgesia; Anesthetics; Anesthetics, Local; Arrhythmias, Cardiac; Benzoates; Cough; Ethers; Ketones;	1963
Local anesthetic drugs: tissue and systemic toxicity. Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:4 Topics: Anesthesia, Conduction; Anesthetics, Local; Animals; Apnea; Arrhythmias, Cardiac; Barbiturates; Cent	1981
The heart in myasthenia gravis. American heart journal, 1975, Volume: 90, Issue:3 Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans;	1975
Recent advances in local anaesthesia. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Acidosis; Anesthesia, Local; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Bupivacaine; Cardiov	1986
[Treatment of arrhythmia in myocardial infarct]. Kardiologiia, 1968, Volume: 8, Issue:10 Topics: Amides; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Cardiac Complexes, Premature; Cardiac G	1968
The current status of diphenylhydantoin in heart disease. Annals of internal medicine, 1967, Volume: 67, Issue:5 Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiac Surgical Procedures; Car	1967
[Cellular mechanisms of the etiology of cardiac rhythm disturbances and of the action of basic anti-arrhythmia drugs]. Kardiologia polska, 1970, Volume: 13, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biological Transport; Biological Transport, Active; Ce	1970
Adrenaline, digitalis and beta-adrenergic blockade during anaesthesia. South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 1970, Volume: 8, Issue:3 Topics: Acetylcholine; Adenosine Triphosphate; Anesthesia; Animals; Arrhythmias, Cardiac; Atropine; Biologic	1970
The Stokes-Adams syndrome. The American journal of medicine, 1969, Volume: 46, Issue:6 Topics: Adams-Stokes Syndrome; Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Chlorothiazide; Digi	1969

Article	Year
Role of terminal warm blood cardioplegia in complex congenital heart surgery. Asian cardiovascular & thoracic annals, 2018, Volume: 26, Issue:3 Topics: Apoptosis; Arrhythmias, Cardiac; Biomarkers; Cardiac Output, Low; Cardioplegic Solutions; Caspase 3;	2018
Procaine is effective for minimizing postischemic ventricular fibrillation in cardiac surgery. Anesthesia and analgesia, 1995, Volume: 81, Issue:5 Topics: Adult; Aged; Alanine Transaminase; Arrhythmias, Cardiac; Aspartate Aminotransferases; Coronary Arter	1995
Dosage, plasms concentration and antiarrhythmic effect of procainamide in sustained-release tablets. Acta medica Scandinavica, 1974, Volume: 195, Issue:3 Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Delayed-Action Pr	1974

Article	Year
Myocardial protection during minimally invasive cardiac surgery through right mini-thoracotomy. Perfusion, 2017, Volume: 32, Issue:3 Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Transfusion; Cardiac Output, Low; Cardiac Surgical Procedur	2017
Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368. BMC anesthesiology, 2019, 01-08, Volume: 19, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Connexin 43; Disease Models, Animal; Gap Junc	2019
Studies with the polyoxyethylene derivatives of sorbitan partial esters (tweens). Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1 Topics: Anesthesia; Arrhythmias, Cardiac; Esters; Humans; Polyethylene Glycols; Polysorbates; Procaine	1948
Abolition of extra systoles in the perfused isolated rabbit heart by procaine and monocaine hydrochlorides. Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1 Topics: Animals; Arrhythmias, Cardiac; Extracorporeal Circulation; Heart; Procaine; Rabbits; Systole	1948
Effect of procaine on cyclopropane-epinephrine cardiac arrhythmias. Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1 Topics: Anesthesia; Arrhythmias, Cardiac; Cyclopropanes; Epinephrine; Procaine	1948
Treatment of acute arrhythmias during anesthesia by intravenous procaine. Anesthesiology, 1946, Volume: 7 Topics: Anesthesia; Anesthesiology; Arrhythmias, Cardiac; Procaine	1946
The intramuscular use of pronestyl (Procaine amide). The American journal of medicine, 1952, Volume: 13, Issue:2 Topics: Arrhythmias, Cardiac; Injections, Intramuscular; Procainamide; Procaine	1952
