Page last updated: 2024-11-03

procaine and Allodynia

procaine has been researched along with Allodynia in 6 studies

Procaine: A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
procaine : A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

Research Excerpts

ExcerptRelevanceReference
"The area of punctate hyperalgesia was maintained in older adults over 4 h, while it declined in the young."2.74The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study. ( Gibson, SJ; Helme, RD; McMeeken, JM; Zheng, Z, 2009)
"Histamine 10 microl was injected into each bleb, and the resulting magnitude of itch estimated."2.69Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia. ( Atanassoff, PG; Brull, SJ; Greenquist, K; Lamotte, RH; Silverman, DG; Zhang, J, 1999)
"We hypothesized that thermal hyperalgesia also would accelerate the development of tachyphylaxis."1.29Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade. ( Berde, CB; Lee, KC; Smith, RL; Wilder, RT, 1994)
"In this model, thermal hyperalgesia accelerated tachyphylaxis, and the noncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist, MK-801, prevented both hyperalgesia and tachyphylaxis."1.29NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner. ( Berde, CB; Sholas, MG; Wilder, RT, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zheng, Z1
Gibson, SJ1
Helme, RD1
McMeeken, JM1
Gerdemann, U1
Brückl, V1
Nassr, NA1
Märkert, D1
Sittl, R1
Koppert, W1
Lee, KC1
Wilder, RT2
Smith, RL1
Berde, CB2
Sholas, MG1
Atanassoff, PG1
Brull, SJ1
Zhang, J1
Greenquist, K1
Silverman, DG1
Lamotte, RH1
Coderre, TJ1
Melzack, R1

Trials

3 trials available for procaine and Allodynia

ArticleYear
The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study.
    Pain, 2009, Volume: 144, Issue:1-2

    Topics: Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Capsaicin; Female; Humans; Hyperalgesi

2009
[Differentiation of peripheral and central hyperalgesic effects of systemic procaine].
    Schmerz (Berlin, Germany), 2004, Volume: 18, Issue:3

    Topics: Anesthetics, Local; Capsaicin; Double-Blind Method; Humans; Hyperalgesia; Infusions, Parenteral; Inj

2004
Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia.
    Somatosensory & motor research, 1999, Volume: 16, Issue:4

    Topics: Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Forearm; Histamine; Humans; Hy

1999

Other Studies

3 other studies available for procaine and Allodynia

ArticleYear
Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade.
    Anesthesiology, 1994, Volume: 81, Issue:5

    Topics: Animals; Circadian Rhythm; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Male; Nerve Block; Pr

1994
NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:6

    Topics: Anesthetics, Local; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Double-Blind Met

1996
Cutaneous hyperalgesia: contributions of the peripheral and central nervous systems to the increase in pain sensitivity after injury.
    Brain research, 1987, Feb-24, Volume: 404, Issue:1-2

    Topics: Animals; Burns; Capsaicin; Central Nervous System; Guanethidine; Hyperalgesia; Hyperesthesia; Male;

1987