Compounds > procaine
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procaine and Anesthesia Related Hyperthermia

procaine has been researched along with Anesthesia Related Hyperthermia in 41 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Research Excerpts

ExcerptRelevanceReference
" Using muscle from patients susceptible to malignant hyperpyrexia in vitro, it has been demonstrated that muscle contracture can occur with procaine on its own, and in one patient the halothane-induced contracture was potentiated by procaine."3.65An evaluation of procaine in the treatment of malignant hyperpyrexia. ( Clarke, IM; Ellis, FR, 1975)
"Malignant hyperpyrexia is a genetically related syndrome that cannot be predicted reliably in advance of administration of anesthesia except by a strong family history."2.36Malignant hyperpyrexia. ( Stephen, CR, 1977)
"Two myopathies predisposing to malignant hyperpyrexia have been identified."2.35Malignant hyperpyrexia. ( Denborough, MA, 1975)
"At that time malignant hyperthermia developed."1.28[The anesthetic management of a patient with the malignant hyperthermia trait diagnosed preoperatively]. ( Fujiwara, K; Nomiyama, S; Okada, S; Takenaka, T; Tanaka, R; Watanabe, S, 1991)
"This situation may be similar to that in malignant hyperpyrexia (MH) occurring in mammals."1.26The chick as a model for malignant hyperpyrexia. ( Korczyn, AD; Shavit, S; Shlosberg, I, 1980)
"An exceptionally serious case of malignant hyperthermia in a 17 year old male is presented."1.26[Malignant hyperthermia. A case report (author's transl)]. ( Rettig, B; Weitz, H, 1980)
"A case of malignant hyperthermia with muscle stiffness is described."1.26[Malignant hyperthermia. Report on a case successfully treated by procaine infusion (author's transl)]. ( Bentia, L; Ghiga, R; Litarczek, G, 1978)
"The coincidence of malignant hyperthermia in a patient with such a rare syndrome points to the excessive formation of androgens in patients with this syndrome as a predisposing factor."1.26Ten cases of malignant hyperthermia in Norway. ( Holen, A; Innes, KR; Stovner, J, 1976)
"Many cases of malignant hyperthermia can be prevented if an adequate history is obtained."1.25Malignant hyperthermia. ( Gracia, RM; Schwartz, HC, 1975)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199040 (97.56)18.7374
1990's1 (2.44)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khalil, SN1
Williams, JP1
Bourke, DL1
Hall, GM4
Lucke, JN3
Lister, D4
Denborough, MA5
Korczyn, AD1
Shavit, S1
Shlosberg, I1
Rettig, B1
Weitz, H1
Gronert, GA1
Milde, JH1
Theye, RA1
Höivik, B2
Stovner, J3
Campion, DR1
Topel, DG1
Mitchell, G2
Heffron, JJ2
Stephen, CR1
Freitag, B1
Youngberg, JA1
Litarczek, G1
Bentia, L1
Ghiga, R1
Austin, KL1
Innes, KR1
Holen, A1
Borden, H1
Hummer, GJ1
Landon, CW1
Paris, J1
Schwartz, HC1
Gracia, RM1
Clarke, IM3
Ellis, FR5
Saviello, GM1
Fujiwara, K1
Takenaka, T1
Okada, S1
Nomiyama, S1
Watanabe, S1
Tanaka, R1
Jacquot, C1
Alibeu, JP1
Gelas, P1
Stieglitz, P1
Kiwitt, A1
Pingel, E1
MacLachlan, D1
Forrest, AL1
Britt, BA2
Purschke, R1
Zindler, M1
Relton, JE1
Steward, DJ1
Moulds, RF2
Keaney, NP1
Harriman, DG1
Bull, AB1
Harrison, GG1
Benumof, J1

Reviews

8 reviews available for procaine and Anesthesia Related Hyperthermia

ArticleYear
Malignant hyperthermia--pearls out of swine?
    British journal of anaesthesia, 1980, Volume: 52, Issue:2

    Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Halothane; Magnesium Sulfate; Maligna

1980
The pathopharmacology of malignant hyperpyrexia.
    Pharmacology & therapeutics, 1980, Volume: 9, Issue:3

    Topics: Adenylate Kinase; Anesthesia, General; Animals; Blood Platelets; Calcium; Catecholamines; Cats; Dant

1980
A review of the role of swine skeletal muscle in malignant hyperthermia.
    Journal of animal science, 1975, Volume: 41, Issue:3

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anura; Calcium; Dogs; Glycolysis; Haloth

1975
Treatment of porcine malignant hyperthermia. A review based on experimental studies.
    Anaesthesia, 1975, Volume: 30, Issue:3

    Topics: Animals; Blood Glucose; Body Temperature; Carbon Dioxide; Catecholamines; Chlorpromazine; Dantrolene