[First experiences in novocaine amide therapy of cardiac arrhythmias]. Die Medizinische, 1952, Jul-26, Volume: 31, Issue:29-30 Topics: Amides; Arrhythmias, Cardiac; Procaine	1952
[Procaine and pronestyl administration during anesthesia]. Nederlands tijdschrift voor geneeskunde, 1952, Jun-07, Volume: 96, Issue:23 Topics: Anesthesia; Anesthesiology; Arrhythmias, Cardiac; Procainamide; Procaine	1952
The intramuscular administration of procaine amide; a safe and effective method for the treatment of cardiac arrhythmias. American heart journal, 1952, Volume: 44, Issue:5 Topics: Arrhythmias, Cardiac; Humans; Injections, Intramuscular; Procainamide; Procaine	1952
The response of arrhythmias and tachycardias of supraventricular origin to oral procaine amide. British heart journal, 1952, Volume: 14, Issue:4 Topics: Arrhythmias, Cardiac; Procainamide; Procaine; Tachycardia	1952
Procaine amide in the control of cardiac arrhythmias. British heart journal, 1952, Volume: 14, Issue:4 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
PROCAINE amide. Lancet (London, England), 1952, Nov-22, Volume: 2, Issue:6743 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
Angina pectoris associated with ventricular bigeminy, controlled by procaine amide; report of a case. The New England journal of medicine, 1952, Oct-30, Volume: 247, Issue:18 Topics: Angina Pectoris; Arrhythmias, Cardiac; Humans; Procainamide; Procaine	1952
The treatment of cardiac arrhythmias with procaine amide. Bulletin of the School of Medicine (Baltimore, Md.), 1952, Volume: 37, Issue:4 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
[Digitalis induced premature ventricular extrasystole inhibited by procaine amide]. Archivio per le scienze mediche, 1952, Volume: 94, Issue:4 Topics: Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Plant Extracts; Procainamide; Procaine; Ventr	1952
Arrhythmias produced by intravenous procaine amide. New York state journal of medicine, 1953, Jan-01, Volume: 53, Issue:1 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1953
[Procaine derivative in prophylaxis and therapy of arrhythmias appearing during anesthesia]. La Semana medica, 1952, Oct-23, Volume: 101, Issue:17 Topics: Anesthesia; Anesthesiology; Arrhythmias, Cardiac; Iatrogenic Disease; Procaine	1952
[Comparative tests of novocain, quinidine and strophanthin with respect to excitation and fibrillation of the frog heart]. Zeitschrift fur die gesamte experimentelle Medizin, 1951, Volume: 118, Issue:1 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Conduction S	1951
Atrial conduction disturbance attributed to pronestyl. American heart journal, 1953, Volume: 45, Issue:5 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Heart Atria; Humans; Procainamide; Procaine	1953
[Use of procaine and procaine amide in the treatment of certain arrhythmias]. Revista medica de Chile, 1952, Volume: 80, Issue:11 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
[Procaine amide in certain arrhythmias]. Revista medica de Chile, 1952, Volume: 80, Issue:12 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
Cardiovascular diseases. American practitioner and digest of treatment, 1953, Volume: 4, Issue:5 Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular Sy	1953
The action of procaineamide on fibrillation of the heart. Archives internationales de pharmacodynamie et de therapie, 1953, Volume: 93, Issue:2 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Conduction S	1953
[Effect of procaine amide in disorders due to myocardiac hyperexcitability]. Folia cardiologica, 1953, Volume: 12, Issue:1 Topics: Arrhythmias, Cardiac; Myocardium; Procainamide; Procaine; Psychomotor Agitation	1953
[Experience with procaine amide in arrhythmia therapy]. Nederlands tijdschrift voor geneeskunde, 1953, May-09, Volume: 97, Issue:19 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1953
[Treatment of arrhythmia with procaine amide]. Prensa medica argentina, 1953, May-08, Volume: 40, Issue:19 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1953
[Autonomic block with novocaine and novocaine amide; prevention and therapy of cardiac arrhythmia during narcosis]. Thoraxchirurgie, 1953, Volume: 1, Issue:3 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;	1953
