procainamide has been researched along with Torsade de Pointes in 10 studies
Procainamide: A class Ia antiarrhythmic drug that is structurally-related to PROCAINE.
procainamide : A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The incidence of clinical torsade de pointes (TdP) associated with amiodarone has been reported to be low and the present study compared the proarrhythmic potential of amiodarone with that of a selective IKr channel blocker, sematilide, using a canine chronic atrioventrucular block model." | 3.71 | Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. ( Hashimoto, K; Ishida, Y; Kugiyama, K; Satoh, Y; Sugiyama, A; Yoneyama, M; Yoshida, H, 2002) |
| "Its precise effect on the prevention of ventricular tachycardia-ventricular fibrillation (VTVF) compared to class I agents has not been evaluated in a blinded study." | 2.68 | Multicenter trial of sotalol compared with procainamide in the suppression of inducible ventricular tachycardia: a double-blind, randomized parallel evaluation. Sotalol Multicenter Study Group. ( Kehoe, R; Quart, B; Scheinman, M; Singh, BN; Woosley, RL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kramer, J | 1 |
| Obejero-Paz, CA | 1 |
| Myatt, G | 1 |
| Kuryshev, YA | 1 |
| Bruening-Wright, A | 1 |
| Verducci, JS | 1 |
| Brown, AM | 1 |
| Yoshida, H | 1 |
| Sugiyama, A | 2 |
| Satoh, Y | 1 |
| Ishida, Y | 1 |
| Yoneyama, M | 1 |
| Kugiyama, K | 1 |
| Hashimoto, K | 2 |
| Singh, BN | 1 |
| Kehoe, R | 1 |
| Woosley, RL | 1 |
| Scheinman, M | 1 |
| Quart, B | 1 |
| Buckingham, TA | 1 |
| Bhutto, ZR | 1 |
| Telfer, EA | 1 |
| Zbilut, J | 1 |
| Makkar, RR | 1 |
| Fromm, BS | 1 |
| Steinman, RT | 1 |
| Meissner, MD | 1 |
| Lehmann, MH | 1 |
| Laub, GW | 1 |
| Muralidharan, S | 1 |
| Janeira, L | 1 |
| Moore, RA | 1 |
| Clancy, R | 1 |
| Adkins, MS | 1 |
| Fernandez, J | 1 |
| Anderson, WA | 1 |
| McGrath, LB | 1 |
| Trohman, RG | 1 |
| Sahu, J | 1 |
| Stroh, JA | 1 |
| Wong, W | 1 |
| Pavlou, HN | 1 |
| Birgersdotter, UM | 1 |
| Hilleman, DE | 1 |
| Mohiuddin, SM | 1 |
| Roden, DM | 1 |
1 review available for procainamide and Torsade de Pointes
| Article | Year |
|---|---|
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramid | 1993 |
2 trials available for procainamide and Torsade de Pointes
| Article | Year |
|---|---|
Multicenter trial of sotalol compared with procainamide in the suppression of inducible ventricular tachycardia: a double-blind, randomized parallel evaluation. Sotalol Multicenter Study Group.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cardiac Pacing, Artificial; Double-Blind Method; Elec | 1995 |
Pharmacology of the class III antiarrhythmic agent sematilide in patients with arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrocardiography; | 1992 |
7 other studies available for procainamide and Torsade de Pointes
| Article | Year |
|---|---|
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp T | 2013 |
Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Dogs; Dose-Respo | 2002 |
Differences in corrected QT intervals at minimal and maximal heart rate may identify patients at risk for torsades de pointes during treatment with antiarrhythmic drugs.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Electrocardiography; Female; Forecasting; Heart Rat | 1994 |
Refractory postoperative torsades de pointes syndrome successfully treated with isoproterenol.
Topics: Atrial Fibrillation; Coronary Artery Bypass; Female; Humans; Internal Mammary-Coronary Artery Anasto | 1993 |
Drug-induced torsade de pointes.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Heart Arrest; Humans; Male; Procainam | 1999 |
Effects of a typical I(Kr) channel blocker sematilide on the relationship between ventricular repolarization, refractoriness and onset of torsades de pointes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cation Transport Proteins; Dogs; Ether-A-Go-Go P | 2002 |
Labored breathing in an elderly woman with hypertension.
Topics: Aged; Aged, 80 and over; Bradycardia; Cardiac Complexes, Premature; Dyspnea; Electrocardiography; Fe | 1992 |