1975
Anaesthesia of pigs sensitive to malignant hyperthermia.
    The Veterinary record, 1977, Jan-15, Volume: 100, Issue:3

    Topics: Anesthesia; Animals; Barbiturates; Body Temperature; Cardiac Output; Dantrolene; Halothane; Heart Ra

1977
Malignant hyperpyrexia.
    Annual review of medicine, 1977, Volume: 28

    Topics: Acute Kidney Injury; Adenosine Triphosphate; Anesthetics; Bicarbonates; Body Temperature; Calcium; C

1977
Malignant hyperpyrexia.
    Comprehensive therapy, 1975, Volume: 1, Issue:8

    Topics: Adenosine Triphosphate; Anesthesia, General; Animals; Calcium; Cold Temperature; Creatine Kinase; Hu

1975
Malignant hyperpyrexia.
    British journal of anaesthesia, 1973, Volume: 45, Issue:3

    Topics: Adenosine Triphosphate; Anesthesia, General; Animals; Bicarbonates; Caffeine; Creatine Kinase; Glyco

1973

Other Studies

33 other studies available for procaine and Anesthesia Related Hyperthermia

ArticleYear
Management of a malignant hyperthermia susceptible patient in labor with 2-chloroprocaine epidural anesthesia.
    Anesthesia and analgesia, 1983, Volume: 62, Issue:1

    Topics: Adolescent; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Gas Analysis; Enzymes; Female; Huma

1983
The chick as a model for malignant hyperpyrexia.
    European journal of pharmacology, 1980, Jan-25, Volume: 61, Issue:2

    Topics: Animals; Calcium; Chickens; Dantrolene; Disease Models, Animal; Drug Evaluation, Preclinical; Malign

1980
[Malignant hyperthermia. A case report (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:2

    Topics: Adolescent; Halothane; Heart Arrest; Hemorrhagic Disorders; Humans; Ice; Male; Malignant Hyperthermi

1980
Porcine malignant hyperthermia induced by halothane and succinylcholine: failure of treatment with procaine or procainamide.
    Anesthesiology, 1976, Volume: 44, Issue:2

    Topics: Animals; Catecholamines; Halothane; Hydrogen-Ion Concentration; Lactates; Malignant Hyperthermia; Po

1976
Letter: Procaine and malignant hyperthermia.
    Lancet (London, England), 1975, Jul-26, Volume: 2, Issue:7926

    Topics: Adolescent; Humans; Infusions, Parenteral; Male; Malignant Hyperthermia; Procaine; Time Factors

1975
Procaine in porcine malignant hyperthermia.
    British journal of anaesthesia, 1975, Volume: 47, Issue:6

    Topics: Animals; Body Temperature; Creatine Kinase; Halothane; Hydrogen-Ion Concentration; Injections, Intra

1975
[Malignant hyperthermia: clinical aspects and treatment (author's transl)].
    Zentralblatt fur Chirurgie, 1979, Volume: 104, Issue:6

    Topics: Anesthesia, Inhalation; Anesthesia, Local; Humans; Malignant Hyperthermia; Procaine; Surgical Proced

1979
Anesthetic management of a pregnant patient with malignant hyperpyrexia susceptibility.
    Journal of the Medical Association of Georgia, 1979, Volume: 68, Issue:12

    Topics: Adult; Anesthesia, Epidural; Female; Humans; Malignant Hyperthermia; Obstetric Labor Complications;

1979
[Malignant hyperthermia. Report on a case successfully treated by procaine infusion (author's transl)].
    Der Anaesthesist, 1978, Volume: 27, Issue:12

    Topics: Adult; Female; Humans; Infusions, Parenteral; Malignant Hyperthermia; Muscle Rigidity; Pregnancy; Pr

1978
Drug treatment of malignant hyperpyrexia.
    Anaesthesia and intensive care, 1977, Volume: 5, Issue:3

    Topics: Caffeine; Calcium; Dantrolene; Humans; Hydantoins; Malignant Hyperthermia; Muscle Contraction; Muscl

1977
Ten cases of malignant hyperthermia in Norway.
    Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Age Factors; Anesthesia, General; Animals; Child; Creatine Kinase; Female; Humans

1976
The use of procaine in acquired malignant hyperthermia in a patient with malignant melanoma metastatic to the parathyroid gland: a case report.
    Canadian Anaesthetists' Society journal, 1976, Volume: 23, Issue:6

    Topics: Humans; Male; Malignant Hyperthermia; Melanoma; Middle Aged; Neoplasm Metastasis; Parathyroid Glands

1976
Malignant hyperthermia.
    Journal of oral surgery (American Dental Association : 1965), 1975, Volume: 33, Issue:1

    Topics: Adolescent; Anesthetics; Calcium; Child; Female; Humans; Male; Malignant Hyperthermia; Muscle Relaxa