[Experiences with novocaine and novocaine amide in rhythmic disorders during thoracic surgery]. Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1953, Volume: 276 Topics: Amides; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Physiological Phenomena; Procaine; Thorac	1953
Influence of antiarrhythmic agents on calcium-induced cardiac arrhythmias in the rat. Circulation research, 1955, Volume: 3, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiovascular Agents; Procaine; Qui	1955
The initiation of ventricular tachycardia and fibrillation by procaine in the isolated-perfused rabbit heart. Circulation research, 1956, Volume: 4, Issue:1 Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction	1956
[Defibrillatory effect of several substituted derivatives of phenoxyacetic acid]. Il Farmaco; edizione scientifica, 1955, Volume: 10, Issue:11 Topics: Acetates; Arrhythmias, Cardiac; Cardiovascular Diseases; Procainamide; Procaine; Ventricular Fibrill	1955
[Anti-fibrillation substances]. Medicina interna, 1956, Volume: 8, Issue:7 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Cinc	1956
[Restoration of a disturbed cardiac rhythm with the influence of a procaine block extracardial nerve formations and some other interventions of the nervous system]. Biulleten' eksperimental'noi biologii i meditsiny, 1957, Volume: 43, Issue:1,Suppl Topics: Arrhythmias, Cardiac; Humans; Nerve Block; Nervous System; Procaine	1957
[Control of rhythmic disorders in cardiac catheterization by causat]. Therapie der Gegenwart, 1957, Volume: 96, Issue:6 Topics: Arrhythmias, Cardiac; Atropine; Cardiac Catheterization; Catheterization; Heart Diseases; Niacin; Ni	1957
[Use of novocaine-amide (procaine-amide) in various disorders of the cardiac rhythm]. Klinicheskaia meditsina, 1957, Volume: 35, Issue:8 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1957
[Change in the fibrillation threshold of auricular and ventricular musculature of isolated mammalian heart after cooling and after administration of various pharmacological agents]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1960, Volume: 238 Topics: Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart; Heart Con	1960
[Acute disorders of the ventricular rhythm of the heart as terminal disorders and some possibilities for their treatment]. Terapevticheskii arkhiv, 1962, Volume: 34 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Camphor; Cardiac Conduction System Disease; Coronary Disease	1962
[Use of novocaine amide in the permanent form of cardiac fibrillation]. Zdravookhranenie Belorussii, 1963, Volume: 9 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Hear	1963
A comparison of tests for antifibrillatory action. British journal of pharmacology and chemotherapy, 1961, Volume: 17 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Complexes, Prematur	1961
ACONITE POISONING AND CARDIAC ARRHYTHMIAS: REPORT OF 3 CASES. Indian journal of medical sciences, 1963, Volume: 17 Topics: Aconitum; Arrhythmias, Cardiac; Electrocardiography; Humans; Procaine; Toxicology	1963
ELECTROCARDIOGRAPHY DURING POSTERIOR FOSSA OPERATIONS. British journal of anaesthesia, 1964, Volume: 36 Topics: Arrhythmias, Cardiac; Electrocardiography; Embolism; Embolism, Air; Humans; Hypotension; Infant; Lid	1964
[SOME NEW DRUGS IN THE TREATMENT OF RHEUMATIC CHILDREN]. Pediatriia, 1964, Volume: 43 Topics: Adolescent; Alkaloids; Anabolic Agents; Antithyroid Agents; Arrhythmias, Cardiac; Cardiovascular Dis	1964
DRUG TREATMENT OF CARDIAC ARRHYTHMIAS. The American journal of nursing, 1964, Volume: 64 Topics: Arrhythmias, Cardiac; Atropine; Digitalis Glycosides; Drug Therapy; Humans; Isoproterenol; Lanatosid	1964
DRUGS FOR ARRHYTHMIAS. Canadian Medical Association journal, 1964, Jun-13, Volume: 90 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Digoxin; Drug Thera	1964
[ON EXCITABILITY OF THE VAGO-SYMPATHETIC NERVOUS SYSTEM IN RADIATION INJURY]. Meditsinskaia radiologiia, 1964, Volume: 9 Topics: Animals; Arrhythmias, Cardiac; Atropine; Autonomic Nerve Block; Electrocardiography; Humans; Procain	1964
