Page last updated: 2024-11-03

procaine and Alzheimer Disease

procaine has been researched along with Alzheimer Disease in 3 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Many of the neurochemical changes associated with aging brain, particularly lower choline acetyltransferase and higher monoamine oxidase, occur with greater severity in senile dementia, Alzheimer's type (SDAT)."4.76Chemotherapy of cognitive disorders in geriatric subjects. ( Gershon, S; Goodnick, P, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goodnick, P1
Gershon, S2
Reisberg, B1
Ferris, SH1
Hollister, LE1

Reviews

2 reviews available for procaine and Alzheimer Disease

ArticleYear
Chemotherapy of cognitive disorders in geriatric subjects.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:5

    Topics: Adrenocorticotropic Hormone; Aged; Aging; Alzheimer Disease; Arecoline; Brain Chemistry; Choline; Co

1984
Pharmacotherapy of senile dementia.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Adult; Age Factors; Aged; Alzheimer Disease; Amphetamine; Antidepressive Agents, Tricyclic; Dementia

1980

Other Studies

1 other study available for procaine and Alzheimer Disease

ArticleYear
Alzheimer's disease. Is it worth treating?
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Aged; Alzheimer Disease; Dementia; Dihydroergotoxine; Humans; Nafronyl; Papaverine; Pentoxifylline;

1985