procaine has been researched along with Allodynia in 6 studies
Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The area of punctate hyperalgesia was maintained in older adults over 4 h, while it declined in the young." | 2.74 | The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study. ( Gibson, SJ; Helme, RD; McMeeken, JM; Zheng, Z, 2009) |
| "Histamine 10 microl was injected into each bleb, and the resulting magnitude of itch estimated." | 2.69 | Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia. ( Atanassoff, PG; Brull, SJ; Greenquist, K; Lamotte, RH; Silverman, DG; Zhang, J, 1999) |
| "We hypothesized that thermal hyperalgesia also would accelerate the development of tachyphylaxis." | 1.29 | Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade. ( Berde, CB; Lee, KC; Smith, RL; Wilder, RT, 1994) |
| "In this model, thermal hyperalgesia accelerated tachyphylaxis, and the noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist, MK-801, prevented both hyperalgesia and tachyphylaxis." | 1.29 | NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner. ( Berde, CB; Sholas, MG; Wilder, RT, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, Z | 1 |
| Gibson, SJ | 1 |
| Helme, RD | 1 |
| McMeeken, JM | 1 |
| Gerdemann, U | 1 |
| Brückl, V | 1 |
| Nassr, NA | 1 |
| Märkert, D | 1 |
| Sittl, R | 1 |
| Koppert, W | 1 |
| Lee, KC | 1 |
| Wilder, RT | 2 |
| Smith, RL | 1 |
| Berde, CB | 2 |
| Sholas, MG | 1 |
| Atanassoff, PG | 1 |
| Brull, SJ | 1 |
| Zhang, J | 1 |
| Greenquist, K | 1 |
| Silverman, DG | 1 |
| Lamotte, RH | 1 |
| Coderre, TJ | 1 |
| Melzack, R | 1 |
3 trials available for procaine and Allodynia
| Article | Year |
|---|---|
The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study.
Topics: Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Capsaicin; Female; Humans; Hyperalgesi | 2009 |
[Differentiation of peripheral and central hyperalgesic effects of systemic procaine].
Topics: Anesthetics, Local; Capsaicin; Double-Blind Method; Humans; Hyperalgesia; Infusions, Parenteral; Inj | 2004 |
Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Forearm; Histamine; Humans; Hy | 1999 |
3 other studies available for procaine and Allodynia
| Article | Year |
|---|---|
Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade.
Topics: Animals; Circadian Rhythm; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Male; Nerve Block; Pr | 1994 |
NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner.
Topics: Anesthetics, Local; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Double-Blind Met | 1996 |
Cutaneous hyperalgesia: contributions of the peripheral and central nervous systems to the increase in pain sensitivity after injury.
Topics: Animals; Burns; Capsaicin; Central Nervous System; Guanethidine; Hyperalgesia; Hyperesthesia; Male; | 1987 |