[COUNTEREFFECT OF LOCAL BLOCKING AGENTS ON CARDIAC ARRHYTHMIA]. Zahnarztliche Welt, zahnarztliche Reform, ZWR, 1965, Jan-10, Volume: 66 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Complexes, Premature; Cardiac Conduction System Dise	1965
THE RESPIRATORY FACTOR IN ANGIOGRAPHIC MEDIA TOXICITY. Radiology, 1965, Volume: 84 Topics: Angiography; Animals; Apnea; Arrhythmias, Cardiac; Atropine; Blood Pressure; Contrast Media; Dextran	1965
Some common cardiac arrhythmias. Journal of the Medical Association of Georgia, 1955, Volume: 44, Issue:3 Topics: Arrhythmias, Cardiac; Procaine; Quinidine	1955
Procaine amide (pronestyl) in the treatment of disorders of cardiac rhythm. The Journal of the Kentucky State Medical Association, 1950, Volume: 48, Issue:11 Topics: Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Procainamide; Procaine	1950
[Procaine-amide (pronestyl) and cardiac arrhythmias during heart catheterization]. Acta cardiologica, 1951, Volume: 6, Issue:1 Topics: Arrhythmias, Cardiac; Cardiac Catheterization; Heart; Procainamide; Procaine	1951
[Pharmacology of aconitine-induced fibrillation of the isolated mammalian heart]. Archives internationales de pharmacodynamie et de therapie, 1951, Volume: 85, Issue:1-2 Topics: Aconitine; Animals; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart	1951
Use of procaine amide in cardiac arrhythmias. Modern concepts of cardiovascular disease, 1951, Volume: 20, Issue:6 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1951
Effects of procaine amide on cardiac irregularities during cyclopropane anesthesia. Anesthesiology, 1951, Volume: 12, Issue:3 Topics: Anesthesia; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Cyclopropanes	1951
The action of procaine amide in cardiac arrhythmias. Journal of the American Medical Association, 1951, Jul-14, Volume: 146, Issue:11 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1951
[Novocaine and cardiac arrhythmias; preliminary note]. Archivos del Instituto de Cardiologia de Mexico, 1951, Volume: 21, Issue:1 Topics: Arrhythmias, Cardiac; Procaine	1951
The use of procaine amide in cardiac arrhythmias. Circulation, 1951, Volume: 4, Issue:1 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1951
Ventricular tachycardia; report of a case in which "pronestyl" was effectively used after failure with quinidine. Journal of the American Medical Association, 1951, Aug-04, Volume: 146, Issue:14 Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Procainamide; Procaine; Quinidine; Tachycardia, Ventr	1951
Procaine amide for prophylaxis and therapy of cardiac arrhythmias occurring during thoracic surgery. Surgery, gynecology & obstetrics, 1951, Volume: 93, Issue:1 Topics: Arrhythmias, Cardiac; Procainamide; Procaine; Thoracic Surgery; Thoracic Surgical Procedures; Thorax	1951
Clinical use of procaine amide (pronestyl) during anesthesia. New York state journal of medicine, 1951, Aug-01, Volume: 51, Issue:15 Topics: Anesthesia; Anesthesiology; Arrhythmias, Cardiac; Procainamide; Procaine	1951
[Comparison of effects of quinidine and procaine amide (pronestyl) in a case of ventricular tachycardia]. Prensa medica argentina, 1951, Aug-03, Volume: 38, Issue:31 Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Procainamide; Procaine; Quinidine; Tachycardia, Ventr	1951
A study of the effect of procaine amide hydrochloride in supraventricular arrhythmias. Circulation, 1951, Volume: 4, Issue:3 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Disease; Hear	1951
Procaine amide compared with quinidine as a therapy for arrhythmias. American heart journal, 1951, Volume: 42, Issue:4 Topics: Arrhythmias, Cardiac; Humans; Procainamide; Procaine; Quinacrine; Quinidine	1951
[Procaine amide in the treatment of ventricular paroxysmal tachycardia and other disorders of cardiac rhythm]. Archives des maladies du coeur et des vaisseaux, 1951, Volume: 44, Issue:8 Topics: Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Humans; Procainamide; Procaine; Tachyc	1951
Procaine amide (pronestyl) in the treatment of cardiac arrhythmias. Transactions of the Association of American Physicians, 1951, Volume: 64 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1951