1975
Letter: Procaine for malignant hyperthermia.
    The New England journal of medicine, 1975, Jan-30, Volume: 292, Issue:5

    Topics: Animals; Calcium; Disease Models, Animal; Halothane; Humans; Malignant Hyperthermia; Procaine; Sarco

1975
An evaluation of procaine in the treatment of malignant hyperpyrexia.
    British journal of anaesthesia, 1975, Volume: 47, Issue:1

    Topics: Anesthesia, General; Animals; Caffeine; Contracture; Dose-Response Relationship, Drug; Drug Evaluati

1975
Drug fever.
    The Medical letter on drugs and therapeutics, 1975, Jul-18, Volume: 17, Issue:15

    Topics: Anesthesia, Inhalation; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Antineoplastic Agen

1975
[Malignant hyperthermia treated with procaine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Sep-30, Volume: 95, Issue:27

    Topics: Adolescent; Anesthesia, Inhalation; Humans; Male; Malignant Hyperthermia; Procaine

1975
Letter: Treatment of idiopathic malignant hyperthermia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:5

    Topics: Calcium; Cardiac Glycosides; Humans; Lidocaine; Malignant Hyperthermia; Procainamide; Procaine

1976
[The anesthetic management of a patient with the malignant hyperthermia trait diagnosed preoperatively].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:6

    Topics: Adolescent; Anesthesia, Epidural; Humans; Male; Malignant Hyperthermia; Orthopedics; Procaine

1991
[Temporary registration of cases of peranesthetic malignant hyperthermia in France].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Anesthesia, General; Child; Creatine Kinase; Dantrolene; Epidemiologic Methods; F

1985
[A case of malignant hyperthermia in operative obstetrics].
    Zentralblatt fur Gynakologie, 1985, Volume: 107, Issue:15

    Topics: Adult; Cesarean Section; Combined Modality Therapy; Dantrolene; Female; Humans; Infant, Newborn; Mal

1985
Letter: Procaine and malignant hyperthermia.
    Lancet (London, England), 1974, Feb-09, Volume: 1, Issue:7850

    Topics: Animals; Caffeine; Drug Interactions; Guinea Pigs; Halothane; Malignant Hyperthermia; Muscle Rigidit

1974
Letter: Procaine and malignant hyperthermia.
    Lancet (London, England), 1974, Mar-02, Volume: 1, Issue:7853

    Topics: Dose-Response Relationship, Drug; Female; Humans; Hypotension; Injections, Intravenous; Malignant Hy

1974
Editorial: Malignant hyperthermia: a pharmacogenetic disease of skeletal and cardiac muscle.
    The New England journal of medicine, 1974, May-16, Volume: 290, Issue:20

    Topics: Adenosine Triphosphatases; Biopsy; Calcium; Creatine Kinase; Extracorporeal Circulation; Humans; Mal

1974
[Malignant hyperthermia: a dangerous anesthesia complication. (Diagnosis and therapy)].
    Zentralblatt fur Chirurgie, 1974, Sep-06, Volume: 99, Issue:36

    Topics: Anesthesia, Inhalation; Anesthetics; Baths; Carbonates; Cryotherapy; Fever; Humans; Malignant Hypert

1974
Proceedings: Studies of the therapeutic value of procaine and lignocaine in malignant hyperpyrexia.
    British journal of anaesthesia, 1974, Volume: 46, Issue:4

    Topics: Animals; Calcium; Diaphragm; Drug Evaluation; Halothane; Humans; In Vitro Techniques; Lidocaine; Mal

1974
Procaine in malignant hyperpyrexia.
    British medical journal, 1972, Dec-02, Volume: 4, Issue:5839

    Topics: Aged; Caffeine; Female; Halothane; Humans; In Vitro Techniques; Lidocaine; Malignant Hyperthermia; M

1972
Histopathological and neuropharmacological aspects of malignant hyperpyrexia.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:1 Pt 1

    Topics: Adult; Anesthesia, General; Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; H

1973
Malignant hyperpyrexia.
    Anaesthesia, 1973, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male

1973
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Mo

1973
Biochemical basis of malignant hyperpyrexia.
    British medical journal, 1974, May-04, Volume: 2, Issue:5913

    Topics: Biopsy; Caffeine; Calcium; Cell Membrane; Creatine Kinase; Extracellular Space; Halothane; Humans; I

1974
Letter: Procaine for malignant hyperthermia.
    The New England journal of medicine, 1974, Jul-25, Volume: 291, Issue:4

    Topics: Humans; Malignant Hyperthermia; Procaine

1974
A pack for the emergency treatment of malignant hyperpyrexia.
    Anaesthesia, 1974, Volume: 29, Issue:4

    Topics: Bicarbonates; Chlorpromazine; Dexamethasone; Diazepam; Emergencies; Epinephrine; Equipment and Suppl

1974