Procaine amide (pronestyl) in the treatment of cardiac arrhythmias. The American journal of the medical sciences, 1951, Volume: 222, Issue:4 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1951
Use of pronestyl in the treatment of ectopic rhythms; treatment of 98 episodes in 78 patients. The American journal of medicine, 1951, Volume: 11, Issue:4 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;	1951
[New procaine derivative in the therapy of cardiac arrhythmias: pronestyl]. Medecine et hygiene, 1952, Jan-01, Volume: 10, Issue:209 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
[Effect of procaine amide (pronestyl) on the heart; experimental study on the effect of associated digitalis and procaine amide]. Archivos del Instituto de Cardiologia de Mexico, 1951, Volume: 21, Issue:5-6 Topics: Arrhythmias, Cardiac; Digitalis; Digitalis Glycosides; Drug-Related Side Effects and Adverse Reactio	1951
[Effect of procaine amide (pronestyl) on the heart; clinical study]. Archivos del Instituto de Cardiologia de Mexico, 1951, Volume: 21, Issue:5-6 Topics: Arrhythmias, Cardiac; Biomedical Research; Heart; Procainamide; Procaine	1951
[Observations on oral use of pronestyl]. Nederlands tijdschrift voor geneeskunde, 1951, Dec-01, Volume: 95, Issue:48 Topics: Administration, Oral; Arrhythmias, Cardiac; Procainamide; Procaine	1951
Effect of procaine amide on anomalous conduction and paroxysmal tachycardia in a case resembling the Wolff-Parkinson-White syndrome. American heart journal, 1952, Volume: 44, Issue:1 Topics: Arrhythmias, Cardiac; Humans; Procainamide; Procaine; Tachycardia; Tachycardia, Paroxysmal; Wolff-Pa	1952
The effect of procaine amide (pronestyl) in clinical auricular fibrillation and flutter. Circulation, 1952, Volume: 6, Issue:1 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Humans; Procainamide; Procaine	1952
[Experimental study on pharmaco-biological activity of procaine amide hydrochloride]. Archivio italiano di scienze farmacologiche, 1952, Volume: 2, Issue:2 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
[Action of procaine amide on alternations in cardiac contractility]. Acta cardiologica, 1952, Volume: 7, Issue:3 Topics: Arrhythmias, Cardiac; Heart; Heart Rate; Procainamide; Procaine; Pulse	1952
[Procaine amide and toxic ventricular estrasystolies]. Archives internationales de pharmacodynamie et de therapie, 1952, Volume: 89, Issue:4 Topics: Arrhythmias, Cardiac; Heart Ventricles; Procainamide; Procaine	1952
[Procaine amide in cardiac arrhythmias]. Arquivos brasileiros de cardiologia, 1952, Volume: 5, Issue:1 Topics: Arrhythmias, Cardiac; Procainamide; Procaine	1952
[Procaine amide therapy of extra-systolic ventricular arrhythmia]. Concours medical, 1952, Mar-01, Volume: 74, Issue:9 Topics: Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System;	1952
Intravenous procaine; its effect on the human electrocardiogram and on cardiac arrhythmias. Cardiologia, 1950, Volume: 16, Issue:5-6 Topics: Arrhythmias, Cardiac; Electrocardiography; Heart; Procaine	1950
CARDIAC SLOWING DURING STRABISMUS SURGERY. The British journal of ophthalmology, 1962, Volume: 46, Issue:2 Topics: Adolescent; Anesthetics, Local; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Electrocard	1962
[Complications during novocaine treatmetn of patients with disorders of the heart rhythm]. Vrachebnoe delo, 1966, Volume: 11 Topics: Arrhythmias, Cardiac; Female; Heart Conduction System; Humans; Middle Aged; Procaine	1966
[Cardiac action of crystalline tetrodotoxin. 3. Effects on the extension of non-reacting period of the isolated atria]. Igaku to seibutsugaku. Medicine and biology, 1967, Jan-10, Volume: 74, Issue:1 Topics: Animals; Arrhythmias, Cardiac; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; In Vitro Techn	1967
[Effects of ouabain on the isolated guinea-pig atria pretreated by reserpine and under the influence of propranolol administration]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1967, Jul-20, Volume: 63, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Muscle Con	1967
[Local anesthetic intoxication manifested in ECG abnormality during general anesthesia in infants]. Masui. The Japanese journal of anesthesiology, 1982, Volume: 31, Issue:7 Topics: Anesthesia, General; Anesthetics, Local; Arrhythmias, Cardiac; Child, Preschool; Electrocardiography	1982
[Complications after intravenous administration of anti-arrhythmia agents]. Kardiologiia, 1982, Volume: 22, Issue:11 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Ad	1982
Comparison of UW versus HTK solution for myocardial protection in heart transplantation. Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1 Topics: Adenosine; Allopurinol; Arrhythmias, Cardiac; Chi-Square Distribution; Female; Glucose; Glutathione;	1994
Reappraisal of intravenous procaine as a short-acting anesthetic adjuvant. American journal of surgery, 1979, Volume: 138, Issue:6 Topics: Adolescent; Adult; Anesthetics; Arrhythmias, Cardiac; Blood Gas Analysis; Bronchoscopy; Child; Cough	1979
Effect of lorcainide, a new antiarrhythmic compound, on the changes in heart rhythm induced by intravenous injection of adenosine-5'-diphosphate in rats. Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 231, Issue:2 Topics: Acetamides; Adenosine Diphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac;	1978
Adverse reactions to commonly prescribed drugs in patients with renal insufficiency. Journal of the Tennessee Medical Association, 1977, Volume: 70, Issue:8 Topics: Analgesics; Anti-Bacterial Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Drug-Related Side	1977
Further observations on the antimicrobial effects of local anesthetic agents. Current therapeutic research, clinical and experimental, 1975, Volume: 17, Issue:4 Topics: Anesthetics, Local; Arrhythmias, Cardiac; Bacteria; Benzoates; Candida albicans; Cyclohexylamines; E	1975
[Heart rhythm disorders and bases of its therapy]. Voenno-meditsinskii zhurnal, 1977, Issue:3 Topics: Ajmaline; Arrhythmias, Cardiac; Humans; Lidocaine; Procaine; Quinidine; Tachycardia	1977
Reperfusion arrhythmias after cardioplegia using Bretschneider-HTK solution. The Thoracic and cardiovascular surgeon, 1990, Volume: 38, Issue:6 Topics: Arrhythmias, Cardiac; Cardioplegic Solutions; Glucose; Heart Arrest, Induced; Humans; Hypertonic Sol	1990
Anaesthesia for caesarean section in a patient with Jervell, Lange-Nielsen syndrome. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:4 Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Arrhythmias, Cardiac; Cesarean Section; Female	1988
Cardiac dysrhythmias induced by infusion of local anesthetics into the lateral cerebral ventricle of cats. Anesthesia and analgesia, 1986, Volume: 65, Issue:2 Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Blood Pressure; Brain; Bupivacaine; Cats; Heart R	1986
Differences in electrical and mechanical recovery from ischemic heart arrest and cardioplegia. Advances in myocardiology, 1985, Volume: 6 Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Electrocardiography; Heart Ar	1985
Prolongation of procaine's and procainamide's actions by binding to acryloyl polymers. European journal of pharmacology, 1985, Aug-27, Volume: 114, Issue:3 Topics: Acrylic Resins; Animals; Arrhythmias, Cardiac; Cats; Dose-Response Relationship, Drug; Female; Kinet	1985
[Clinical significance and treatment of disorders of the cardiac rhythm in patients with myocardial infarct]. Kardiologiia, 1969, Volume: 9, Issue:1 Topics: Adult; Aged; Amides; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, P	1969
[Combination of cardioplegia and coronary perfusion in heart surgery under normothermia]. Thoraxchirurgie, vaskulare Chirurgie, 1972, Volume: 20, Issue:6 Topics: Aortic Valve; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiomegaly; Coronary Vessels; Hea	1972
Studies on the cardiotoxicity of ouabain. Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:2 Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Atropine; Bretylium Compounds; Cats; Epinephrine; Etha	1969
The influence of pharmacological blockade of presynaptic and postsynaptic adrenergic structures on electrically induced arrhythmias of the guinea-pig atria. Folia biologica, 1969, Volume: 17, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Depression, Chemical; Guanethidine; Guan	1969
Local anaesthetic and anti-arrhythmic actions of alprenolol relative to its effect on intracellular potentials and other properties of isolated cardiac muscle. British journal of pharmacology, 1970, Volume: 38, Issue:4 Topics: Action Potentials; Adrenergic beta-Antagonists; Amino Alcohols; Anesthesia, Local; Anesthetics, Loca	1970
The reversal of experimental cardiac arrhythmias by indoramin (Wy 21901). The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:9 Topics: Amides; Anesthetics, Local; Animals; Arrhythmia, Sinus; Arrhythmias, Cardiac; Blood Pressure; Cats;	1971
Antiarrhythmic activity of 1-(7-indenyloxy)-3-isopropylaminopropane-2-ol hydrochloride (YB-2) and its optical isomers. Japanese journal of pharmacology, 1974, Volume: 24, Issue:4 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chloroform; Depression, C	1974
Effects of cyclopropane on the sympathetic nervous system and on neural regulation of circulation in the cat. Anesthesiology, 1974, Volume: 40, Issue:4 Topics: Action Potentials; Animals; Aorta; Arrhythmias, Cardiac; Blood; Blood Circulation; Blood Pressure; B	1974
[Antiarrhythmic effect of some local anesthetics]. Bollettino chimico farmaceutico, 1972, Volume: 111, Issue:5 Topics: Anesthetics, Local; Animals; Arrhythmias, Cardiac; Cats; Lidocaine; Procaine; Rats; Tetracaine	1972
Cardiac excitability in the course of radiation disease. II. Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1966, Volume: 9, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Heart; Procaine; Rabbits; Radiation Injuries, Experimental	1966
Effect of local anesthetic agents on the arrhythmias of the isolated rabbit heart. Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1971, Aug-28, Volume: 70, Issue:8 Topics: Aconitine; Aminobenzoates; Anesthetics, Local; Animals; Arrhythmias, Cardiac; Heart; In Vitro Techni	1971
The effect of bretylium on intracellular cardiac action potentials in relation to its anti-arrhythmic and local anaesthetic activity. British journal of pharmacology, 1969, Volume: 37, Issue:2 Topics: Action Potentials; Anesthetics, Local; Animals; Anura; Arrhythmias, Cardiac; Bretylium Compounds; Gu	1969
Effect of various antiarrhythmic drugs on the daunomycin-induced arrhythmia in the hamster. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:1 Topics: Amino Alcohols; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cri	1970
[Treatment of imipramine poisoning at childhood]. Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:11 Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot	1970
[Effect of novocaine administered intraperitoneally on the cardiovascular system in the postoperative period]. Klinicheskaia khirurgiia, 1970, Volume: 9 Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Injections, Intraperitoneal; Male; Postoperative Complic	1970
[Death and resuscitation in drowning]. Minerva anestesiologica, 1970, Volume: 36, Issue:7 Topics: Animals; Anticoagulants; Arrhythmias, Cardiac; Assisted Circulation; Blood Transfusion; Brain Death;	1970
[Treatment of the most severe postoperative cardiac arrhythmias]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1970, Volume: 51, Issue:8 Topics: Aged; Arrhythmias, Cardiac; Bradycardia; Digitoxin; Electrocardiography; Female; Humans; Lidocaine;	1970
Effects of intracerebroventricular l-hyoscyamine, ethybenztropine and procaine on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside. International journal of neuropharmacology, 1968, Volume: 7, Issue:1 Topics: Animals; Arrhythmias, Cardiac; Atropa belladonna; Bradycardia; Carotid Artery Thrombosis; Central Ne	1968
Passage of procaine hydrochloride and para-aminobenzoic acid across the human placenta. American journal of obstetrics and gynecology, 1968, Volume: 100, Issue:7 Topics: Adjuvants, Anesthesia; Aminobenzoates; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics,	1968
Study on the effect of a beta-adrenolytic agent upon thiobarbiturate-arrhythmia in the dog. Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 162, Issue:1 Topics: Animals; Arrhythmias, Cardiac; Barbiturates; Dogs; Electrocardiography; Lidocaine; Procaine; Propran	1966

procaine and Arrhythmias, Cardiac

Research Excerpts

Research

Studies (128)

Authors

Reviews

Trials

Other Studies

Authors	Studies
De Palo, M	1
Guida, P	1
Mastro, F	1
Nanna, D	1
Quagliara, TA	1
Rociola, R	1
Lionetti, G	1
Paparella, D	1
Busro, PW	1
Romolo, H	1
Sastroasmoro, S	1
Rachmat, J	1
Sadikin, M	1
Santoso, A	1
Boom, CE	1
Suwarto, S	1
Jusuf, AA	1
Li, WC	1
Gao, H	1
Gao, J	1
Wang, ZJ	1
MUSSER, R	1
PRATT, HJ	1
NICKERSON, M	1
BURSTEIN, C	1
BELLET, S	2
ZEEMAN, SE	1
HIRSH, SA	1
ZEH, E	1
BOERE, LA	1
ENSELBERG, CD	1
LIPKIN, M	1
SCHACK, JA	1
HOFFMAN, I	2
VESELL, H	1
LUCAS, BG	1
SHORT, DS	1
DAVIS, D	1
SWISHER, KY	1
EBELING, WC	1
MARTELLI, A	1
ACIERNO, LJ	1
GUBNER, R	1
POLIAKOFF, B	1
CABO, HA	1
WENDHUT, G	1
LENDLE, L	1
WALTERS, JH	1
POTASHNICK, R	1
AHUMADA, J	1
NIEDMANN, L	1
MORDOH, I	1
BEREGOVICH, J	1
SAN-CRISTOBAL, D	1
SEPULVEDA, G	1
KERR, WJ	1
LAGEN, JB	1
VAN DONGEN, K	1
TESTONI, F	1
TOMMASELLI, A	1
VISSER, JF	1
VAN SCHOTHORST, HK	1
VEDOYA, R	2
COPELLO, CE	1
NESSI, CT	1
MENDELZON, J	1
ZURN, L	2
WINBURY, MM	1
HEMMER, ML	1
GRUMBACH, L	1
CAVALLINI, G	1
MILLA, E	1
RAVENNA, F	1
GRUMELLI, E	1
GHEORGHIU, P	1
STROESCU, V	1
FEDOROV, BM	1
MICHEL, D	1
BOCK, K	1
HARTLEB, O	1
HERBST, M	1
KRASOVSKII, II	1
SZEKERES, L	2
LENARD, G	1
LESIUIS, Ie	1
ROZIN, MZ	1
WILLIAMS, EM	2
MERCHANT, HC	1
CHOKSI, ND	1
RAMAMOORTHY, K	1
PARIHAR, LM	1
SHIKARIPURKAR, NK	1
LEWIS, JM	1
REES, GA	1
WIEDLING, S	1
TEGNER, C	1
SOKOLOV-PONOMAREVA, OD	1
BEREZHKOV, LF	1
BERNSTEIN, H	1
GUNTON, RW	1
JURKOVIC, V	2
VOKROUHLICKY, L	2
NAVARIVERA, A	1
VEGAESQUIVEL, E	1
LOPEZ, AJ	1
BERNSTEIN, EF	1
BROWN, CE	1
KINSMAN, JM	3
CLAY, HL	2
COE, WS	2
BEST, MM	2
van den HEUVEL-HEYMANS, G	1
TRIPOD, J	1
KAYDEN, HJ	3
BRODIE, BB	2
STEELE, JM	2
MORRIS, LE	1
HAID, B	1
MILLER, H	1
NATHANSON, MH	1
GRIFFITH, GC	1
ZAPATA DIAZ, J	3
FERNANDEZ CAMINERO, J	1
CAHEN, P	1
MENDOZA, F	1
MARK, LC	1
IRVIN, CW	1
CUTTS, FB	1
JOSEPH, SI	2
HELRICH, M	1
ORKIN, LR	2
ROVENSTINE, EA	2
GARIBOTTO, RC	1
CULOGA, AP	1
McCORD, MC	1
TAGUCHI, JT	1
SCHAFFER, AI	2
SIGUIER, F	1
WELTI, JJ	1
HANSEN, WR	1
McCLENDON, RL	1
BERRY, K	1
GARLETT, EL	1
GEFTER, WI	1
RENTCHNICK, P	1
CABRERA, E	2
MENDEZ, R	1
BURKENS, JC	1
ABERNATHY, RS	1
HAEDICKE, TA	1
MILLER, G	1
WEINBERG, SL	1
PICK, A	1
MARCHETTI, G	1
CLOETENS, W	1
CHARLIER, R	1
MURGEL, L	1
REGALLA, J	1
COMISIONERU, N	1
STEINMAN, R	1
SCHERF, D	1
Reed, H	1
McCaughey, T	1
Bugaeva, VI	1
Pliska, GD	1
Ogura, Y	1
Mizukami, K	1
Maeda, K	1
Moore, DC	1
Yamaoka, H	1
Tomemori, N	1
Kuba, Y	1
Fukutake, Y	1
Anshelevich, IuV	1
Dumesh, SZ	1
Slaĭdyn', AK	1
Sporan, VG	1
Sellevold, OF	1
Berg, EM	1
Levang, OW	1
Reichenspurner, H	1
Russ, C	1
Wagner, F	1
Uberfuhr, P	1
Nollert, G	1
Weinhold, C	1
Reichart, B	1
Thompson, DS	1
Seifen, AB	1
Ferrari, AA	1
Lawson, NW	1
De Clerck, F	1
Van Gorp, L	1
Xhonneux, R	1
McAllister, CJ	1
Weinstein, MP	1
Maderazo, E	1
Tilton, R	1
Maggini, G	1
Quintiliani, R	1
Semenko, AN	1
Krylov, AA	1
Gibson, TC	1
Panzner, R	1
Wollert, HG	1
Hermann, M	1
Taha, M	1
Schischka, F	1
Ryan, H	1
Covino, BG	1
Heavner, JE	1
Juggi, JS	1
Braveny, P	1
Telahoun, G	1
Shuhaiber, HJ	1
Yousof, AM	1
Erker, EF	1
Baker, T	1
Okamoto, M	1
Udenfriend, S	1
Riker, WF	1
Chazov, EI	1
Lukomskiĭ, PE	1
Doshchitsin, VL	1
Kalmar, P	1
Bleese, N	1
Kirsch, U	1
Lutz, G	1
Pokar, H	1
Rodewald, G	1
Reynolds, AK	1
Horne, ML	1
Grodzińska, L	1
Singh, BN	1
Alps, BJ	1
Hill, M	1
Fidler, K	1
Johnson, ES	1
Wilson, AB	1
Kato, H	1
Noguchi, Y	1
Takagi, K	1
Arstila, M	1
Katila, M	1
Sundquist, H	1
Anttila, M	1
Pere, E	1
Tikkanen, R	1
Fukunaga, AF	1
Epstein, RM	1
Mercer, EN	1
Osborne, JA	1
Lewartowski, B	1
Kwiatkowska, B	1
Vetten, KB	1
Pomerantz, B	1
O'Rourke, RA	1
Ferrero, E	1
Manzoni, L	1
Lin, MK	1
Huang, TF	1
Papp, JG	1
Vaughan Williams, EM	1
Herman, EH	1
Schein, P	1
Taylor, O	1
Waravdekar, VS	1
Bartelheimer, HK	1
Bauditz, W	1
Zhitniuk, RI	1
Mitropol'skiĭ, AN	1
Manni, C	1
Mazzoni, P	1
Staffen, A	1
Wolner, E	1
Rozear, M	1
Bircher, RP	1
Chai, CY	1
Wang, SC	1
Usubiaga, JE	1
La Iuppa, M	1
Moya, F	1
Wikinski, JA	1
Velazco, R	1
Frey, HH	1
Nielsen, CK	1